CAJ | 학술논문

目的探讨伴胼胝体压部可逆性病变的轻度脑炎/脑病(MERS)的临床及头颅影像学特征.方法报道1例MERS患儿临床及影像学特点.对以下数据库2000年1月至2013年6月收录的论文进行检索:中国期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、美国国家生物技术中心(NCBI)、生物医学文献数据库(PubMed)、万方数据知识服务平台,共收集已报道的44例MERS儿童患者临床及影像学特点,对其进行分析.结果本例MERS发生前的基础疾病为呼吸道支原体感染,病程第2天出现脑病症状,头颅MRI为胼胝体压部、半卵圆中心及侧脑室后角病变,3周内临床及影像学完全恢复.44例MERS患儿多发生于感染性疾病过程中,临床有意识障碍、惊厥、构音障碍等表现;头颅MRI为胼胝体压部病变,除胼胝体压部受累外,还包括胼胝体膝部、半卵圆中心、额叶白质等部位,临床症状及影像多于2周内恢复正常.结论 MERS表现为在急性炎症疾病过程中出现急性轻微脑病症状,头颅MRI表现为胼胝体压部可逆性病变,短期内可完全恢复.
목적 탐토반변지체압부가역성병변적경도뇌염/뇌병(MERS)적림상급두로영상학특정.방법 보도1례MERS환인림상급영상학특점.대이하수거고2000년1월지2013년6월수록적논문진행검색:중국기간전문수거고(CNKI)、중국생물의학문헌수거고(CBM)、미국국가생물기술중심(NCBI)、생물의학문헌수거고(PubMed)、만방수거지식복무평태,공수집이보도적44례MERS인동환자림상급영상학특점,대기진행분석.결과 본례MERS발생전적기출질병위호흡도지원체감염,병정제2천출현뇌병증상,두로MRI위변지체압부、반란원중심급측뇌실후각병변,3주내림상급영상학완전회복.44례MERS환인다발생우감염성질병과정중,림상유의식장애、량궐、구음장애등표현;두로MRI위변지체압부병변,제변지체압부수루외,환포괄변지체슬부、반란원중심、액협백질등부위,림상증상급영상다우2주내회복정상.결론 MERS표현위재급성염증질병과정중출현급성경미뇌병증상,두로MRI표현위변지체압부가역성병변,단기내가완전회복.
Objective To investigate the characteristics of a new clinical-image syndrome-mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) of corpus callosum.Method The clinical and imaging features of one pediatric patient with the diagnosis of MERS were analyzed and the clinical and radiologic data of 44 MERS cases which were reported all around the world were also analyzed.Result The underlying disease of the patient before the onset was respiratory mycoplasma infection.On the second day of the disease course,the patient presented symptoms of encephalopathy.Brain MRI indicated lesions in the splenium of corpus callosum,centrum semiovate and posterior periventricular white matter.And these lesions recovered completely within 3 weeks.Most of the 44 patients diagnosed with MERS were associated with infectious diseases and completely recovered within two weeks.Symptoms included consciousness disturbance,convulsions and dysarthria.In addition to the splenium,brain MRI also showed lesions in genu of corpus callosum,centrum semiovate and white matter of frontal lobe.Conclusion The clinical presentations of MERS were sudden onset of symptoms of encephalopathy during acute inflammation.Brain MRI indicated a reversible lesion in the splenium of corpus callosum.Patients recover completely within a few days.