CAJ | 학술논문

目的分析4例SLE合并乳糜性胸腹腔积液患者的临床资料,探讨两者的关系.方法回顾性分析首都医科大学附属北京世纪坛医院2000年1月至2013年6月诊治的4例SLE合并乳糜性胸腹腔积液患者的临床资料、辅助检查及治疗转归等资料,并复习国内外文献.结果 4例患者均为女性;年龄31～47岁;SLE合并乳糜性胸腹腔积液的病程3～12个月.4例合并乳糜性胸腹腔积液患者中3例为乳糜性胸腹腔积液,1例为乳糜性胸腔积液.4例患者中3例给予糖皮质激素治疗,2例联合免疫抑制剂(环磷酰胺或环孢素A)治疗,1例患者临床症状明显缓解.结论 SLE累及淋巴系统出现乳糜性胸腹腔积液相对少见,应当引起风湿免疫科医生的重视,早期干预,积极治疗,改善患者的生活质量及预后.
목적 분석4례SLE합병유미성흉복강적액환자적림상자료,탐토량자적관계.방법 회고성분석수도의과대학부속북경세기단의원2000년1월지2013년6월진치적4례SLE합병유미성흉복강적액환자적림상자료、보조검사급치료전귀등자료,병복습국내외문헌.결과 4례환자균위녀성;년령31～47세;SLE합병유미성흉복강적액적병정3～12개월.4례합병유미성흉복강적액환자중3례위유미성흉복강적액,1례위유미성흉강적액.4례환자중3례급여당피질격소치료,2례연합면역억제제(배린선알혹배포소A)치료,1례환자림상증상명현완해.결론 SLE루급림파계통출현유미성흉복강적액상대소견,응당인기풍습면역과의생적중시,조기간예,적겁치료,개선환자적생활질량급예후.
Objective To investigate the clinical features of 4 cases with systemic lupus erythematosus (SLE) complicated by chylothorax and chylous ascites.Methods Clinical manifestations,laboratory examinations,treatment and prognosis of 4 patients with SLE complicated by chylothorax and chylous ascites,who were admitted to our center in recent 13 years,were retrospectively analyzed.Results Four patients were female.The average age of SLE at presentation was 38 years (ranging from 31 to 47 years of age).The average disease duration of chylothorax and chylous ascites was 6.5 months (ranging from 3 to 12 months).Of the 4 patients,3 were complicated with chylothorax and chylous ascites,and 1 with chylothorax.Three patients were treated with corticosteroid,and 2 patients were treated combined with immuno-suppressive agents (cyclophosphamide or ciclosporin A).Chylothorax and chylous ascites improved in 1 patient.Conclusion The clinical manifesta-tions of chylothorax and chylous ascites are relatively rare in patients with systemic lupus erythematosus,and more attention should be given to improve the quality of life of these patients.