中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2011年
10期
929-932
,共4页
尹刚%赵世华%陆敏杰%蒋世良%程怀兵%马宁%张岩%凌坚%杨新令%安靖%SvenZuehlsdorff%RenataJerecic
尹剛%趙世華%陸敏傑%蔣世良%程懷兵%馬寧%張巖%凌堅%楊新令%安靖%SvenZuehlsdorff%RenataJerecic
윤강%조세화%륙민걸%장세량%정부병%마저%장암%릉견%양신령%안정%SvenZuehlsdorff%RenataJerecic
心脏病%磁共振成像%研究技术
心髒病%磁共振成像%研究技術
심장병%자공진성상%연구기술
Heart diseases%Magnetic resonance imaging%Investigative techniques
目的 评价自由呼吸膈肌导航三维相位敏感反转恢复( PSIR)磁矩预准备快速小角度激发( Turbo-FLASH)序列在心脏MRI评估冠心病左心室瘢痕中的应用价值.方法 23例临床有明确心肌梗死的患者,静脉注射钆对比剂,10～15 min后,先行二维PSIR Turbo-FLASH序列成像.随后,立即行三维PSIR Turbo-FLASH序列自由呼吸下成像.由2名医师独立对MRI总体质量进行等级评分.再按照美国心脏学会17节段法,对左心室钆对比剂延迟强化(LGE)的面积和类型进行半定量分析,对LGE的体积进行定量评估.两种方法变量间的比较采用配对t检验或秩和检验,Pearson相关和线性回归模型评价两者之间的相关性和依存关系.结果 23例心肌梗死患者的二维和三维图像,总体质量分别为(2.57±0.59)和(2.39±0.66)分(Z=-0.93,P=0.35)；瘢痕的面积积分分别为(24.48±10.83)和(29.00±11.56)分(Z=- 1.41,P=0.16)；类型分别为(16.78 ±6.51)和( 18.87 ±6.76)分(Z=-1.17,P=0.24)；差异均无统计学意义.三维比二维LGE体积定量更大:二维和三维分别为(23.46±10.61)和(31.65±13.86) cm3(t=-2.25,P=0.03).进一步分析显示延迟强化体积定量二维和三维之间呈现出良好的相关性(r =0.940,P＜0.01)和依存性(y=2.851+1.228x,R2=0.883).结论 自由呼吸下三维PSIR Turbo-FLASH序列对比剂延迟增强成像比常规二维序列能够更准确地显示心肌梗死后瘢痕,是更加有效检测心肌活性的新技术.
目的 評價自由呼吸膈肌導航三維相位敏感反轉恢複( PSIR)磁矩預準備快速小角度激髮( Turbo-FLASH)序列在心髒MRI評估冠心病左心室瘢痕中的應用價值.方法 23例臨床有明確心肌梗死的患者,靜脈註射釓對比劑,10～15 min後,先行二維PSIR Turbo-FLASH序列成像.隨後,立即行三維PSIR Turbo-FLASH序列自由呼吸下成像.由2名醫師獨立對MRI總體質量進行等級評分.再按照美國心髒學會17節段法,對左心室釓對比劑延遲彊化(LGE)的麵積和類型進行半定量分析,對LGE的體積進行定量評估.兩種方法變量間的比較採用配對t檢驗或秩和檢驗,Pearson相關和線性迴歸模型評價兩者之間的相關性和依存關繫.結果 23例心肌梗死患者的二維和三維圖像,總體質量分彆為(2.57±0.59)和(2.39±0.66)分(Z=-0.93,P=0.35)；瘢痕的麵積積分分彆為(24.48±10.83)和(29.00±11.56)分(Z=- 1.41,P=0.16)；類型分彆為(16.78 ±6.51)和( 18.87 ±6.76)分(Z=-1.17,P=0.24)；差異均無統計學意義.三維比二維LGE體積定量更大:二維和三維分彆為(23.46±10.61)和(31.65±13.86) cm3(t=-2.25,P=0.03).進一步分析顯示延遲彊化體積定量二維和三維之間呈現齣良好的相關性(r =0.940,P＜0.01)和依存性(y=2.851+1.228x,R2=0.883).結論 自由呼吸下三維PSIR Turbo-FLASH序列對比劑延遲增彊成像比常規二維序列能夠更準確地顯示心肌梗死後瘢痕,是更加有效檢測心肌活性的新技術.
목적 평개자유호흡격기도항삼유상위민감반전회복( PSIR)자구예준비쾌속소각도격발( Turbo-FLASH)서렬재심장MRI평고관심병좌심실반흔중적응용개치.방법 23례림상유명학심기경사적환자,정맥주사구대비제,10～15 min후,선행이유PSIR Turbo-FLASH서렬성상.수후,립즉행삼유PSIR Turbo-FLASH서렬자유호흡하성상.유2명의사독립대MRI총체질량진행등급평분.재안조미국심장학회17절단법,대좌심실구대비제연지강화(LGE)적면적화류형진행반정량분석,대LGE적체적진행정량평고.량충방법변량간적비교채용배대t검험혹질화검험,Pearson상관화선성회귀모형평개량자지간적상관성화의존관계.결과 23례심기경사환자적이유화삼유도상,총체질량분별위(2.57±0.59)화(2.39±0.66)분(Z=-0.93,P=0.35)；반흔적면적적분분별위(24.48±10.83)화(29.00±11.56)분(Z=- 1.41,P=0.16)；류형분별위(16.78 ±6.51)화( 18.87 ±6.76)분(Z=-1.17,P=0.24)；차이균무통계학의의.삼유비이유LGE체적정량경대:이유화삼유분별위(23.46±10.61)화(31.65±13.86) cm3(t=-2.25,P=0.03).진일보분석현시연지강화체적정량이유화삼유지간정현출량호적상관성(r =0.940,P＜0.01)화의존성(y=2.851+1.228x,R2=0.883).결론 자유호흡하삼유PSIR Turbo-FLASH서렬대비제연지증강성상비상규이유서렬능구경준학지현시심기경사후반흔,시경가유효검측심기활성적신기술.
Objective To assess the value of free-breathing 3D phase sensitive inversion recovery (PSIR) turbo FLASH for demonstrating the left ventricular myocardial scar in patients with myocardial infarction.Methods Twenty-three patients with myocardial infarction underwent 2D and 3D phase sensitive inversion recovery (PSIR) Turbo FLASH sequences 10-15 minutes after injection of dimeglumine gadopentetate.The image quality,the area,location and volume of hyperenhanced scar were independently assessed by two experienced radiologists.Student′s t test or rank sum test and Pearson linear correlation were used for the statistics.Results There were no significant differences in the overall image quality (2.57 ±0.59 vs 2.39 ±0.66,Z=-0.93,P =0.35),the area (24.48 ±10.83 vs 29.00 ± 11.56,Z=-1.41,P =0.16) and location ( 16.78 ± 6.51 vs 18.87 ± 6.76,Z =- 1.17,P =0.24) of hyperenhanced scar between 2D and 3D PSIR sequences.The mean volume of hyperenhanced scar was significantly greater in 3D PSIR sequence than that in 2D PSI R sequence [(23.46 ± 10.61 ) vs (31.65 ± 13.86) cm3,t =-2.25,P =0.03].There was a good correlation in the volume of hyperenhanced scar between 2D PSIR and 3D PSIR sequences (r=0.940,P＜0.01 ;y =2.851 + 1.228x,R2 =0.883).Conclusion Free-breathing 3D PSIR Turbo FLASH is a promising new imaging technique for accurate assessment of myocardial scar.
