CAJ | 학술논문

目的探讨延迟增强MRI (DE-MRI)检测心肌梗死积分与近期心脏事件的相关性.方法 40例经完整资料确诊的冠心病患者行DE-MRI心肌梗死积分评价、超声心动图射血分数(EF)测量、每周硝酸甘油次数、每周心绞痛发作次数及最近1年心功能不全发作次数、6 min步行距离评价及西雅图心绞痛健康状况(SAQ)评分.结果行Spearman秩相关分析、完全随机设计多个样本比较及两两比较.结果 DE-MRI心肌梗死积分[12分(四分位数间距:6.0～ 19.8分)]与6min步行距离(378.93±100.53)、SAQ(74.55±11.40)呈轻至中度负相关(r值分别为0.66、0.54,P＜0.05)；每周硝酸甘油次数[1次(四分位数间距:0～2.8次)]、每周心绞痛发作次数[3次(四分位数间距:1.0 ～6.5次)]及最近1年心功能不全发作次数[0次(四分位数间距:0～2次)]呈高度正相关(r值分别为0.87、0.85、0.89,P值均＜0.05),高于EF值[(49.2±13.72)％]与相应心脏事件的相关系数.结论 DE-MRI检测的心肌梗死积分可用于近期心脏事件发生的预测,相对于传统的EF评价,其对于冠心病近期心脏事件发生的预测有更高的价值.
목적 탐토연지증강MRI (DE-MRI)검측심기경사적분여근기심장사건적상관성.방법 40례경완정자료학진적관심병환자행DE-MRI심기경사적분평개、초성심동도사혈분수(EF)측량、매주초산감유차수、매주심교통발작차수급최근1년심공능불전발작차수、6 min보행거리평개급서아도심교통건강상황(SAQ)평분.결과행Spearman질상관분석、완전수궤설계다개양본비교급량량비교.결과 DE-MRI심기경사적분[12분(사분위수간거:6.0～ 19.8분)]여6min보행거리(378.93±100.53)、SAQ(74.55±11.40)정경지중도부상관(r치분별위0.66、0.54,P＜0.05)；매주초산감유차수[1차(사분위수간거:0～2.8차)]、매주심교통발작차수[3차(사분위수간거:1.0 ～6.5차)]급최근1년심공능불전발작차수[0차(사분위수간거:0～2차)]정고도정상관(r치분별위0.87、0.85、0.89,P치균＜0.05),고우EF치[(49.2±13.72)％]여상응심장사건적상관계수.결론 DE-MRI검측적심기경사적분가용우근기심장사건발생적예측,상대우전통적EF평개,기대우관심병근기심장사건발생적예측유경고적개치.
Objective To investigate the correlation between recent cardiac events and the score of myocardial infarction by delayed-enhancement MRI (DE-MRI).Methods DE-MRI was performed in 40 subjects with coronary artery disease.The score of myocardial infarction by DE-MRI,the ejection fraction (EF) by echocardiography,recent cardiac events (the number of weekly nitroglycerin,the number of weekly angina episodes and the onset number of heart failure in the last year),6-minute walking distance,as well as the Seattle angina questionnaire (SAQ) score were assessed.The Spearman correlation test and Kruskal-Wallis test,Mann-Whitney test were used for the statistics.Results There were negative correlation between the myocardial infarction score by DE-MRI (median 12,inter-quartile range:6.0-19.8) and the 6-minute walking distance(378.93 ± 100.53 ),SAQ score (74.55 ± 11.40 ) (r was 0.66 and 0.54,P ＜0.05).The myocardial infarction score by DE-MRI was strongly correlated with the number of weekly nitroglycerin ( median 1 ; inter-quartile range:0-2.8),the number of weekly angina episodes ( median 3,inter-quartile range:1-6.5 ) and the onset number of heart failure in the last year ( median 0,inter-quartile range:0-2) (r was 0.87,0.85 and 0.89,P ＜0.05).EF [(49.2 ± 13.72)％] was negative correlation with the number of weekly nitroglycerin,the number of weekly angina episodes and the onset number of heart failure in the last year (r were 0.67,0.73 and 0.73,P ＜0.05).Conclusion DE-MRI can be used for evaluation and prediction of future cardiac events.