CAJ | 학술논문

目的探讨乳腺实性乳头状癌(SPC)的影像表现和临床病理特征.方法回顾性分析经手术病理证实的15例SPC患者资料,15例行MR检查,11例行乳腺X线摄影,观察患者影像表现和病理特征.结果 15例SPC病理均可见实性乳头状形态,分子型均为Luminal A型乳腺癌,14例神经内分泌标记阳性.仪3例在乳腺X线上发现病灶,15例病变均在MRI上显示.11例病变位于乳晕后区,11例T1WI示导管扩张,12例T2WI呈高信号.增强扫描表现为非肿块样强化的10例中,5例为导管样点簇状强化,4例为段样卵石样强化,1例为区域样不均匀强化；表现为肿块样强化的5例均呈环形不均匀强化.结论乳腺X线难以发现SPC,MRI表现具有特征性,和病理特征有关.
목적 탐토유선실성유두상암(SPC)적영상표현화림상병리특정.방법 회고성분석경수술병리증실적15례SPC환자자료,15례행MR검사,11례행유선X선섭영,관찰환자영상표현화병리특정.결과 15례SPC병리균가견실성유두상형태,분자형균위Luminal A형유선암,14례신경내분비표기양성.의3례재유선X선상발현병조,15례병변균재MRI상현시.11례병변위우유훈후구,11례T1WI시도관확장,12례T2WI정고신호.증강소묘표현위비종괴양강화적10례중,5례위도관양점족상강화,4례위단양란석양강화,1례위구역양불균균강화；표현위종괴양강화적5례균정배형불균균강화.결론 유선X선난이발현SPC,MRI표현구유특정성,화병리특정유관.
Objective To investigate the appearance of solid papillary carcinoma (SPC)of breast on MRI and mammography correlated with histopathological features.Methods Fifteen patients with breast SPC diagnosed from January 2011 to January 2013 were enrolled.Their MR and mammography imaging findings were retrospectively reviewed,15 patients had MRI and 11 patients had mammography.The correlation between pathological characteristics and imaging findings was made.Results All the SPC displayed a solid-papillary growth pattern together with Luminal A type,and 14 cases showed neuroendocrine markers.On mammography,only three cases showed the abnormality.The most frequently seen MRI feature was its location in the posterior of areola (11 cases),ductal ectasia on T1WI (11 cases) and high signal intensity on T2WI.The enhancement patterns included non-mass-like enhancement (10 cases),mostly manifested as ductal with clumped enhancement (5 cases) and segmental with pebble shaped enhancement (4 cases),whereas mass-like enhancement (5 cases) exhibited as annular heterogeneous enhancement.Conclusions SPC is difficult to detect on mammography,but the MRI features may suggest its distinct histological type as papillary tumor.The ultimate diagnosis still depends on histopathology and immunohistochemical results.