CAJ | 학술논문

目的探讨丙泊酚联合亚低温治疗大面积脑梗塞的疗效,为临床治疗提供参考.方法将42例大面积脑梗塞患者随机分为治疗组22例和对照组20例.对照组应用亚低温及常规治疗;治疗组在对照组的基础上应用丙泊酚治疗;观察治疗效果,比较两组临床疗效.结果治疗5d后,治疗组神经功能缺损疗效有效率为39.9％,高于对照组的20.0％;试验组死亡率为9.1％,低于对照组的20.0％;差异均具有统计学意义(P＜0.05);试验组总的意识状态改善强于对照组.结论丙泊酚对促进大面积脑梗塞急性期患者神经功能的恢复有疗效,并能降低死亡率.
목적 탐토병박분연합아저온치료대면적뇌경새적료효,위림상치료제공삼고.방법 장42례대면적뇌경새환자수궤분위치료조22례화대조조20례.대조조응용아저온급상규치료;치료조재대조조적기출상응용병박분치료;관찰치료효과,비교량조림상료효.결과 치료5d후,치료조신경공능결손료효유효솔위39.9％,고우대조조적20.0％;시험조사망솔위9.1％,저우대조조적20.0％;차이균구유통계학의의(P＜0.05);시험조총적의식상태개선강우대조조.결론 병박분대촉진대면적뇌경새급성기환자신경공능적회복유료효,병능강저사망솔.
Objective To explore the curative effect of propofol in combination with mild hypothermia for cerebral infarction in large area and provide some references for its clinical treatment.Methods 42 patients with cerebral infarction in large area were randomly divided into a treatment group (22 cases) and a control groups (20 cases).The control group received conventional treatment and mild hypothermia.In addition,the treatment group were treated with propofol.The clinical efficacies of both groups was compared.Results 5 datys after the treatment,the effective rate of neurologic deficits was 39.9％ in treatment group and was 20.0％ in the control group; the mortality rate was 9.1％ in the treatment group and was 20.0％ in the control group; with statistical differences (P＜0.05).The state of consciousness was improved more in the treatment group than in the control group.Conclusions Propofol can recover the neurological function of the patients with acute massive cerebral infarction and reduce the mortality.