中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2014年
11期
893-896
,共4页
邓明%王良%李亮%李拔森%蔡杰%闵祥德%冯朝燕%冯定义%郭紫成
鄧明%王良%李亮%李拔森%蔡傑%閔祥德%馮朝燕%馮定義%郭紫成
산명%왕량%리량%리발삼%채걸%민상덕%풍조연%풍정의%곽자성
前列腺肿瘤%磁共振成像%冷冻疗法
前列腺腫瘤%磁共振成像%冷凍療法
전렬선종류%자공진성상%냉동요법
Prostate Neoplasms%Magnetic resonance imaging%Cryotherapy
目的 探讨多参数MRI(Mp-MRI)在前列腺癌(PCa)氩氦刀冷冻消融术后评估消融切缘的价值.方法 回顾性分析经穿刺病理确诊为PCa后行氩氦刀冷冻治疗,且在治疗后行3.0 TMp-MRI检查的13例患者.患者均行前列腺及精囊常规MRI、DWI和灌注加权成像(PWI)检查.观察冷冻后切缘信号特征,测量冷冻消融中心的ADC值.对T2WI、DWI、PWI序列图像PCa冷冻术后切缘进行评分,并采用非参数秩和检验进行比较.结果 9例T2WI切缘呈高或稍高信号,消融切缘清晰.DWI消融切缘2例清晰,残腔中心ADC值为(0.644±0.121)×10-3 s/mm2.PWI 12例切缘清晰,切缘动脉早期均呈强化高信号.采用T2WI、DWI、PWI对术后消融切缘的评分中位数分别为4(2～5)、3(2～4)、5(3～5)分,差异有统计学意义(H=0.602,P=0.022),两两比较差异均有统计学意义(P均＜0.05).结论Mp-MRI在PCa氩氦刀冷冻治疗术后评估切缘具有一定价值,PWI较DWI、T2WI可以更好地显示PCa切缘.
目的 探討多參數MRI(Mp-MRI)在前列腺癌(PCa)氬氦刀冷凍消融術後評估消融切緣的價值.方法 迴顧性分析經穿刺病理確診為PCa後行氬氦刀冷凍治療,且在治療後行3.0 TMp-MRI檢查的13例患者.患者均行前列腺及精囊常規MRI、DWI和灌註加權成像(PWI)檢查.觀察冷凍後切緣信號特徵,測量冷凍消融中心的ADC值.對T2WI、DWI、PWI序列圖像PCa冷凍術後切緣進行評分,併採用非參數秩和檢驗進行比較.結果 9例T2WI切緣呈高或稍高信號,消融切緣清晰.DWI消融切緣2例清晰,殘腔中心ADC值為(0.644±0.121)×10-3 s/mm2.PWI 12例切緣清晰,切緣動脈早期均呈彊化高信號.採用T2WI、DWI、PWI對術後消融切緣的評分中位數分彆為4(2～5)、3(2～4)、5(3～5)分,差異有統計學意義(H=0.602,P=0.022),兩兩比較差異均有統計學意義(P均＜0.05).結論Mp-MRI在PCa氬氦刀冷凍治療術後評估切緣具有一定價值,PWI較DWI、T2WI可以更好地顯示PCa切緣.
목적 탐토다삼수MRI(Mp-MRI)재전렬선암(PCa)아양도냉동소융술후평고소융절연적개치.방법 회고성분석경천자병리학진위PCa후행아양도냉동치료,차재치료후행3.0 TMp-MRI검사적13례환자.환자균행전렬선급정낭상규MRI、DWI화관주가권성상(PWI)검사.관찰냉동후절연신호특정,측량냉동소융중심적ADC치.대T2WI、DWI、PWI서렬도상PCa냉동술후절연진행평분,병채용비삼수질화검험진행비교.결과 9례T2WI절연정고혹초고신호,소융절연청석.DWI소융절연2례청석,잔강중심ADC치위(0.644±0.121)×10-3 s/mm2.PWI 12례절연청석,절연동맥조기균정강화고신호.채용T2WI、DWI、PWI대술후소융절연적평분중위수분별위4(2～5)、3(2～4)、5(3～5)분,차이유통계학의의(H=0.602,P=0.022),량량비교차이균유통계학의의(P균＜0.05).결론Mp-MRI재PCa아양도냉동치료술후평고절연구유일정개치,PWI교DWI、T2WI가이경호지현시PCa절연.
Objective To investigate the delineation and visualization of the margin of ablation for prostate cancer in multi-parametric MRI (Mp-MRI) of prostate cancer argon-helium cryosurgery.Methods Thirteen patients with suspected prostate cancer underwent Mp-MRI at a 3.0 T MR before and within one week to three months after cryosurgery.The delineation and visualization of the margin of ablation for prostate cancer in T2WI,DWI and perfusion weighted imaging (PWI) had been prospectively interpreted by 2 radiologists.ADC value was recoded in the middle of the ablation for prostate cancer.Comparisons between T2WI,DWI,PWI were evaluated using the Kruskal-Wallis test and Mann-Whitney test.Results Of the 13 cases,the margin of ablation for prostate cancer were clearly delineated in 9 on T2WI,2 on DWI and 12 on PWI.ADC value was (0.644±0.121)× 10-3 s/mm2.In the delineation and visualization of the margin of ablation for prostate cancer,the grade were 4(2 to 5),3(2 to 4) and 5(3 to 5)in T2WI,DWI and PWI,there was significant difference among them(H=0.602,P=0.022),and there were significant difference between them (P＜0.05).Conclusions Mp-MRI provides a powerful tool for noninvasive evaluation of frozen tissue created by focal cryoablation of prostate cancer.PWI is significantly superior to T2WI and DWI in the delineation and visualization of the margin of ablation for prostate cancer.
