CAJ | 학술논문

目的研究在放射性核素肾动态显像中肾脏和膀胱所受到的内照射剂量.方法建立一个双隔室链肾脏-膀胱排泄模型并推导出相关的数学表达式,模拟放射性核素肾动态显像剂被人体摄入后的转移、排泄过程,计算核素在肾脏、膀胱和人体其余组织内的总衰变数,再采用蒙特卡罗模拟的方法 ,计算核素衰变释放的射线在肾脏以及膀胱内产生的能量沉积,最后根据辐射的品质因数计算它们的有效剂量.结果以131I-OIH和99Tcm-DTPA显像剂为例,肾脏受到的内照射剂量分别为0.058 mGy/MBq(131 I-OIH)和0.0054 mCy/MBq(99Tcm-DTPA);膀胱受到的内照射剂量分别为0.40 mGy/MBq(131I-OIH)和0.033 mCy/MBq(99Tcm-DTPA).结论常规剂量水平下的放射性核素肾动态显像对肾脏和膀胱造成的辐射剂量很小.
목적 연구재방사성핵소신동태현상중신장화방광소수도적내조사제량.방법 건립일개쌍격실련신장-방광배설모형병추도출상관적수학표체식,모의방사성핵소신동태현상제피인체섭입후적전이、배설과정,계산핵소재신장、방광화인체기여조직내적총쇠변수,재채용몽특잡라모의적방법 ,계산핵소쇠변석방적사선재신장이급방광내산생적능량침적,최후근거복사적품질인수계산타문적유효제량.결과 이131I-OIH화99Tcm-DTPA현상제위례,신장수도적내조사제량분별위0.058 mGy/MBq(131 I-OIH)화0.0054 mCy/MBq(99Tcm-DTPA);방광수도적내조사제량분별위0.40 mGy/MBq(131I-OIH)화0.033 mCy/MBq(99Tcm-DTPA).결론 상규제량수평하적방사성핵소신동태현상대신장화방광조성적복사제량흔소.
Objective To study the internal radiation dose in kidney and bladder for the renal dynamic radionuclide-imaging.Methods A double compartment chain related to kidney-bladder excretion model was set out.The correlative mathematical expressions were educed to simulate the absorbed radionuclide medicament for renal dynamic imaging's transfer and excretion.The total disintegration amount in kidney,bladder and other organs was counted.Monte Calor methods were used to calculate the radionuclide disintegration radial energy deposited in kidney and bladder,and their effective doses were calculated according to the radiation quality factor.Results To take 131I-OIH and 99Tcm-DTPA imaging agents for example,the internal radiation dose in kidney was 0.058 mGy/MBq(for 131I-OIH) and 0.0054 mGy/MBq(for 99Tcm-DTPA),respectively,while the internal radiation dose in bladder is 0.40 mGy/MBq(for 131I-OIH) and 0.033 mGy/MBq(for 99Tcm-DTPA),respectively.Conclusions The internal radiation doses in kidney and bladder are very low for renal dynamic radionuclideimaging at the conventional dose.