中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2013年
2期
155-157
,共3页
李永武%孙晓南%王奇%刘海%施国治
李永武%孫曉南%王奇%劉海%施國治
리영무%손효남%왕기%류해%시국치
乳腺癌切除术后%复发%胸壁%调强放疗%治疗计划
乳腺癌切除術後%複髮%胸壁%調彊放療%治療計劃
유선암절제술후%복발%흉벽%조강방료%치료계화
Postmastectomy breast cancer%Recurrence%Chest wall%Intensity modulated radiotherapy%Treatment planning
目的 比较乳腺癌术后胸壁大体积复发2野和6野调强放疗的计划差异.方法 对8例乳腺切除术后胸壁大体积复发病例,Pinnacle计划系统上分别对PTV进行2野调强和6野调强放疗计划设计,PTV处方剂量为50 Gy/25次(GTV后续计划补量至66～70 Gy),比较2种计划95％处方剂量PTV适形指数(CI)、均匀性指数(HI)及心脏、同侧肺剂量.结果 6野IMRT计划的CI和HI均优于2野IMRT计划,6野和2野的CI分别为(0.66±0.08)和(0.53±0.10)(t=7.99,P＜0.05),HI分别为(1.36±0.08)和(2.19±0.78)(t=9.04,P＜0.05).2个计划中肺V5、V10、V20、V35和心脏Dmax、V35、Dmean值比较差异无统计学意义.结论 乳腺癌切除术后胸壁大体积复发患者行放疗,6野静态逆向调强放疗计划靶区覆盖优于2野,而心肺受量方面无明显差异.
目的 比較乳腺癌術後胸壁大體積複髮2野和6野調彊放療的計劃差異.方法 對8例乳腺切除術後胸壁大體積複髮病例,Pinnacle計劃繫統上分彆對PTV進行2野調彊和6野調彊放療計劃設計,PTV處方劑量為50 Gy/25次(GTV後續計劃補量至66～70 Gy),比較2種計劃95％處方劑量PTV適形指數(CI)、均勻性指數(HI)及心髒、同側肺劑量.結果 6野IMRT計劃的CI和HI均優于2野IMRT計劃,6野和2野的CI分彆為(0.66±0.08)和(0.53±0.10)(t=7.99,P＜0.05),HI分彆為(1.36±0.08)和(2.19±0.78)(t=9.04,P＜0.05).2箇計劃中肺V5、V10、V20、V35和心髒Dmax、V35、Dmean值比較差異無統計學意義.結論 乳腺癌切除術後胸壁大體積複髮患者行放療,6野靜態逆嚮調彊放療計劃靶區覆蓋優于2野,而心肺受量方麵無明顯差異.
목적 비교유선암술후흉벽대체적복발2야화6야조강방료적계화차이.방법 대8례유선절제술후흉벽대체적복발병례,Pinnacle계화계통상분별대PTV진행2야조강화6야조강방료계화설계,PTV처방제량위50 Gy/25차(GTV후속계화보량지66～70 Gy),비교2충계화95％처방제량PTV괄형지수(CI)、균균성지수(HI)급심장、동측폐제량.결과 6야IMRT계화적CI화HI균우우2야IMRT계화,6야화2야적CI분별위(0.66±0.08)화(0.53±0.10)(t=7.99,P＜0.05),HI분별위(1.36±0.08)화(2.19±0.78)(t=9.04,P＜0.05).2개계화중폐V5、V10、V20、V35화심장Dmax、V35、Dmean치비교차이무통계학의의.결론 유선암절제술후흉벽대체적복발환자행방료,6야정태역향조강방료계화파구복개우우2야,이심폐수량방면무명현차이.
Objective To compare the dose distribution of reserved planned tangential beam IMRT(2-field IMRT) with multifields beams IMRT(6-field IMRT) of the bulk-recurrent chest wall in postmastectomy breast cancer patients.Methods For 8 patients with chest wall in postmastectomy breast cancer bulk-recurrence,2-field IMRT and 6-field IMRT plans were generated on PTV in Pinnacle Planning System.The prescribed dose of PTV was 50 Gy in 25 fractions and GTV was 66-70 Gy which irradiated incrementally by subsequent plan in 8-10 fractions.The conformal index (CI) and homogeneity index (HI) of 95％ of prescribed dose over PTV were compared,while the dose distribution on ipsilateral lung and heart were evaluated.Results The CI of PTV by 6-field IMRT (0.66 ± 0.08) was higher than that of the2-field IMRT (0.53±0.10)(t=7.99,P＜0.05).The HI ofPTV by6-field IMRT (1.36±0.08)waslower than that of 2-field IMRT (2.19 ±0.78) (t =9.04,P ＜0.05).There was no statistical difference in V5,V10,V20 and V35 for ipsilateral lung and in D V35 and D for heart between two plans.Conclusions Compared with 2-field IMRT,6-field IMRT might have a better dose distribution on planning target volume(PTV) for chest wall in postmastectomy breast cancer bulk-recurrence patients,butthere is no significant difference in dose-volume of ipsilateral lung and heart between two plans.
