CAJ | 학술논문

目的研究采用Delta4三维半导体探测器阵列对螺旋断层治疗(HT)计划实施剂量验证的可行性.方法采用ScandiDos公司Delta4三维半导体探测器阵列验证10例恶性肿瘤患者HT计划.通过该系统兆伏特CT成像和配准来确保实现Delta4探测器阵列的精确摆位.实施质量保证的治疗计划照射后,将Delta4探测器阵列测量获得的平面剂量分布与计划系统模体计划计算获得的进行比较.选择阈值水平分别为5％、10％、20％、70％、90％时3％/2 mm、3％/3 mm、3％/4 mm、3％/5 mm标准分别进行γ通过率验证.结果测量所得剂量分布与计算结果在相应平面几何分布均呈良好一致性.γ平均通过率均＞ 94.89％.结论 Delta4三维探测器阵列用于HT计划验证能获满意结果,一般情况下可有效替代传统胶片验证.
목적 연구채용Delta4삼유반도체탐측기진렬대라선단층치료(HT)계화실시제량험증적가행성.방법 채용ScandiDos공사Delta4삼유반도체탐측기진렬험증10례악성종류환자HT계화.통과해계통조복특CT성상화배준래학보실현Delta4탐측기진렬적정학파위.실시질량보증적치료계화조사후,장Delta4탐측기진렬측량획득적평면제량분포여계화계통모체계화계산획득적진행비교.선택역치수평분별위5％、10％、20％、70％、90％시3％/2 mm、3％/3 mm、3％/4 mm、3％/5 mm표준분별진행γ통과솔험증.결과 측량소득제량분포여계산결과재상응평면궤하분포균정량호일치성.γ평균통과솔균＞ 94.89％.결론 Delta4삼유탐측기진렬용우HT계화험증능획만의결과,일반정황하가유효체대전통효편험증.
Objective To investigate the feasibility of dose verification of intensity modulated planning of helical tomotherapy (HT) using three-dimensional semiconductor array (Delta4) and find a more time-consuming and accurate method to validate the delivery dose.Methods Delta4 detector array was used to verify the HT plan dose distribution of 10 patients.The precise setup of detector array was guided and registered by MVCT imaging.After the implementation of delivery,the measured dose distributions on the corresponding planes were compared with those calculated by the treatment planning system (TPS).According to the different acceptance criteria combination of dose difference or distance to agreement at different threshold level including 3％/2 mm,3％/3 mm,3％/4 mm,3％/5 mm at TH5,TH10,TH20,TH30,TH70,TH90,the γ analysis method was utilized to evaluate the dose verification.Results The dose distribution measured by the Delta4 was well consistent with that calculated by the TPS.The mean γpassing rates were all above 94.89％.Conclusions Delta4 detector array can get satisfying results when used in HT plan dose verification and is a viable tool to replace traditional film dosimetry system in clinical quality assurance work.