CAJ | 학술논문

目的使用仿真人体模型,研究空腔及非均匀组织结构对不同照射技术的剂量学影响.方法利用成都剂量体模,制作具有4cm×4cm×3 cm空腔结构的头颈部模体和胸部切片肺组织模体,按照实际治疗流程进行定位CT扫描和模拟定位机复位,在空腔和非均匀组织结构边界处及其内部粘贴3.2 mm ×3.2 mm ×0.8 mm超薄型热释光剂量片,采用不同照射技术设计治疗计划并在直线加速器上进行实际照射,对热释光剂量片数值进行分析.结果头颈部仿真模体,单野、两野对穿和7个野IMRT计划照射测量结果均存在显著的空腔效应,并且随射野增加和放疗技术的复杂性,空腔效应有减小趋势;对胸部肺组织仿真模体,也存在类似空腔效应.结论对人体组织内部空腔结构或非均匀组织结构,设计计划时应考虑空腔效应影响,给予更多射野或使用更加复杂的照射技术来减小空腔效应影响.
목적 사용방진인체모형,연구공강급비균균조직결구대불동조사기술적제량학영향.방법 이용성도제량체모,제작구유4cm×4cm×3 cm공강결구적두경부모체화흉부절편폐조직모체,안조실제치료류정진행정위CT소묘화모의정위궤복위,재공강화비균균조직결구변계처급기내부점첩3.2 mm ×3.2 mm ×0.8 mm초박형열석광제량편,채용불동조사기술설계치료계화병재직선가속기상진행실제조사,대열석광제량편수치진행분석.결과 두경부방진모체,단야、량야대천화7개야IMRT계화조사측량결과균존재현저적공강효응,병차수사야증가화방료기술적복잡성,공강효응유감소추세;대흉부폐조직방진모체,야존재유사공강효응.결론 대인체조직내부공강결구혹비균균조직결구,설계계화시응고필공강효응영향,급여경다사야혹사용경가복잡적조사기술래감소공강효응영향.
Objective To investigate influence on dose distribution due to cavity and inhomogeneous structures using thermoluminescence dosimeters (TLD) and Chengdu phantoms.Methods A cavity 4 cm × 4 cm × 3 cm was made by a head and neck phantom and a lung phantom was cut into slices which were got a CT scanning and setup in a digital simulator.The TLD were pasted on edge and in the center of cavity structure and inhomogeneous structures.Treatment plans of different radiotherapy technologies were made generated and delivered on a linear accelerator.Then the TLD were read and analyzed.Results There were remarkable cavity effects of conventional single field,opposite fields and IMRT plans with 7 fields for head and neck phantom.There is similar effect in lung phantom.The more complexity the radiotherapy technology was the less cavity effect.Conclusions It is necessary to consider using more advanced radiotherapy technology or applying more fields to make treatment plans in order to decrease the cavity effect or similar effect when there are inhomogeneous structures.