中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2014年
4期
314-317
,共4页
胰腺癌%嗜神经侵袭%神经周间隙%神经生长因子%肿瘤微环境
胰腺癌%嗜神經侵襲%神經週間隙%神經生長因子%腫瘤微環境
이선암%기신경침습%신경주간극%신경생장인자%종류미배경
Pancreatic cancer%Perineural invasion%Perineural space%Nerve growth factor%Tumor microenvironment
胰腺癌较易发生嗜神经侵袭现象,引起患者疼痛和肿瘤的复发,导致预后不良.胰腺和神经组织解剖基础以及肿瘤微环境改变都与胰腺癌嗜神经侵袭密切相关.微环境中有多种因子参与了胰腺癌嗜神经侵袭,同时肿瘤本身也可以改变该微环境.本文从胰腺癌嗜神经现象的解剖和分子生物学角度,综述该现象的研究进展.
胰腺癌較易髮生嗜神經侵襲現象,引起患者疼痛和腫瘤的複髮,導緻預後不良.胰腺和神經組織解剖基礎以及腫瘤微環境改變都與胰腺癌嗜神經侵襲密切相關.微環境中有多種因子參與瞭胰腺癌嗜神經侵襲,同時腫瘤本身也可以改變該微環境.本文從胰腺癌嗜神經現象的解剖和分子生物學角度,綜述該現象的研究進展.
이선암교역발생기신경침습현상,인기환자동통화종류적복발,도치예후불량.이선화신경조직해부기출이급종류미배경개변도여이선암기신경침습밀절상관.미배경중유다충인자삼여료이선암기신경침습,동시종류본신야가이개변해미배경.본문종이선암기신경현상적해부화분자생물학각도,종술해현상적연구진전.
The phenomenon of perineural invasion in pancreatic cancer occurs more easily.It can cause pain and tumor recurrence,and result in poor prognosis.The perineural invasion of pancreas cancer is closely related to the anatomical basis of pancreas and nerve tissue as well as the changes in the tumor microenvironment.Multiple factors in the microenvironment take part in the development of perineural invasion,meanwhile,the tumor tissue itself can also change the microenvironment.This article is to overview the research on the anatomy and molecular biology of perineural invasion of pancreas cancer.
