CAJ | 학술논문

目的分析2010至2013年资助“运动系统”疾病相关各分支学科的情况,对该领域的发展趋势提出思考与展望.方法统计国家自然科学基金2010至2013年度对“运动医学”等领域的资助数量和经费,分析各分支学科基础研究概况,并对研究前沿和热点问题进行初步分析.结果 (1)国家自然科学基金给医学科学部H06申请代码下总资助项目819项,总资助经费达38100万元,其中研究项目系列总项目为476项(28501万元)；人才项目系列总项目为343项(9599万元)；(2)面上项目总资助项目数为563项(2.5223亿元)；青年科学基金总资助项目数为277项(6,142万元)；地区基金项目总资助项目数为60项(2,895万元)；(3)获得最多资助依次为H0605(骨、关节、软组织损伤与修复,256项)、H0609(骨、关节、软组织退行性病变,181项)、H0604(骨、关节、软组织医用材料,72项)、H0601(运动系统结构、功能和发育异常,63项)、H0606(骨、关节、软组织移植与重建,60项)；(4)骨组织工程相关领域平均资助率为22.5％,运动相关医学领域为20％,软骨组织工程相关领域为19.5％.在前沿和热点研究中,干细胞相关项目为25.4％、表观遗传学方面为29.1％、自噬相关项目为26.1％(2011年至2013年)；(5)在运动医学获资助项目数量前3位的单位分别为上海交通大学、浙江大学、第二军医大学,资助项目数和金额均呈一致性.结论组织工程研究、运动相关医学领域研究和软骨组织工程仍将会是运动医学领域国家自然科学基金资助的主流方向；干细胞、自噬或表观遗传等热点领域的研究是将来发展的重要方向.
목적 분석2010지2013년자조“운동계통”질병상관각분지학과적정황,대해영역적발전추세제출사고여전망.방법 통계국가자연과학기금2010지2013년도대“운동의학”등영역적자조수량화경비,분석각분지학과기출연구개황,병대연구전연화열점문제진행초보분석.결과 (1)국가자연과학기금급의학과학부H06신청대마하총자조항목819항,총자조경비체38100만원,기중연구항목계렬총항목위476항(28501만원)；인재항목계렬총항목위343항(9599만원)；(2)면상항목총자조항목수위563항(2.5223억원)；청년과학기금총자조항목수위277항(6,142만원)；지구기금항목총자조항목수위60항(2,895만원)；(3)획득최다자조의차위H0605(골、관절、연조직손상여수복,256항)、H0609(골、관절、연조직퇴행성병변,181항)、H0604(골、관절、연조직의용재료,72항)、H0601(운동계통결구、공능화발육이상,63항)、H0606(골、관절、연조직이식여중건,60항)；(4)골조직공정상관영역평균자조솔위22.5％,운동상관의학영역위20％,연골조직공정상관영역위19.5％.재전연화열점연구중,간세포상관항목위25.4％、표관유전학방면위29.1％、자서상관항목위26.1％(2011년지2013년)；(5)재운동의학획자조항목수량전3위적단위분별위상해교통대학、절강대학、제이군의대학,자조항목수화금액균정일치성.결론 조직공정연구、운동상관의학영역연구화연골조직공정잉장회시운동의학영역국가자연과학기금자조적주류방향；간세포、자서혹표관유전등열점영역적연구시장래발전적중요방향.
Objective To summarize the projects funded in the field of locomotor system from National Natural Science Foundation of China (NSFC) during 2010 to 2013.Methods The number and total funds in the field of locomotor medicine from NSFC was statistically analyzed,and the situation of various branches and hot issues were reviewed during 2010 to 2013.Results 1) There were 819 funded projects with the total funds of 381.00 million RMB in H06 of NSFC,including 476 projects (285.01 million RMB) in research programs and 343 projects (95.99 billion RMB) in talent programs; 2) The number of funded project was 563 (252.33 million RMB) in major research plans,277 (61.42 million RMB) in young scientists funds,and 60 (28.95 million RMB) in less developed regions; 3) The funded fields were H0605 (the injury and repair of bone,joints and soft tissue,256 projects),H0609 (the degenerative disease of bone,joints and soft tissue,181 projects),H0604 (the medical materials,72 projects),H0601 (the abnormal structure,function and development of locomotor system,63 projects) and H0606 (the transplantation and reconstruction,60 projects); 4) The average funded rate was 22.5％ in the field of bony tissue engineering,20％ in locomotor related medicine,and 19.5％ in cartilaginous tissue engineering.In research frontier and hot issues,the average funded rate represented as 25.4％ in stem cells,29.1％ in epigenetic related research fields and 26.1％ in autophagy; 5) The top 3 funded units were Shanghai Jiaotong University,Zhejiang University and Second Military Medical University,both in the number and total funds.Conclusion The funded number and funds grew rapidly in the field of Locomotor Medicine from NSFC.The locomotor related medicine and tissue engineering of bone and cartilage will become the mainstream direction,while the stem cells,autophagy or epigenetic related research fields will be rapidly developed in future.