中华航海医学与高气压医学杂志
中華航海醫學與高氣壓醫學雜誌
중화항해의학여고기압의학잡지
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
2013年
5期
321-323
,共3页
高压氧%急性脑梗死%神经功能%认知功能
高壓氧%急性腦梗死%神經功能%認知功能
고압양%급성뇌경사%신경공능%인지공능
Hyperbaric oxygen%Acute cerebral infarction%Neural function%Cognitive function
目的 探讨急性脑梗死患者高压氧(hyperbaric oxygen,HBO)治疗前后神经功能及认知功能的变化,评价HBO治疗急性脑梗死的临床疗效.方法 经患者知情同意并签署知情同意书后,将92例脑梗死患者分为对照组和HBO组,每组46例,2组分别在治疗前、治疗后第(10±2)天、第(90±3)天进行神经功能缺损评分(NIHSS)和Barthel指数(BI)测定,评价神经功能及日常生活能力;2组分别在治疗前和治疗后第(10±2)天进行蒙特利尔认知评估量表(MoCA)评分[2],评价患者的认知功能.结果 2组的NIHSS(8.8±3.1)及BI (54.77±3.08)在第10天差异无统计学意义(P＞0.05),但在第90天,HBO组的NIHSS评分(5.4±2.2)下降,BI(73.69±20.56)升高,与对照组[NIHSS为(6.9±3.5),BI为(60.05±18.22)]比较差异有统计学意义(P＜0.05);HBO组在HBO治疗第10天后,其视空间、注意力、语言、定向力得分及MoCA总分较对照组提高,2组比较差异有统计学意义(P＜0.05).结论 HBO治疗急性脑梗死临床有效,近期即能改善患者认知能力,远期还可改善患者神经功能及日常生活能力.
目的 探討急性腦梗死患者高壓氧(hyperbaric oxygen,HBO)治療前後神經功能及認知功能的變化,評價HBO治療急性腦梗死的臨床療效.方法 經患者知情同意併籤署知情同意書後,將92例腦梗死患者分為對照組和HBO組,每組46例,2組分彆在治療前、治療後第(10±2)天、第(90±3)天進行神經功能缺損評分(NIHSS)和Barthel指數(BI)測定,評價神經功能及日常生活能力;2組分彆在治療前和治療後第(10±2)天進行矇特利爾認知評估量錶(MoCA)評分[2],評價患者的認知功能.結果 2組的NIHSS(8.8±3.1)及BI (54.77±3.08)在第10天差異無統計學意義(P＞0.05),但在第90天,HBO組的NIHSS評分(5.4±2.2)下降,BI(73.69±20.56)升高,與對照組[NIHSS為(6.9±3.5),BI為(60.05±18.22)]比較差異有統計學意義(P＜0.05);HBO組在HBO治療第10天後,其視空間、註意力、語言、定嚮力得分及MoCA總分較對照組提高,2組比較差異有統計學意義(P＜0.05).結論 HBO治療急性腦梗死臨床有效,近期即能改善患者認知能力,遠期還可改善患者神經功能及日常生活能力.
목적 탐토급성뇌경사환자고압양(hyperbaric oxygen,HBO)치료전후신경공능급인지공능적변화,평개HBO치료급성뇌경사적림상료효.방법 경환자지정동의병첨서지정동의서후,장92례뇌경사환자분위대조조화HBO조,매조46례,2조분별재치료전、치료후제(10±2)천、제(90±3)천진행신경공능결손평분(NIHSS)화Barthel지수(BI)측정,평개신경공능급일상생활능력;2조분별재치료전화치료후제(10±2)천진행몽특리이인지평고량표(MoCA)평분[2],평개환자적인지공능.결과 2조적NIHSS(8.8±3.1)급BI (54.77±3.08)재제10천차이무통계학의의(P＞0.05),단재제90천,HBO조적NIHSS평분(5.4±2.2)하강,BI(73.69±20.56)승고,여대조조[NIHSS위(6.9±3.5),BI위(60.05±18.22)]비교차이유통계학의의(P＜0.05);HBO조재HBO치료제10천후,기시공간、주의력、어언、정향력득분급MoCA총분교대조조제고,2조비교차이유통계학의의(P＜0.05).결론 HBO치료급성뇌경사림상유효,근기즉능개선환자인지능력,원기환가개선환자신경공능급일상생활능력.
Objective To explore the changes of neural function and cognitive function in patients with acute cerebral infarction before and after hyperbaric oxygen (HBO) therapy,and also to evaluate the clinical effect of HBO on patients with acute cerebral infarction.Methods With the knowledge and consent of the patients and following the signing of the letter of agreement,92 cases of acute cerebral infarction were divided into two groups:the HBO group and the control group.Before treatment and (10 ± 2)days and (90 ± 3)days after treatment,scores of neural function for the patients of both groups were assessed by using the National Institute of Health Stroke Survey(NIHSS) and Barthel Index(BI) to evaluate their neural function and daily life activity.Before treatment and on day (10 ± 2)after treatment,MoCA scale assessment was performed to evaluate the cognitive function of the patients in the 2 groups.Results At d 10 after treatment,no statistical significance could be noticed in the scores of NIHSS and BI for the patients of the 2 groups (P ＞ 0.05).However,at d 90,scores of NIHSS for the patients of the HBO group decreased,while BI scores elevated,and statistical differences could be noted when comparisons were made between the 2 groups(P ＜ 0.05).After 10 days of HBO therapy,the scores of visual-space,concentration,speech,orientation and total scores of MoCA in the patients of the HBO group increased obviously,when they were compared with those of the control group and statistical significance could be noted between them (P ＜ 0.05).Conclusions HBO therapy was beneficial to patients with acute cerebral infarction.The short-term effect of HBO therapy was that it could improve cognitive function,and its long-term effect was to improve their neural function and daily life activity.
