CAJ | 학술논문

目的探讨~(99)Tc~m-甲氧基异丁基异腈(MIBI)静息心肌灌注显像在川崎病心肌缺血及疗效评价中的临床价值.方法 31例川崎病患儿根据病程分为急性发热期15例、亚急性期9例和恢复期7例3组.对照组5例患儿系怀疑川崎病而行~(99)Tc~m-MIBI静息心肌灌注显像,后经实验室检查排除川崎病和其他心肌疾病者.所有病例均行~(99)Tc~m-MIBI静息心肌灌注显像,部分静息心肌灌注显像阳性者于治疗后6～12个月随访复查,并与其临床转归进行比较.结果对照组静息心肌灌注显像未见异常.31例川崎病患儿静息心肌灌注显像阳性率为41.9%(13/31).其中急性期、亚急性期和恢复期患儿的阳性数分别为6/15例、4/9例和3/7例.其中8例显像阳性者治疗后6～12个月静息心肌灌注显像复查结果显示:缺血明显改善3例,恢复正常4例,1例仍见明显心肌缺血.结论 ~(99)Tc~m-MIBl静息心肌灌注显像能无创、直接、客观地评价川崎病心肌缺血,对川崎病心肌缺血的诊断和随访有一定的临床价值.
목적 탐토~(99)Tc~m-갑양기이정기이정(MIBI)정식심기관주현상재천기병심기결혈급료효평개중적림상개치.방법 31례천기병환인근거병정분위급성발열기15례、아급성기9례화회복기7례3조.대조조5례환인계부의천기병이행~(99)Tc~m-MIBI정식심기관주현상,후경실험실검사배제천기병화기타심기질병자.소유병례균행~(99)Tc~m-MIBI정식심기관주현상,부분정식심기관주현상양성자우치료후6～12개월수방복사,병여기림상전귀진행비교.결과 대조조정식심기관주현상미견이상.31례천기병환인정식심기관주현상양성솔위41.9%(13/31).기중급성기、아급성기화회복기환인적양성수분별위6/15례、4/9례화3/7례.기중8례현상양성자치료후6～12개월정식심기관주현상복사결과 현시:결혈명현개선3례,회복정상4례,1례잉견명현심기결혈.결론 ~(99)Tc~m-MIBl정식심기관주현상능무창、직접、객관지평개천기병심기결혈,대천기병심기결혈적진단화수방유일정적림상개치.
Objective ~(99)Tc~m-methoxyisobutylisonitrile(MIBI)myocardial perfusion imaging was undertaken to detect myocardial ischemia in children with Kawasaki disease in order to evaluate its diagnostic value.Methods Thirty-one children with Kawasaki disease were included.Five children without cardiovascular disease were enrolled as control group.of these 31 study subjects,there were classified into three groups according to their clinical manifestations.There were acute phase(n=15),sub-acute phase(n=9),and chronic phase(n=7).~(99)Tc~m-MIBI myocardial perfusion SPECT imaging was proformed in all patients.Eight patients with positive result repeated their SPECT imaging during 6-12 months after their first scan.Results Thirteen of 31(41.9%)patients were positive in MIBI perfusion imaging.Six(6/15)were at acute phase,4(4/9)were at sub-acute phase, and 3(3/7)were at chronic phase.Of the 8 patients had second MIBI scans,4 were normal,3 improved significantly, only 1 unchanged. Conclusion ~(99)Tc~m-MIBI myocardial perfusion imasins is a useful noninvasive method for diagnosis evaluation of myocardial ischemia in Kawasaki disease.