中华核医学杂志
中華覈醫學雜誌
중화핵의학잡지
CHINESE JOURNAL OF NUCLEAR MEDICINE
2009年
6期
417-420
,共4页
刘秀芹%李文婵%张建飞%姚稚明
劉秀芹%李文嬋%張建飛%姚稚明
류수근%리문선%장건비%요치명
体层摄影术%发射型计算机%单光子%体层摄影术%X线计算机%图像处理%计算机辅助%镓放射性同位素%质量控制
體層攝影術%髮射型計算機%單光子%體層攝影術%X線計算機%圖像處理%計算機輔助%鎵放射性同位素%質量控製
체층섭영술%발사형계산궤%단광자%체층섭영술%X선계산궤%도상처리%계산궤보조%가방사성동위소%질량공제
Tomography,emission-computed,single-photon%Tomography,X-ray computed%Image processing,computer-assisted%Gallium radioisotopes%Quality control
目的 分析平面显像、非衰减校正(NAC)断层显像和CT衰减校正(AC)断层显像等~(67)Ga显像图像采集和处理模式对图像质量和病灶判断的影响.方法 用美国GE Millennium~(TM) VG 5型SPECT/CT仪对31例活动期肺结节病患者行~(67)Ga平面显像、胸部NAC断层显像;并对断层图像行CT AC.图像分析:双盲法阅片,判断平面图像、AC和NAC断层图像的图像质量及病灶数;测量病变与周围正常组织的放射性计数,并测量其比值.采用SPSS 10.0软件,行配对t检验和χ~2检验.结果 图像质量按照平面显像、NAC、Ac顺序依次提高(χ~2=25.880,P<0.001).以活动期结节病患者SPECT/CT示放射性增高的肺门、纵隔淋巴结为"病灶",平面显像发现"病灶"70个,漏诊"病灶"8个;NAC、AC断层图像均发现"病灶"78个.NAC图像中"病灶"的放射性计数明显低于AC图像中"病灶"的放射性计数(15.240±8.865和67.241±35.049,t=-17.230,P<0.001).和NAC图像比较,AC图像"病灶"与肺的放射性比值增高(t=-7.520,P<O.001),"病灶"与肝(t=3.298,P=0.001)及"病灶"与腰椎(t=7.032,P<O.001)的比值降低.结论 ~(67)Ga平面显像因前后组织放射性分布叠加,可能导致漏诊.~(67)Ga NAC断层显像能够较为准确地确定病变淋巴结的三维位置,但图像计数率低、噪声较大.AC断层图像虽未能增加检出的病灶数,但能有效提高NAC计数率,改善图像质量.
目的 分析平麵顯像、非衰減校正(NAC)斷層顯像和CT衰減校正(AC)斷層顯像等~(67)Ga顯像圖像採集和處理模式對圖像質量和病竈判斷的影響.方法 用美國GE Millennium~(TM) VG 5型SPECT/CT儀對31例活動期肺結節病患者行~(67)Ga平麵顯像、胸部NAC斷層顯像;併對斷層圖像行CT AC.圖像分析:雙盲法閱片,判斷平麵圖像、AC和NAC斷層圖像的圖像質量及病竈數;測量病變與週圍正常組織的放射性計數,併測量其比值.採用SPSS 10.0軟件,行配對t檢驗和χ~2檢驗.結果 圖像質量按照平麵顯像、NAC、Ac順序依次提高(χ~2=25.880,P<0.001).以活動期結節病患者SPECT/CT示放射性增高的肺門、縱隔淋巴結為"病竈",平麵顯像髮現"病竈"70箇,漏診"病竈"8箇;NAC、AC斷層圖像均髮現"病竈"78箇.NAC圖像中"病竈"的放射性計數明顯低于AC圖像中"病竈"的放射性計數(15.240±8.865和67.241±35.049,t=-17.230,P<0.001).和NAC圖像比較,AC圖像"病竈"與肺的放射性比值增高(t=-7.520,P<O.001),"病竈"與肝(t=3.298,P=0.001)及"病竈"與腰椎(t=7.032,P<O.001)的比值降低.結論 ~(67)Ga平麵顯像因前後組織放射性分佈疊加,可能導緻漏診.~(67)Ga NAC斷層顯像能夠較為準確地確定病變淋巴結的三維位置,但圖像計數率低、譟聲較大.AC斷層圖像雖未能增加檢齣的病竈數,但能有效提高NAC計數率,改善圖像質量.
목적 분석평면현상、비쇠감교정(NAC)단층현상화CT쇠감교정(AC)단층현상등~(67)Ga현상도상채집화처리모식대도상질량화병조판단적영향.방법 용미국GE Millennium~(TM) VG 5형SPECT/CT의대31례활동기폐결절병환자행~(67)Ga평면현상、흉부NAC단층현상;병대단층도상행CT AC.도상분석:쌍맹법열편,판단평면도상、AC화NAC단층도상적도상질량급병조수;측량병변여주위정상조직적방사성계수,병측량기비치.채용SPSS 10.0연건,행배대t검험화χ~2검험.결과 도상질량안조평면현상、NAC、Ac순서의차제고(χ~2=25.880,P<0.001).이활동기결절병환자SPECT/CT시방사성증고적폐문、종격림파결위"병조",평면현상발현"병조"70개,루진"병조"8개;NAC、AC단층도상균발현"병조"78개.NAC도상중"병조"적방사성계수명현저우AC도상중"병조"적방사성계수(15.240±8.865화67.241±35.049,t=-17.230,P<0.001).화NAC도상비교,AC도상"병조"여폐적방사성비치증고(t=-7.520,P<O.001),"병조"여간(t=3.298,P=0.001)급"병조"여요추(t=7.032,P<O.001)적비치강저.결론 ~(67)Ga평면현상인전후조직방사성분포첩가,가능도치루진.~(67)Ga NAC단층현상능구교위준학지학정병변림파결적삼유위치,단도상계수솔저、조성교대.AC단층도상수미능증가검출적병조수,단능유효제고NAC계수솔,개선도상질량.
Objective ~(67)Ga scintigraphy is an important method in detection of active sarcoidosis.The aim of this research was to study the influence of planar and tomography.with and without CT attenuation correction(AC and NAC),on ~(67)Ga images on the image quality and the ability in detection of lesions.Methods Thirty one patients(13 male,18 female,age range:33-87 years)with sarcoidosis underwent ~(67)Ga planar and tomographic scans.AC and NAC.The imaging quality and the ability in detection of hyper-radioactive lymph nodes in lung hilar and mediastinal(1esion)among the planar,AC and NAC images were compared.The paired t-test and χ~2-test were used for data analysis with SPSS 10.0 software.Results From planar,NAC to AC,the image quality was better and better in proper order(χ~2=25.88,P<0.001).The planar imaging showed seventy lesions.while both AC and NAC images showed seventy-eight lesions.The radioactivity of lesions on AC image was significantly higher than that in NAC image (67.24l±35.049 and 15.240±8.865,respectively,t=-17.230,P<0.001).The radioactivity ratio of lesion to 3.298,7.032,P<0.01,=0.01 and<0.01.Conclusions ~(67)Ga tomographic scintigraphy can impmve the ability in detection of hyperradioactive lung hilar and mediastinal lymph nodes compared with planar image does.CT AC for ~(67)Ga tomography can improve the tomographic imaging quality.
