CAJ | 학술논문

GFR的标准化对非肿瘤患者,特别是肾供体较为重要.目前研究较多的GFR标准化参数有:体表面积(BSA)、细胞外液容积(ECV)和瘦体质量(LBM).BSA的准确测定较为困难,且儿童和肥胖者的标准化效能较差；ECV特别适用于健康儿童的标准化,但肾功能受损患者的临床应用价值明显减低；LBM兼具定量准确、适用范围广等优点,现有研究表明其比BSA和ECV更适用于GFR的标准化,但其影响因素尚待进一步深入研究.
GFR적표준화대비종류환자,특별시신공체교위중요.목전연구교다적GFR표준화삼수유:체표면적(BSA)、세포외액용적(ECV)화수체질량(LBM).BSA적준학측정교위곤난,차인동화비반자적표준화효능교차；ECV특별괄용우건강인동적표준화,단신공능수손환자적림상응용개치명현감저；LBM겸구정량준학、괄용범위엄등우점,현유연구표명기비BSA화ECV경괄용우GFR적표준화,단기영향인소상대진일보심입연구.
Normalizing GFR with variables is important for non-cancer patients,especially for kidney donors.The most frequently evaluated variables are body surface area (BSA),extracellular fluid volume (ECV) and lean body mass (LBM).It is difficult to accurately quantify BSA and the power of BSA normalization decreases in children and obesity population.The ECV normalization is suitable for healthy children,but its clinical value decreases in patients with damaged renal function.The LBM can be accurately measured and has a larger serviceable range in the normalization.Although the influence factors of LBM should be extensively evaluated,the available data indicate that LBM is more suitable in the normalization of GFR than BSA and ECV.