中华核医学与分子影像杂志
中華覈醫學與分子影像雜誌
중화핵의학여분자영상잡지
Chinese Journal of Nuclear Medicine and Molecular Imaging
2013年
5期
347-350
,共4页
王跃涛%王建锋%杨敏福%牛荣
王躍濤%王建鋒%楊敏福%牛榮
왕약도%왕건봉%양민복%우영
心肌收缩同步性%心室功能,左%体层摄影术,发射型计算机,单光子%参考值%MIBI
心肌收縮同步性%心室功能,左%體層攝影術,髮射型計算機,單光子%參攷值%MIBI
심기수축동보성%심실공능,좌%체층섭영술,발사형계산궤,단광자%삼고치%MIBI
Myocardial contraction synchrony%Ventricular function,left%Tomography,emission-computed,single-photon%Reference values%MIBI
目的 应用美国Cedars-Sinai定量门控心肌断层显像(QGS)软件的相位分析技术定量分析健康人左室心肌收缩同步性.方法 对74名健康人[男41名,女33名,平均年龄(60±13)岁]进行运动-静息99Tcm-MIBI G-MPI.应用QGS软件对重建后的静息图像进行自动分析,获得左室心肌收缩同步性参数:相位直方图带宽(BW)和相位标准差(SD),比较不同性别及年龄组(＜60岁组,36名；≥60岁组,38名)间左室心肌收缩同步性的差别.测量左室17个节段的起始相位角度,确定左室心肌最早收缩部位,简单随机抽样选择40名受检者评价QGS软件相位分析技术在同一操作者和不同操作者间的重复性.数据分析采用两样本t检验和直线相关分析.结果 74名受检者左室BW和SD值分别为(37.22±11.71)°和(11.84±5.39)°.男性和女性BW及SD值差异均无统计学意义[BW:(36.00±9.70)°和(38.73±13.84)°；SD:(11.88±5.56)°和(11.79±5.26)°；t=0.96和-0.07,均P＞0.05).年龄≥60岁组较年龄＜60岁组BW宽[(39.95±12.65)°和(34.33±10.00)°；t=-2.11,P＜0.05]；但2年龄组间SD差异无统计学意义[(11.18±4.31)°和(12.54±6.33)°；t=1.08,P＞0.05].74名受检者中,54名(73％)左室心肌收缩从基底部向心尖部扩散,仅20名(27％)由心尖部向基底部扩散.同一操作者2次操作及2名操作者间相位分析结果均相关(r=0.867～0.906,均P＜0.001).结论 健康人左室心肌收缩同步性良好,不同性别间无明显差异,年龄＜60岁者心肌收缩同步性较≥60岁者更好.QGS心脏相位分析软件是可定量评价左室心肌收缩同步性的工具,且重复性好.
目的 應用美國Cedars-Sinai定量門控心肌斷層顯像(QGS)軟件的相位分析技術定量分析健康人左室心肌收縮同步性.方法 對74名健康人[男41名,女33名,平均年齡(60±13)歲]進行運動-靜息99Tcm-MIBI G-MPI.應用QGS軟件對重建後的靜息圖像進行自動分析,穫得左室心肌收縮同步性參數:相位直方圖帶寬(BW)和相位標準差(SD),比較不同性彆及年齡組(＜60歲組,36名；≥60歲組,38名)間左室心肌收縮同步性的差彆.測量左室17箇節段的起始相位角度,確定左室心肌最早收縮部位,簡單隨機抽樣選擇40名受檢者評價QGS軟件相位分析技術在同一操作者和不同操作者間的重複性.數據分析採用兩樣本t檢驗和直線相關分析.結果 74名受檢者左室BW和SD值分彆為(37.22±11.71)°和(11.84±5.39)°.男性和女性BW及SD值差異均無統計學意義[BW:(36.00±9.70)°和(38.73±13.84)°；SD:(11.88±5.56)°和(11.79±5.26)°；t=0.96和-0.07,均P＞0.05).年齡≥60歲組較年齡＜60歲組BW寬[(39.95±12.65)°和(34.33±10.00)°；t=-2.11,P＜0.05]；但2年齡組間SD差異無統計學意義[(11.18±4.31)°和(12.54±6.33)°；t=1.08,P＞0.05].74名受檢者中,54名(73％)左室心肌收縮從基底部嚮心尖部擴散,僅20名(27％)由心尖部嚮基底部擴散.同一操作者2次操作及2名操作者間相位分析結果均相關(r=0.867～0.906,均P＜0.001).結論 健康人左室心肌收縮同步性良好,不同性彆間無明顯差異,年齡＜60歲者心肌收縮同步性較≥60歲者更好.QGS心髒相位分析軟件是可定量評價左室心肌收縮同步性的工具,且重複性好.
목적 응용미국Cedars-Sinai정량문공심기단층현상(QGS)연건적상위분석기술정량분석건강인좌실심기수축동보성.방법 대74명건강인[남41명,녀33명,평균년령(60±13)세]진행운동-정식99Tcm-MIBI G-MPI.응용QGS연건대중건후적정식도상진행자동분석,획득좌실심기수축동보성삼수:상위직방도대관(BW)화상위표준차(SD),비교불동성별급년령조(＜60세조,36명；≥60세조,38명)간좌실심기수축동보성적차별.측량좌실17개절단적기시상위각도,학정좌실심기최조수축부위,간단수궤추양선택40명수검자평개QGS연건상위분석기술재동일조작자화불동조작자간적중복성.수거분석채용량양본t검험화직선상관분석.결과 74명수검자좌실BW화SD치분별위(37.22±11.71)°화(11.84±5.39)°.남성화녀성BW급SD치차이균무통계학의의[BW:(36.00±9.70)°화(38.73±13.84)°；SD:(11.88±5.56)°화(11.79±5.26)°；t=0.96화-0.07,균P＞0.05).년령≥60세조교년령＜60세조BW관[(39.95±12.65)°화(34.33±10.00)°；t=-2.11,P＜0.05]；단2년령조간SD차이무통계학의의[(11.18±4.31)°화(12.54±6.33)°；t=1.08,P＞0.05].74명수검자중,54명(73％)좌실심기수축종기저부향심첨부확산,부20명(27％)유심첨부향기저부확산.동일조작자2차조작급2명조작자간상위분석결과균상관(r=0.867～0.906,균P＜0.001).결론 건강인좌실심기수축동보성량호,불동성별간무명현차이,년령＜60세자심기수축동보성교≥60세자경호.QGS심장상위분석연건시가정량평개좌실심기수축동보성적공구,차중복성호.
Objective To investigate the value of Cedars-Sinai quantitative gated SPECT (QGS) phase analysis for left ventricular synchrony assessment in healthy subjects.Methods Seventy-four healthy subjects (41 males,33 females,average age:(60±13) years) underwent both rest and exercise 99Tcm-MIBI G-MPI.QGS software was used to analyze the reconstructed rest gated SPECT images automatically,and then the parameters of left ventricular synchrony including phase bandwidth (BW) and phase standard deviation (SD) were obtained.The influences of gender and age (age＜60 years,n =36; age ≥ 60 years,n =38) on left ventricular systolic synchronicity were analyzed.The phase angle for original segmental contraction was measured to determine the onset of the ventricular contraction using 17-segment model.Forty healthy subjects were selected by simple random sampling method to evaluate the intra-observer and interobserver repeatability of QGS phase analysis software.Two-sample t test and linear correlation analysis were used to analyze the data.Results The BW and SD of left ventricular in healthy subjects were (37.22 ±11.71)°,(11.84±5.39)° respectively.Comparisons between male and female for BW and SD yielded no statistical significance (BW:(36.00±9.70)°,(38.73±13.84)°; SD:(11.88±5.56)°,(11.79±5.26)°; t=0.96 and-0.07,both P＞0.05) ; whereas the older subjects (age≥60 years) had larger BW than the others (age＜60 years ; (39.95± 12.65) °,(34.33± 10.00) ° ; t =-2.11,P＜0.05) and no statistical significance was shown for SD between the two age groups ((11.18±4.31) °,(12.54±6.33) ° ; t =1.08,P＞0.05).Of the 74 subjects,the mechanical activation started from the ventricular base to apex in 54 subjects (73％),and from apex to base in only 20 subjects (27％).High repeatability of phase analysis was observed for both intra-observer and inter-observer (r=0.867-0.906,all P＜0.001).Conclusions Good left ventricular segmental synchrony is shown in healthy subjects.No gender difference exists for ventricular synchrony assessment.Age (＜60 years) is important for better synchrony.Cedars-Sinai QGS cardiac phase analysis software is valuable in quantitative assessment of left ventricular synchrony with high repeatability.
