中华核医学与分子影像杂志
中華覈醫學與分子影像雜誌
중화핵의학여분자영상잡지
Chinese Journal of Nuclear Medicine and Molecular Imaging
2013年
6期
430-432
,共3页
陆武%陈鹏%刘永%宋长祥%杜鹏
陸武%陳鵬%劉永%宋長祥%杜鵬
륙무%진붕%류영%송장상%두붕
肺肿瘤%符合线路%体层摄影术,发射型计算机,单光子%体层摄影术,X线计算机%脱氧葡萄糖
肺腫瘤%符閤線路%體層攝影術,髮射型計算機,單光子%體層攝影術,X線計算機%脫氧葡萄糖
폐종류%부합선로%체층섭영술,발사형계산궤,단광자%체층섭영술,X선계산궤%탈양포도당
Lung neoplasms%Coincidence%Tomography,emission-computed,single-photon%Tomography,X-ray computed%Deoxyglucose
目的 探讨18 F-FDG符合线路显像诊断肺部病变良恶性的最佳半定量阈值.方法 对137例肺部病变患者(男89例,女48例,年龄33 ～ 78岁)行18F-FDG符合线路显像,测量肺部病变(T)、正常胸壁软组织(NT1)及对侧相应肺组织(NT2)的最大放射性.以正常胸壁软组织和对侧相对应肺组织为参照点,分别计算肺部病变半定量摄取比值R1(T/NT1)及R2(T/NT2),应用ROC曲线确定肺部病变良恶性的最佳临界值R1(cutoff)、R2(cutoff),并计算其对应的灵敏度、特异性、准确性.结果 R1(cutoff)取3.58,R2(cutoff)取4.40;按此2个最佳临界值,18F-FDG符合线路显像诊断肺部病变的灵敏度、特异性、准确性分别为90.0％ (90/100)、89.2％ (33/37)、89.8％ (123/137)和90.0％ (90/100)、78.4％(29/37)、86.9％ (119/137).结论 以胸壁软组织为参照点,半定量摄取比值取3.58作为18F-FDG符合线路显像诊断肺部病变良恶性的阈值更可靠.
目的 探討18 F-FDG符閤線路顯像診斷肺部病變良噁性的最佳半定量閾值.方法 對137例肺部病變患者(男89例,女48例,年齡33 ～ 78歲)行18F-FDG符閤線路顯像,測量肺部病變(T)、正常胸壁軟組織(NT1)及對側相應肺組織(NT2)的最大放射性.以正常胸壁軟組織和對側相對應肺組織為參照點,分彆計算肺部病變半定量攝取比值R1(T/NT1)及R2(T/NT2),應用ROC麯線確定肺部病變良噁性的最佳臨界值R1(cutoff)、R2(cutoff),併計算其對應的靈敏度、特異性、準確性.結果 R1(cutoff)取3.58,R2(cutoff)取4.40;按此2箇最佳臨界值,18F-FDG符閤線路顯像診斷肺部病變的靈敏度、特異性、準確性分彆為90.0％ (90/100)、89.2％ (33/37)、89.8％ (123/137)和90.0％ (90/100)、78.4％(29/37)、86.9％ (119/137).結論 以胸壁軟組織為參照點,半定量攝取比值取3.58作為18F-FDG符閤線路顯像診斷肺部病變良噁性的閾值更可靠.
목적 탐토18 F-FDG부합선로현상진단폐부병변량악성적최가반정량역치.방법 대137례폐부병변환자(남89례,녀48례,년령33 ～ 78세)행18F-FDG부합선로현상,측량폐부병변(T)、정상흉벽연조직(NT1)급대측상응폐조직(NT2)적최대방사성.이정상흉벽연조직화대측상대응폐조직위삼조점,분별계산폐부병변반정량섭취비치R1(T/NT1)급R2(T/NT2),응용ROC곡선학정폐부병변량악성적최가림계치R1(cutoff)、R2(cutoff),병계산기대응적령민도、특이성、준학성.결과 R1(cutoff)취3.58,R2(cutoff)취4.40;안차2개최가림계치,18F-FDG부합선로현상진단폐부병변적령민도、특이성、준학성분별위90.0％ (90/100)、89.2％ (33/37)、89.8％ (123/137)화90.0％ (90/100)、78.4％(29/37)、86.9％ (119/137).결론 이흉벽연조직위삼조점,반정량섭취비치취3.58작위18F-FDG부합선로현상진단폐부병변량악성적역치경가고.
Objective To explore the optimal semi-quantitative uptake ratio for differentiation between benign and malignant lung lesions with 18F-FDG coincidence imaging.Methods One hundred and thirty-seven patients (89 males,48 females,age range:33-78 years) with lung diseases underwent 18 FFDG coincidence imaging.The maximum radioactivity counts of the lung lesions (T),normal chest wall soft tissues (NT1) and the contralateral lung tissue (NT2) were measured.The ratios of R1 (T/NT1) and R2(T/NT2) were calculated.The optimal threshold values of R1(cutoff)and R2(cutoff) were identified by ROC curve analysis.Using the optimal threshold,the sensitivity,specificity and accuracy were calculated.Results The optimal threshold values R1(cutoff)and R2(cutoff) were identified as 3.58 and 4.40.The sensitivity,specificity and accuracy were 90.0％(90/100),89.2％(33/37),89.8％(123/137) according to R1(cutoff) and 90.0％ (90/100),78.4％(29/37),86.9％(119/137) according to R2(cutoff) Conclusion Based on which the chest wall soft tissue is taken as a reference point,the optimal threshold value of T/NT1 is 3.58 in differentiation between benign and malignant lung lesions with 18F-FDG coincidence imaging.
