中华健康管理学杂志
中華健康管理學雜誌
중화건강관이학잡지
CHINESE JOURNAL OF HEALTH MANAGEMENT
2012年
6期
398-401
,共4页
顾静莉%曹勤%顾伟威%黄融%戴珉%高天%范竹萍
顧靜莉%曹勤%顧偉威%黃融%戴珉%高天%範竹萍
고정리%조근%고위위%황융%대민%고천%범죽평
免疫%球蛋白%IgG抗体%食物不耐受
免疫%毬蛋白%IgG抗體%食物不耐受
면역%구단백%IgG항체%식물불내수
Immunity%Globulins%IgG antibody%Food intolerance
目的 探讨食物不耐受在体检人群中的检测现状及对机体免疫、炎症指标的早期影响.方法 采用酶联免疫吸附法对257例体检人群的血清标本进行食物特异性IgG抗体检测,比较检测结果阳性组和阴性组血白细胞、嗜酸性粒细胞、球蛋白、红细胞沉降率(ESR)、C反应蛋白(CRP)、类风湿因子(RF)、抗核抗体(ANA)及T细胞功能差异.采用SAS软件对相关资料进行t检验或卡方检验.结果 257例受检人群中,食物特异性IgG抗体阳性134例,阳性率为52.14％.排名前三位的阳性食物分别是鸡蛋、螃蟹、牛奶,中、重度不耐受食物主要是鸡蛋和牛奶.比较食物不耐受检测阳性组和阴性组的血嗜酸性粒细胞、球蛋白水平,差异均有统计学意义(t=-0.07,x2=8.91,P＜0.05)；比较两组血白细胞、ESR、CRP、RF、ANA及T细胞功能,均差异无统计学意义(P＞0.05).结论 在临床症状或慢性疾病发生之前,食物不耐受人群的血嗜酸性粒细胞、球蛋白有明显升高,建议加强对这些人群的监测；而对机体血白细胞、ESR、CRP、RF、ANA及T细胞功能等免疫炎症指标无明显影响.
目的 探討食物不耐受在體檢人群中的檢測現狀及對機體免疫、炎癥指標的早期影響.方法 採用酶聯免疫吸附法對257例體檢人群的血清標本進行食物特異性IgG抗體檢測,比較檢測結果暘性組和陰性組血白細胞、嗜痠性粒細胞、毬蛋白、紅細胞沉降率(ESR)、C反應蛋白(CRP)、類風濕因子(RF)、抗覈抗體(ANA)及T細胞功能差異.採用SAS軟件對相關資料進行t檢驗或卡方檢驗.結果 257例受檢人群中,食物特異性IgG抗體暘性134例,暘性率為52.14％.排名前三位的暘性食物分彆是鷄蛋、螃蟹、牛奶,中、重度不耐受食物主要是鷄蛋和牛奶.比較食物不耐受檢測暘性組和陰性組的血嗜痠性粒細胞、毬蛋白水平,差異均有統計學意義(t=-0.07,x2=8.91,P＜0.05)；比較兩組血白細胞、ESR、CRP、RF、ANA及T細胞功能,均差異無統計學意義(P＞0.05).結論 在臨床癥狀或慢性疾病髮生之前,食物不耐受人群的血嗜痠性粒細胞、毬蛋白有明顯升高,建議加彊對這些人群的鑑測；而對機體血白細胞、ESR、CRP、RF、ANA及T細胞功能等免疫炎癥指標無明顯影響.
목적 탐토식물불내수재체검인군중적검측현상급대궤체면역、염증지표적조기영향.방법 채용매련면역흡부법대257례체검인군적혈청표본진행식물특이성IgG항체검측,비교검측결과양성조화음성조혈백세포、기산성립세포、구단백、홍세포침강솔(ESR)、C반응단백(CRP)、류풍습인자(RF)、항핵항체(ANA)급T세포공능차이.채용SAS연건대상관자료진행t검험혹잡방검험.결과 257례수검인군중,식물특이성IgG항체양성134례,양성솔위52.14％.배명전삼위적양성식물분별시계단、방해、우내,중、중도불내수식물주요시계단화우내.비교식물불내수검측양성조화음성조적혈기산성립세포、구단백수평,차이균유통계학의의(t=-0.07,x2=8.91,P＜0.05)；비교량조혈백세포、ESR、CRP、RF、ANA급T세포공능,균차이무통계학의의(P＞0.05).결론 재림상증상혹만성질병발생지전,식물불내수인군적혈기산성립세포、구단백유명현승고,건의가강대저사인군적감측；이대궤체혈백세포、ESR、CRP、RF、ANA급T세포공능등면역염증지표무명현영향.
Objective To discuss current detection of food intolerance in health check-up populations and the influence of food intolerance on immune system and inflammation parameters.Methods Serum levels of 14 kinds of food-specific IgG antibodies were analyzed by using enzyme linked immunosorbent assay (ELISA) among 257 healthy check-up adults.White blood cell count,eosinophils,globulin,erythrocyte sedimentation rate (ESR),C-reactive protein (CRP),rheumatoid factor (RF),antinuclear antibodies (ANA) and T cell function were compared between the positive group and the negative group.Student's t test and Chi-square test were used for data analysis.Results Food-specific IgG antibodies were found in 134 participants (52.14％).The most common intolerant foods were egg,crab and milk.Moderate to severe food intolerance was caused by egg or milk.There was significant difference in eosinophils and serum globulin between the positive and the negative group (t =-0.07,x2 =8.91,both P ＜0.05).However,no difference was observed in white blood cell count,ESR,CRP,RF,ANA and T cell function between two groups (all P ＞ 0.05).Conclusion Eosinophils and serum globulin may significantly increased in people with food intolerance,although white blood cell count,ESR,CRP,RF,ANA and T cell function could be normal.
