中华健康管理学杂志
中華健康管理學雜誌
중화건강관이학잡지
CHINESE JOURNAL OF HEALTH MANAGEMENT
2013年
4期
233-238
,共6页
王娜%仝林虎%王培玉%刘宝花
王娜%仝林虎%王培玉%劉寶花
왕나%동림호%왕배옥%류보화
胆结石%危险因素%病例对照研究
膽結石%危險因素%病例對照研究
담결석%위험인소%병례대조연구
Cholelithiasis%Risk factors%Case-control studies
目的 探讨内蒙古中部地区胆囊结石的危险因素.方法 2010年12月至2011年12月选取内蒙古医学院附属医院的胆囊结石患者并行胆囊切除术180例作为病例组,同期住院的非肝胆疾病的患者200例为对照组.调查内容涉及一般情况、生活行为、疾病史和家族史,测量身高、体重、血压、血脂等指标,采用单因素分析和多因素非条件Logistic回归分析方法,分析胆囊结石的危险因素.结果 病例组和对照组患者的平均年龄分别为(51.7±13.2)岁和(54.6±12.1)岁.病例组中女性130例,男性50例,女性所占比例较高,差异有统计学意义(x2=9.552,P＜0.05).调整年龄、性别混杂因素后,多因素分析结果显示文化程度高(OR=7.05,95％ CI:1.28 ～ 38.85)、食用内脏(OR=12.75,95％ CI:4.67 ～ 34.82)、食用油炸食品(每周食用1次及每周食用2次及以上的OR值分别为9.04、5.39,95％ CI:4.67～17.51、1.60～18.21)、血脂异常(OR=2.81,95％ CI:I.49 ～ 5.30)与胆囊结石的发生呈显著正关联；食用蔬菜(每周2～3次、4～5次及每天1次的OR值分别为0.28、0.09、0.02,95％ CI:0.03 ～2.65、0.01～0.80、0.002～ 0.19)呈负关联.不同性别的胆囊结石危险因素存在差异.结论 喜食内脏、油炸食品,血脂异常可能增加当地人群胆囊结石的发病风险,多食用蔬菜可能降低发病风险.
目的 探討內矇古中部地區膽囊結石的危險因素.方法 2010年12月至2011年12月選取內矇古醫學院附屬醫院的膽囊結石患者併行膽囊切除術180例作為病例組,同期住院的非肝膽疾病的患者200例為對照組.調查內容涉及一般情況、生活行為、疾病史和傢族史,測量身高、體重、血壓、血脂等指標,採用單因素分析和多因素非條件Logistic迴歸分析方法,分析膽囊結石的危險因素.結果 病例組和對照組患者的平均年齡分彆為(51.7±13.2)歲和(54.6±12.1)歲.病例組中女性130例,男性50例,女性所佔比例較高,差異有統計學意義(x2=9.552,P＜0.05).調整年齡、性彆混雜因素後,多因素分析結果顯示文化程度高(OR=7.05,95％ CI:1.28 ～ 38.85)、食用內髒(OR=12.75,95％ CI:4.67 ～ 34.82)、食用油炸食品(每週食用1次及每週食用2次及以上的OR值分彆為9.04、5.39,95％ CI:4.67～17.51、1.60～18.21)、血脂異常(OR=2.81,95％ CI:I.49 ～ 5.30)與膽囊結石的髮生呈顯著正關聯；食用蔬菜(每週2～3次、4～5次及每天1次的OR值分彆為0.28、0.09、0.02,95％ CI:0.03 ～2.65、0.01～0.80、0.002～ 0.19)呈負關聯.不同性彆的膽囊結石危險因素存在差異.結論 喜食內髒、油炸食品,血脂異常可能增加噹地人群膽囊結石的髮病風險,多食用蔬菜可能降低髮病風險.
목적 탐토내몽고중부지구담낭결석적위험인소.방법 2010년12월지2011년12월선취내몽고의학원부속의원적담낭결석환자병행담낭절제술180례작위병례조,동기주원적비간담질병적환자200례위대조조.조사내용섭급일반정황、생활행위、질병사화가족사,측량신고、체중、혈압、혈지등지표,채용단인소분석화다인소비조건Logistic회귀분석방법,분석담낭결석적위험인소.결과 병례조화대조조환자적평균년령분별위(51.7±13.2)세화(54.6±12.1)세.병례조중녀성130례,남성50례,녀성소점비례교고,차이유통계학의의(x2=9.552,P＜0.05).조정년령、성별혼잡인소후,다인소분석결과현시문화정도고(OR=7.05,95％ CI:1.28 ～ 38.85)、식용내장(OR=12.75,95％ CI:4.67 ～ 34.82)、식용유작식품(매주식용1차급매주식용2차급이상적OR치분별위9.04、5.39,95％ CI:4.67～17.51、1.60～18.21)、혈지이상(OR=2.81,95％ CI:I.49 ～ 5.30)여담낭결석적발생정현저정관련；식용소채(매주2～3차、4～5차급매천1차적OR치분별위0.28、0.09、0.02,95％ CI:0.03 ～2.65、0.01～0.80、0.002～ 0.19)정부관련.불동성별적담낭결석위험인소존재차이.결론 희식내장、유작식품,혈지이상가능증가당지인군담낭결석적발병풍험,다식용소채가능강저발병풍험.
Objective To investigate the risk factors of gallstone disease in Inner Mongolia populations.Methods A case-control study was conducted in 180 consecutive patients who had undergone cholecytectomy for gallstones in the hospital of Inner Mongolia during December 2010 to December 2011.Another 200 patients (age 19 to 81 years old) with no gallstone disease were enrolled as controls.All the participants completed a questionnaire and took physical or ultrasonographic examinations.Univariate analysis and Multivariate logistic regression analysis were used for data analysis.Results Mean age of the study group and the control group was (51.7 ± 13.2) and (54.6 ± 12.1) years old,respectively.More female patients were found in the study group (130:50,x2 =9.552,P ＜ 0.05).After adjusting age and gender,multivariate logistic regression showed that gallstone disease was significantly associated with higher educational level (OR =7.05; 95％ confidence internal (CI):1.28-38.85),animal viscera intake (OR =12.75,95 ％ CI:4.67-34.82),fried food intake (once and twice a week:OR =9.04,95％ CI:4.67-17.51; twice a week:OR=5.39,95％ CI:1.60-18.21) and dyslipidaemia (OR=2.81,95％ CI:1.49-5.30).Vegetables intake (2-3 times a week:OR =0.28,95％ CI:0.03-2.65 ; 4-5 times a week:OR =0.09,95 ％ CI:0.01-0.80 ; once a day:OR =0.02,95％ CI:0.002-0.19) was inversely associated with gallstone disease.Risk factors of gallstone disease were different by genders.Conclusions Animal viscera or fried food intake and dyslipidaemia may increase the risk of gallstone disease.However,vegetables intake may prevent the development of gallstone disease.
