CAJ | 학술논문

目的探讨新疆博尔塔拉蒙古自治州地区维吾尔族(维)、哈萨克族(哈)、蒙古族(蒙)和汉族人群的颈围(NC)水平与多种心血管危险因素的关系及民族间差异.方法选自2004年新疆博尔塔拉蒙古自治州维、哈、蒙、汉族代谢综合征的流行病学调查资料4299名,应用Pearson相关分析四民族NC和多个心血管危险因素——体质指数(BMI)、腰围(WC)、腰臀比(WHR)、收缩压(SBP)、舒张压(DBP)、空腹血糖(FBG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、三酰甘油(TG)的相关性,应用多元线性回归分析评价NC变化与多个心血管危险因素水平的关系,应用Logistic回归分析评价NC增加对心血管危险因素(高血压、高FBG、血脂紊乱)患病风险的影响.结果维、哈、蒙、汉四民族的平均NC分别为(36.2±3.8)、(36.3 ±4.1)、(35.9 ±3.6)、(35.7±4.0)cm.NC与BMI(分别维、哈、蒙、汉r=0.552、0.499、0.709、0.459,均P＜0.05)、WC(分别维、哈、蒙、汉r=0.525、0.479、0.695、0.376,均P＜0.05)相关；多元线性回归分析校正BMI、WC及其他因素后,维吾尔族的FBG水平(t=3.746,P＜0.05)及蒙古族的LogTG水平(t=2.876,P＜0.05)随NC水平的增加而增加,且Logistic回归分析NC增加是维吾尔族高FBG(OR=1.139,95％ CI:1.027 ～1.264)以及蒙古族血脂紊乱(OR=1.156,95％ CI:1.009～1.325)患病的危险因素.结论在新疆博尔塔拉蒙古自治州地区维、哈、蒙、汉四民族中NC与多种心血管危险因素相关,并可能存在民族差异.
목적 탐토신강박이탑랍몽고자치주지구유오이족(유)、합살극족(합)、몽고족(몽)화한족인군적경위(NC)수평여다충심혈관위험인소적관계급민족간차이.방법 선자2004년신강박이탑랍몽고자치주유、합、몽、한족대사종합정적류행병학조사자료4299명,응용Pearson상관분석사민족NC화다개심혈관위험인소——체질지수(BMI)、요위(WC)、요둔비(WHR)、수축압(SBP)、서장압(DBP)、공복혈당(FBG)、총담고순(TC)、저밀도지단백담고순(LDL-C)、고밀도지단백담고순(HDL-C)、삼선감유(TG)적상관성,응용다원선성회귀분석평개NC변화여다개심혈관위험인소수평적관계,응용Logistic회귀분석평개NC증가대심혈관위험인소(고혈압、고FBG、혈지문란)환병풍험적영향.결과 유、합、몽、한사민족적평균NC분별위(36.2±3.8)、(36.3 ±4.1)、(35.9 ±3.6)、(35.7±4.0)cm.NC여BMI(분별유、합、몽、한r=0.552、0.499、0.709、0.459,균P＜0.05)、WC(분별유、합、몽、한r=0.525、0.479、0.695、0.376,균P＜0.05)상관；다원선성회귀분석교정BMI、WC급기타인소후,유오이족적FBG수평(t=3.746,P＜0.05)급몽고족적LogTG수평(t=2.876,P＜0.05)수NC수평적증가이증가,차Logistic회귀분석NC증가시유오이족고FBG(OR=1.139,95％ CI:1.027 ～1.264)이급몽고족혈지문란(OR=1.156,95％ CI:1.009～1.325)환병적위험인소.결론 재신강박이탑랍몽고자치주지구유、합、몽、한사민족중NC여다충심혈관위험인소상관,병가능존재민족차이.
Objective To determine the relationship between neck circumference (NC) and cardiovascular risk factors among Uygur,Kazak,Mongolian and Han populations in Boertala Mongol Autonomous Prefecture of Xinjiang.Methods A total of 4299 adults (Uygur 1237,Kazak 1047,Mongolian 812,and Han 1203) aged 20 to 79 years old were selected from a cross-sectional study of metabolic syndrome in Boertala Mongol Autonomous Prefecture of Xinjiang.Pearson's correlation was used to assess the relationship between NC and body mass index (BMI),waist circumference (WC),waist-to-hip ration (WHR),systolic blood pressur (SBP),diastolic blood pressure (DBP),fasting blood glucose (FBG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG).Linear regression and Logistic regression were used to evaluate the effects of NC on SBP,DBP,FBG,TC,LDL-C,HDL-C,TG,hypertension,high FBG and lipid disorders among multiethnic population.Results Mean NC was (36.2 ± 3.8) cm in Uygur,(36.3 ± 4.1) cm in Kazak,(35.9 ± 3.6) cm in Mongolian and (35.7 ± 4.0) cm in Han,respectively.After adjusting age and gender,in Pearson's correlation coefficients,a significant association was found between NC and BMI (for Uygur,Kazak,Mongolian and Han,r values were 0.552,0.499,0.709 and 0.459,respectively; all P ＜ 0.05) or WC (for Uygur,Kazak,Mongolian and Han,r values were 0.525,0.479,0.695 and 0.376,respectively; all P ＜ 0.05).When BMI,WC and other factors were adjusted,linear regression indicated that FBG in Uygur (t =3.746,P ＜ 0.05) and LogTG in Mongolian (t =2.876 P ＜ 0.05) were increased with NC.In Logistic regression,increased NC was a risk factor of higher FBG in Uygur (odds ratio (OR) =1.139,95％confidence interval (CI):1.027-1.264) and lipid disorder in Mongolian (OR =1.156,95％ CI:1.009-1.325).Conclusions Our data suggest that NC may be associated with multiple risk factors of cardiovascular disease in Uygur,Kazak,Mongolian and Han adults,and the relationship could be different among multiethnic populations.It should be necessary to explore the role of upper-body fat in the development of metabolic disorders.