中华精神科杂志
中華精神科雜誌
중화정신과잡지
CHINESE JOURNA OF PSYCHIATRY
2014年
2期
99-102
,共4页
黄若燕%唐牟尼%林康广%郁俊昌%陈映梅%郭伟坚%肖頔%王怀坤%佘生林
黃若燕%唐牟尼%林康廣%鬱俊昌%陳映梅%郭偉堅%肖頔%王懷坤%佘生林
황약연%당모니%림강엄%욱준창%진영매%곽위견%초적%왕부곤%사생림
阿尔茨海默病%痴呆,血管性%死亡率%随访研究
阿爾茨海默病%癡呆,血管性%死亡率%隨訪研究
아이자해묵병%치태,혈관성%사망솔%수방연구
Alzheimer disease%Dementia,vascular%Mortality%Follow-up studies
目的 了解广州市城乡年龄≥55周岁人群中痴呆患者的死亡率.方法 2003年和2008年,采用老年期痴呆初筛调查表、老年期痴呆诊断问卷和死亡患者调查表等调查工具,分别对从广州市城乡5 276名年龄≥55周岁的老年人进行的痴呆患病率(基线)调查中发现的183例痴呆患者进行随访,通过一对一面谈,收集相关资料,包括痴呆死亡人数及总人年数,用两者之比计算出痴呆死亡率.采用DSM-Ⅳ诊断痴呆,采用临床痴呆程度评定量表(CDR)评定痴呆严重程度.结果 (1)基线调查时被评定为痴呆的老年人,7年后随访时的死亡率为18.55/100人年;其中阿尔茨海默病(AD)、血管性痴呆(VD)和其他类型痴呆(OD)患者死亡率分别为17.69/100、19.05/100和32.93/100人年,年龄60～69、70 ～ 79、≥80岁女性的痴呆患者死亡率分别为17.14/100、13.67/100、19.87/100人年.Logistic回归分析显示,年龄[OR=1.05,95％可信区间(CI):1.03 ～ 1.08]和CDR(OR =2.56,95％CI:1.50 ～4.37),对患者死亡存在统计学意义.结论 OD患者死亡率最高,VD患者次之,AD最低.增加痴呆患者死亡危险性的因素有年龄和痴呆程度.低龄痴呆患者的死亡率高于中龄痴呆患者.
目的 瞭解廣州市城鄉年齡≥55週歲人群中癡呆患者的死亡率.方法 2003年和2008年,採用老年期癡呆初篩調查錶、老年期癡呆診斷問捲和死亡患者調查錶等調查工具,分彆對從廣州市城鄉5 276名年齡≥55週歲的老年人進行的癡呆患病率(基線)調查中髮現的183例癡呆患者進行隨訪,通過一對一麵談,收集相關資料,包括癡呆死亡人數及總人年數,用兩者之比計算齣癡呆死亡率.採用DSM-Ⅳ診斷癡呆,採用臨床癡呆程度評定量錶(CDR)評定癡呆嚴重程度.結果 (1)基線調查時被評定為癡呆的老年人,7年後隨訪時的死亡率為18.55/100人年;其中阿爾茨海默病(AD)、血管性癡呆(VD)和其他類型癡呆(OD)患者死亡率分彆為17.69/100、19.05/100和32.93/100人年,年齡60～69、70 ～ 79、≥80歲女性的癡呆患者死亡率分彆為17.14/100、13.67/100、19.87/100人年.Logistic迴歸分析顯示,年齡[OR=1.05,95％可信區間(CI):1.03 ～ 1.08]和CDR(OR =2.56,95％CI:1.50 ～4.37),對患者死亡存在統計學意義.結論 OD患者死亡率最高,VD患者次之,AD最低.增加癡呆患者死亡危險性的因素有年齡和癡呆程度.低齡癡呆患者的死亡率高于中齡癡呆患者.
목적 료해엄주시성향년령≥55주세인군중치태환자적사망솔.방법 2003년화2008년,채용노년기치태초사조사표、노년기치태진단문권화사망환자조사표등조사공구,분별대종엄주시성향5 276명년령≥55주세적노년인진행적치태환병솔(기선)조사중발현적183례치태환자진행수방,통과일대일면담,수집상관자료,포괄치태사망인수급총인년수,용량자지비계산출치태사망솔.채용DSM-Ⅳ진단치태,채용림상치태정도평정량표(CDR)평정치태엄중정도.결과 (1)기선조사시피평정위치태적노년인,7년후수방시적사망솔위18.55/100인년;기중아이자해묵병(AD)、혈관성치태(VD)화기타류형치태(OD)환자사망솔분별위17.69/100、19.05/100화32.93/100인년,년령60～69、70 ～ 79、≥80세녀성적치태환자사망솔분별위17.14/100、13.67/100、19.87/100인년.Logistic회귀분석현시,년령[OR=1.05,95％가신구간(CI):1.03 ～ 1.08]화CDR(OR =2.56,95％CI:1.50 ～4.37),대환자사망존재통계학의의.결론 OD환자사망솔최고,VD환자차지,AD최저.증가치태환자사망위험성적인소유년령화치태정도.저령치태환자적사망솔고우중령치태환자.
Objective To explore the mortality of dementia patients aged 55 years or over in Guangzhou.Methods From Sept 2001 to Feb 2002,5 276 persons aged 55 years or over living in urban and rural areas of Guangzhou were investigated by Senile Dementia Screening Questionnaire,Senile Dementia Diagnosis and Mortality Survey Questionnaire,in which 183 ones were diagnosed with dementia and followed up in 2003 and 2008.According to the information from interview,the dementia mortality was calculated by the ratio of the numbers of dementia deaths and total person-years.The clinical diagnosis of dementia and Alzheimer's disease (AD) were made according to the Diagnostic and Statistic Manual of Mental Disorder,fourth edition(DSM-Ⅳ) criteria.The severity of dementia was assessed with the Clinical Scale for the Staging of Dementia Rate.Results (1) After 7 years the mortality of dementia was 18.55/100 person-years.The mortality rates of patients with Alzheimer's disease (AD),vascular dementia (VD) and other types of dementia (OD) were 17.69/100,19.05/100 and 32.93/100 person-years respectively.The mortality rate of female dementia aged 60-69,70-79,and 80 years or over were 17.14/100,13.67/100 and 19.87/100 person-years respectively.Logistic regression analysis showed that age(OR =1.05,95％ confidence interval (CI):1.03-1.08) and CDR (OR =2.56,95％ CI:1.50-4.37) increased the risk of death.Conclusion The mortality of patients with OD is possibly highest among all the cases and the lowest in patients with AD.Age and the severity of dementia is likely to increase the mortality.The mortality on lower-age patients is higher than that in middle-age patients.
