CAJ | 학술논문

目的探讨职业应激对针织女工月经和性激素的影响.方法以某针织总厂415名女职工为对象,采用职业紧张测量工具调查针织女工的应激情况,同时采集处于月经来潮后3-5 d和来潮前1周女工的血清样本,采用放射免疫法测定黄体酮(P)、雌二醇(E-2)、睾酮(T)、催乳素(PRL)、尿促卵泡素(FSH)和黄体生成素(LH)的含量.分析不同应激程度女工的月经异常情况和激素水平.结果针织女工月经异常率为36.24%,其中月经量异常率为19.80%,月经周期异常率为14.43%;行经期异常率为11.41%,痛经现患率为1.01%.经前期综合征(PMS)现患率为29.19%.分层分析发现,非宫内节育工具(IUD)避孕者抑郁症状得分越高,月经异常率越高;IUD避孕者工作需求和日常紧张感得分越高,行经期异常率越高,无论用IUD避孕与否,日工作时间较长者行经期异常率较高;非IUD避孕组身心症状及抑郁症得分越高者月经量异常率越高;身心症状多与轮班作业可使女工PMS患病率增加;工作时间延长组女工的卵泡期血清中E-2水平下降;工作需求高者卵泡期血清FSH水平下降,而黄体期血清中T水平升高;负性情绪多者黄体期血清中P水平下降.多因素分析表明,身心症状多是女工月经量异常的危险因素;正性情绪少是月经周期异常的危险因素;身心症状多、对工作资源控制程度低和负性生活事件是月经异常的危险因素;身心症状多、轮班是PMS的危险因素;日工作时间延长是行经期异常的危险因素.结论应激程度高可使女工的FSH和E-2水平下降,T水平升高,从而导致月经异常率增高.
목적 탐토직업응격대침직녀공월경화성격소적영향.방법 이모침직총엄415명녀직공위대상,채용직업긴장측량공구조사침직녀공적응격정황,동시채집처우월경래조후3-5 d화래조전1주녀공적혈청양본,채용방사면역법측정황체동(P)、자이순(E-2)、고동(T)、최유소(PRL)、뇨촉란포소(FSH)화황체생성소(LH)적함량.분석불동응격정도녀공적월경이상정황화격소수평.결과 침직녀공월경이상솔위36.24%,기중월경량이상솔위19.80%,월경주기이상솔위14.43%;행경기이상솔위11.41%,통경현환솔위1.01%.경전기종합정(PMS)현환솔위29.19%.분층분석발현,비궁내절육공구(IUD)피잉자억욱증상득분월고,월경이상솔월고;IUD피잉자공작수구화일상긴장감득분월고,행경기이상솔월고,무론용IUD피잉여부,일공작시간교장자행경기이상솔교고;비IUD피잉조신심증상급억욱증득분월고자월경량이상솔월고;신심증상다여륜반작업가사녀공PMS환병솔증가;공작시간연장조녀공적란포기혈청중E-2수평하강;공작수구고자란포기혈청FSH수평하강,이황체기혈청중T수평승고;부성정서다자황체기혈청중P수평하강.다인소분석표명,신심증상다시녀공월경량이상적위험인소;정성정서소시월경주기이상적위험인소;신심증상다、대공작자원공제정도저화부성생활사건시월경이상적위험인소;신심증상다、륜반시PMS적위험인소;일공작시간연장시행경기이상적위험인소.결론 응격정도고가사녀공적FSH화E-2수평하강,T수평승고,종이도치월경이상솔증고.
Objective To investigate the effect of occupational stress on menses and sex hormones. Methods 415 female knitting workers were investigated using the generic job stress questionnaire.Their venous blood were collected and the six sex hormones were detected by using radio-immune method. The different rate of abnormal menses and sex hormones level between different stress degree groups were analyzed. Results The abnormal rate of menses,menstrual blood volume,menstrual cycle,menstrual period was 36.24%, 19.80%, 14.43%, 11.41% respectively. The prevalence rate of dysmenorrheal and premenstrual syndrome was 1.01% and 29.19% respectively. The more depression,the higher menses disorders in non-in-trauterine device (IUD) group. The more job demands,the higher daily stress in IUD group while the longer work time,the more abnormal menstrual period in two groups. More physical symptoms and deeper depression in non-IUD group were related to higher abnormal rate of menstrual blood volume. The level of blood E-2 was lower in the group of prolonged work-time than that of in normal work-time group. The increasing FSH level and decreasing T level was associated with higher job demands. Multiple factor analysis showed that physical symptom,control of resource and negative life affairs were the risk factors of menses disorder; The physical symptom was the risk factor of menstrual blood volume; More physical symptoms, less positive feeling and shift were the risk factors of premenstrual syndrome; Less positive feeling was the risk factor of menstrual cycle; Prolonged daily work-time was the risk factor of menstrual period. Conclusion Higher stress degree can lead to higher FSH and E-2 and lower T level, and induce menses disorder.