中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2013年
1期
45-47
,共3页
陈红霞%邵元鹏%巫丰宏%李艳萍%彭开良
陳紅霞%邵元鵬%巫豐宏%李豔萍%彭開良
진홍하%소원붕%무봉굉%리염평%팽개량
过氯酸铵%职业暴露%甲状腺%多项筛查
過氯痠銨%職業暴露%甲狀腺%多項篩查
과록산안%직업폭로%갑상선%다항사사
Ammonium perchlorate%Thyroid function%Occupational exposure%Multiphasic screening
目的 了解过氯酸铵(AP)粉尘对作业工人健康的影响,为其预防措施提供依据.方法 选择该厂接触AP粉尘的36名作业工人为接触组,不接触AP粉尘的48名该厂工人为对照组.调查工厂的一般情况,监测作业场所的AP粉尘浓度,对两组人群进行职业健康体检,检测血常规、肝肾功能、甲状腺激素指标,进行肺通气功能和X线胸片检查.结果 AP总粉尘浓度以组批车间最高,为(51.63±43.27) mg/m3.接触组收缩压[(146.14±21.03)mmHg]明显高于对照组[(134.67±18.58)mmHg],差异有统计学意义(P＜0.05).接触组全身各系统症状(皮粗、皮痒、气短、咳嗽、咳痰、咽干、疲乏无力等)累计检出率、气短及皮痒的检出率分别为86.11％、30.56％、36.11％,均明显高于对照组(66.67％、12.50％、10.42％),差异均有统计学意义(P＜0.05).接触组的游离三碘甲状腺原氨酸(FT3)水平[(1.29±0.20) ng/ml]明显低于对照组[(1.41±0.23) ng/ml],差异有统计学意义(P＜0.01).接触组工人的1秒用力肺活量与用力肺活量百分比值(FEV1.0/FVC)低于对照组,但差异无统计学意义(P＞0.05).接触组检出1例肺部X线影像异常者,并诊断为尘肺,对照组检出1例左肺门区有1约1.0x1.0小结节影.结论 接触组工人的收缩压明显高于对照组,不排除与接触AP粉尘有关；接触组工人的FT3低于对照组,提示长期接触AP粉尘可能会对作业工人甲状腺功能造成影响.
目的 瞭解過氯痠銨(AP)粉塵對作業工人健康的影響,為其預防措施提供依據.方法 選擇該廠接觸AP粉塵的36名作業工人為接觸組,不接觸AP粉塵的48名該廠工人為對照組.調查工廠的一般情況,鑑測作業場所的AP粉塵濃度,對兩組人群進行職業健康體檢,檢測血常規、肝腎功能、甲狀腺激素指標,進行肺通氣功能和X線胸片檢查.結果 AP總粉塵濃度以組批車間最高,為(51.63±43.27) mg/m3.接觸組收縮壓[(146.14±21.03)mmHg]明顯高于對照組[(134.67±18.58)mmHg],差異有統計學意義(P＜0.05).接觸組全身各繫統癥狀(皮粗、皮癢、氣短、咳嗽、咳痰、嚥榦、疲乏無力等)纍計檢齣率、氣短及皮癢的檢齣率分彆為86.11％、30.56％、36.11％,均明顯高于對照組(66.67％、12.50％、10.42％),差異均有統計學意義(P＜0.05).接觸組的遊離三碘甲狀腺原氨痠(FT3)水平[(1.29±0.20) ng/ml]明顯低于對照組[(1.41±0.23) ng/ml],差異有統計學意義(P＜0.01).接觸組工人的1秒用力肺活量與用力肺活量百分比值(FEV1.0/FVC)低于對照組,但差異無統計學意義(P＞0.05).接觸組檢齣1例肺部X線影像異常者,併診斷為塵肺,對照組檢齣1例左肺門區有1約1.0x1.0小結節影.結論 接觸組工人的收縮壓明顯高于對照組,不排除與接觸AP粉塵有關；接觸組工人的FT3低于對照組,提示長期接觸AP粉塵可能會對作業工人甲狀腺功能造成影響.
목적 료해과록산안(AP)분진대작업공인건강적영향,위기예방조시제공의거.방법 선택해엄접촉AP분진적36명작업공인위접촉조,불접촉AP분진적48명해엄공인위대조조.조사공엄적일반정황,감측작업장소적AP분진농도,대량조인군진행직업건강체검,검측혈상규、간신공능、갑상선격소지표,진행폐통기공능화X선흉편검사.결과 AP총분진농도이조비차간최고,위(51.63±43.27) mg/m3.접촉조수축압[(146.14±21.03)mmHg]명현고우대조조[(134.67±18.58)mmHg],차이유통계학의의(P＜0.05).접촉조전신각계통증상(피조、피양、기단、해수、해담、인간、피핍무력등)루계검출솔、기단급피양적검출솔분별위86.11％、30.56％、36.11％,균명현고우대조조(66.67％、12.50％、10.42％),차이균유통계학의의(P＜0.05).접촉조적유리삼전갑상선원안산(FT3)수평[(1.29±0.20) ng/ml]명현저우대조조[(1.41±0.23) ng/ml],차이유통계학의의(P＜0.01).접촉조공인적1초용력폐활량여용력폐활량백분비치(FEV1.0/FVC)저우대조조,단차이무통계학의의(P＞0.05).접촉조검출1례폐부X선영상이상자,병진단위진폐,대조조검출1례좌폐문구유1약1.0x1.0소결절영.결론 접촉조공인적수축압명현고우대조조,불배제여접촉AP분진유관；접촉조공인적FT3저우대조조,제시장기접촉AP분진가능회대작업공인갑상선공능조성영향.
Objective To understand the occupational hazards of ammonium perchlorate dust on operating workers and to provide the basis preventive measures for protecting the workers' health.Methods 36 workers exposed to ammonium perchlorate dust and 48 unexposed workers from one factory were selected as the exposure and control groups.Investigations on the general condition,sampling of dust in the workplaces and a special medical examination were conducted for two groups,including occupational history,clinical manifestations,blood routine test,hepatic and renal functions,indexes of thyroid hormone,spirometric test and chest X-ray.Results The total dust concentration of AP in the batch plant reached to 51.63±43.27 mg/m3,exceeding the U.S.Occupational Safety and Health Administration (OSHA) permission exposure limits.The systolic blood pressure in the exposure group was higher than that of the control group (146.14±21.03 VS 134.67±18.58),and the difference was statistically significant (P＜0.05).The detection rates of the cumulative total symptoms,short of breath and skin itch symptoms in the exposure group were significantly higher than those in the control group (86.11％ VS 66.67％; 30.56％ VS 12.50％) (P＜0.05),respectively.FT3 level in the exposure group significantly lowered than the control group,and the difference was statistically significant (P＜0.01); The pulmonary function result showed that FEV1/FVC％ in the exposure group was lower than that in the control group (106.50±28.99 VS 111.70±19.72),but the difference was not significant.X-ray examination revealed one case of pulmonary X-ray abnormalities in the exposure group,diagnosis of pneumoconiosis,and one case with about 1.0 x 1.0 small nodules detected on the left of lung door area in the control group.Conclusions The systolic blood pressure of workers in the exposure group was significantly higher,which could not exclude related to the exposure to AP dust; The T3 levels in the exposure workers were lower than those in the control group,which may due to AP exposure,suggesting that long-term chronic exposure to AP dust may affect thyroid function.
