中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2013年
9期
697-700
,共4页
尘肺%病理学%尸体解剖
塵肺%病理學%尸體解剖
진폐%병이학%시체해부
Pneumoconiosis%Pathologg%Autopsy
目的 探讨煤工尘肺的病理组织学特征、并发症、诊断及鉴别诊断.方法 对14例尸检病例的肺组织切片用HE染色光学显微镜下观察,并结合职业史、临床特点进行回顾性分析.结果 14例患者年龄46～71岁(平均57.7岁),2例诊断粉尘性反应,1例为单纯煤工尘肺(煤矽肺Ⅰ期),11例为复杂煤工尘肺(9例为煤矽肺Ⅱ期、1例为Ⅲ期、1例为矽肺Ⅲ期).12例并发慢性支气管炎及肺气肿,8例并发肺心病,4例并发肺结核,3例并发肝硬化、肝癌并肺部转移,2例并发脑出血.结论 接尘时间越长,煤工尘肺病理改变越复杂,煤尘斑是所有煤工尘肺都具有的病理特征,尘性结节和大块状纤维化是病理诊断的必要指标.
目的 探討煤工塵肺的病理組織學特徵、併髮癥、診斷及鑒彆診斷.方法 對14例尸檢病例的肺組織切片用HE染色光學顯微鏡下觀察,併結閤職業史、臨床特點進行迴顧性分析.結果 14例患者年齡46～71歲(平均57.7歲),2例診斷粉塵性反應,1例為單純煤工塵肺(煤矽肺Ⅰ期),11例為複雜煤工塵肺(9例為煤矽肺Ⅱ期、1例為Ⅲ期、1例為矽肺Ⅲ期).12例併髮慢性支氣管炎及肺氣腫,8例併髮肺心病,4例併髮肺結覈,3例併髮肝硬化、肝癌併肺部轉移,2例併髮腦齣血.結論 接塵時間越長,煤工塵肺病理改變越複雜,煤塵斑是所有煤工塵肺都具有的病理特徵,塵性結節和大塊狀纖維化是病理診斷的必要指標.
목적 탐토매공진폐적병리조직학특정、병발증、진단급감별진단.방법 대14례시검병례적폐조직절편용HE염색광학현미경하관찰,병결합직업사、림상특점진행회고성분석.결과 14례환자년령46～71세(평균57.7세),2례진단분진성반응,1례위단순매공진폐(매석폐Ⅰ기),11례위복잡매공진폐(9례위매석폐Ⅱ기、1례위Ⅲ기、1례위석폐Ⅲ기).12례병발만성지기관염급폐기종,8례병발폐심병,4례병발폐결핵,3례병발간경화、간암병폐부전이,2례병발뇌출혈.결론 접진시간월장,매공진폐병리개변월복잡,매진반시소유매공진폐도구유적병리특정,진성결절화대괴상섬유화시병리진단적필요지표.
Objective To investigate the histopathological features,complications,diagnosis,and differential diagnosis of coal workers' pneumoconiosis (CWP).Methods The lung tissue sections from 14 autopsy cases of CWP were subjected to HE staining and observed under a light microscope,and a retrospective analysis was performed considering the occupational history and clinical features.Results The 14 cases were 46-71 years of age (mean,57.7 years).Two cases were diagnosed as dust reaction,1 case as simple CWP (stage Ⅰ anthracosilicosis),and 11 cases as complicated CWP (9 cases of stage Ⅱ anthracosilicosis,1 case of stage Ⅲ anthracosilicosis,and 1 case of stage Ⅲ silicosis).Twelve cases were complicated by chronic bronchitis and emphysema,8 cases by pulmonary heart disease,4 cases by pulmonary tuberculosis,3 cases by liver cirrhosis and liver cancer with pulmonary metastases,and 2 cases by cerebral hemorrhage.Conclusion Among patients with CWP,the pathological changes of lung tissue become more complex with increasing years of dust exposure.Coal macule is the common pathological feature of CWP,and dust nodules and massive fibrosis are the necessary indices of pathological diagnosis.
