中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
11期
935-937
,共3页
代谢综合征X%前列腺增生
代謝綜閤徵X%前列腺增生
대사종합정X%전렬선증생
Metabolic syndrome X%Prostatic hyperplasia
目的 探讨代谢综合征(MS)各相关指标与前列腺体积的相关性. 方法 采用随机数字法从健康查体的10 056例中挑选30~49岁男性843例,测量患者血压、体质量、身高、腰围,并计算体质指数(BMI).生化分析包括检测晨空腹血糖、总胆固醇、三酰甘油(TG)、高密度脂蛋白(HDL-C)、血前列腺特异抗原(PSA),并进行尿常规分析.采用直线回归分析评估MS及相关指标与前列腺体积的相关性. 结果 MS患者前列腺体积(28.3±5.5) ml明显大于对照组(23.2±5.6)ml(P<0.05),空腹血糖、收缩压、BMI、腰围异常组前列腺体积分别为(25.4±5.5) ml、(25.5±5.8)ml、(25.4±5.3)ml、(30.2±4.8)ml,亦大于对照组(23.6±5.5) ml、(23.4±5.4)ml、(22.6±5.5)ml、(23.5±5.3)ml(均P<0.05).前列腺体积与BMI、收缩压、腰围、空腹血糖、TG呈正相关(r=0.397、0.170、0.411、0.216、0.184,均P<0.05),与HDL-C呈负相关(r=-0.107,P<0.05). 结论 MS各相关指标尤其是脂代谢紊乱、血压对前列腺的体积影响显著.
目的 探討代謝綜閤徵(MS)各相關指標與前列腺體積的相關性. 方法 採用隨機數字法從健康查體的10 056例中挑選30~49歲男性843例,測量患者血壓、體質量、身高、腰圍,併計算體質指數(BMI).生化分析包括檢測晨空腹血糖、總膽固醇、三酰甘油(TG)、高密度脂蛋白(HDL-C)、血前列腺特異抗原(PSA),併進行尿常規分析.採用直線迴歸分析評估MS及相關指標與前列腺體積的相關性. 結果 MS患者前列腺體積(28.3±5.5) ml明顯大于對照組(23.2±5.6)ml(P<0.05),空腹血糖、收縮壓、BMI、腰圍異常組前列腺體積分彆為(25.4±5.5) ml、(25.5±5.8)ml、(25.4±5.3)ml、(30.2±4.8)ml,亦大于對照組(23.6±5.5) ml、(23.4±5.4)ml、(22.6±5.5)ml、(23.5±5.3)ml(均P<0.05).前列腺體積與BMI、收縮壓、腰圍、空腹血糖、TG呈正相關(r=0.397、0.170、0.411、0.216、0.184,均P<0.05),與HDL-C呈負相關(r=-0.107,P<0.05). 結論 MS各相關指標尤其是脂代謝紊亂、血壓對前列腺的體積影響顯著.
목적 탐토대사종합정(MS)각상관지표여전렬선체적적상관성. 방법 채용수궤수자법종건강사체적10 056례중도선30~49세남성843례,측량환자혈압、체질량、신고、요위,병계산체질지수(BMI).생화분석포괄검측신공복혈당、총담고순、삼선감유(TG)、고밀도지단백(HDL-C)、혈전렬선특이항원(PSA),병진행뇨상규분석.채용직선회귀분석평고MS급상관지표여전렬선체적적상관성. 결과 MS환자전렬선체적(28.3±5.5) ml명현대우대조조(23.2±5.6)ml(P<0.05),공복혈당、수축압、BMI、요위이상조전렬선체적분별위(25.4±5.5) ml、(25.5±5.8)ml、(25.4±5.3)ml、(30.2±4.8)ml,역대우대조조(23.6±5.5) ml、(23.4±5.4)ml、(22.6±5.5)ml、(23.5±5.3)ml(균P<0.05).전렬선체적여BMI、수축압、요위、공복혈당、TG정정상관(r=0.397、0.170、0.411、0.216、0.184,균P<0.05),여HDL-C정부상관(r=-0.107,P<0.05). 결론 MS각상관지표우기시지대사문란、혈압대전렬선적체적영향현저.
Objective To evaluate the relationship between parameters of MS and prostate volume.Methods A total of 843 men aged 30 to 49 years were enrolled from August 2008 to July 2011.Prostate volume by ultrasonography,serum prostate specific antigen,digital rectal examination,urinary analysis,and MS-related parameters were investigated.We evaluated the correlations of prostate volume with MS and MS components.Results Prostate volume was largerin the MS group (28.3±5.5 ml) than in the non-MS group (23.2±5.6 ml,P<0.05).The prostate volumes in subjects with abnormal levels of fasting plasma glucose (FPG) (25.4±5.5 ml),body mass index (BMI) (25.4±5.3 ml) and waist circumference (30.2±4.8 ml) were increased compared with those of subjects with normal parameters (23.6±5.5 ml,22.6±5.5 and 23.5±5.3 ml,respectively,all P<0.05).The liner regression analysis showed that the FPG,BMI,WC,systolic pressure and triglyceride had a positive correlation with the prostate volume(r=0.216,0.397,0.411,0.170,0.184,respectively; all P<0.05),but negatively related to HDL-C(r=-0.107,P<0.05).Conclusions The patients with abnormal FPG,BMI and waist circumference have larger prostate volume.