中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
11期
938-940
,共3页
沙建军%吴小荣%潘家骅%张连华%宣寒青%李东%薛蔚%薄隽杰%刘东明%黄翼然
沙建軍%吳小榮%潘傢驊%張連華%宣寒青%李東%薛蔚%薄雋傑%劉東明%黃翼然
사건군%오소영%반가화%장련화%선한청%리동%설위%박준걸%류동명%황익연
前列腺肿瘤%肿瘤转移%预后
前列腺腫瘤%腫瘤轉移%預後
전렬선종류%종류전이%예후
Prostatic neoplasms%Neoplasm metastasis%Prognosis
目的 比较前列腺癌根治性切除术后膀胱颈部与精囊侵犯患者的预后. 方法 回顾性分析2002年1月至2008年12月我院接受耻骨后前列腺癌根治性切除术的42例患者,年龄59～78岁,平均70.3岁.42例患者分为pT4a组(膀胱颈部侵犯的患者17例)和pT3b组(单侧或双侧精囊侵犯的患者25例).术后分别采取辅助治疗,定期门诊随访,以术后血清前列腺特异抗原(PSA)连续2次大于0.2 μg/L定义为生化复发,术后随访至发生生化复发的时间或随访至截止日期未发生生化复发的时间定义为无生化复发生存时间. 结果 两组患者术后随访50～122个月,17.6％(3/17)膀胱颈部侵犯者术后发生生化复发,24.0％(6/25)精囊侵犯者发生生化复发,两组比较差异无统计学意义(P＞0.05). 结论 前列腺癌根治术后辅助内分泌治疗能明显延长膀胱颈部侵犯与精囊侵犯的前列腺癌患者无生化复发生存期,但两组无生化复发生存率无差别,可考虑降低膀胱颈部侵犯在TNM系统中的分期.
目的 比較前列腺癌根治性切除術後膀胱頸部與精囊侵犯患者的預後. 方法 迴顧性分析2002年1月至2008年12月我院接受恥骨後前列腺癌根治性切除術的42例患者,年齡59～78歲,平均70.3歲.42例患者分為pT4a組(膀胱頸部侵犯的患者17例)和pT3b組(單側或雙側精囊侵犯的患者25例).術後分彆採取輔助治療,定期門診隨訪,以術後血清前列腺特異抗原(PSA)連續2次大于0.2 μg/L定義為生化複髮,術後隨訪至髮生生化複髮的時間或隨訪至截止日期未髮生生化複髮的時間定義為無生化複髮生存時間. 結果 兩組患者術後隨訪50～122箇月,17.6％(3/17)膀胱頸部侵犯者術後髮生生化複髮,24.0％(6/25)精囊侵犯者髮生生化複髮,兩組比較差異無統計學意義(P＞0.05). 結論 前列腺癌根治術後輔助內分泌治療能明顯延長膀胱頸部侵犯與精囊侵犯的前列腺癌患者無生化複髮生存期,但兩組無生化複髮生存率無差彆,可攷慮降低膀胱頸部侵犯在TNM繫統中的分期.
목적 비교전렬선암근치성절제술후방광경부여정낭침범환자적예후. 방법 회고성분석2002년1월지2008년12월아원접수치골후전렬선암근치성절제술적42례환자,년령59～78세,평균70.3세.42례환자분위pT4a조(방광경부침범적환자17례)화pT3b조(단측혹쌍측정낭침범적환자25례).술후분별채취보조치료,정기문진수방,이술후혈청전렬선특이항원(PSA)련속2차대우0.2 μg/L정의위생화복발,술후수방지발생생화복발적시간혹수방지절지일기미발생생화복발적시간정의위무생화복발생존시간. 결과 량조환자술후수방50～122개월,17.6％(3/17)방광경부침범자술후발생생화복발,24.0％(6/25)정낭침범자발생생화복발,량조비교차이무통계학의의(P＞0.05). 결론 전렬선암근치술후보조내분비치료능명현연장방광경부침범여정낭침범적전렬선암환자무생화복발생존기,단량조무생화복발생존솔무차별,가고필강저방광경부침범재TNM계통중적분기.
Objective To assess the prognosis of patients with bladder neck (BN) involvement in radical prostatectomy specimens and compare it with patients with seminal vesicle invasion (SVI).Methods From January 2002 to December 2008,42 patients with prostate carcinoma who underwent radical prostatectomy were analyzed retrospectively.The mean age was 70.3 years (range 59-78 years).The patients were divided into two groups according to 2002 TNM system:pT4a group (bladder neck invasion) with 17 cases and pT3b group (unilateral or bilateral seminal vesicle invasion)with 25 cases.Postoperative outpatients were followed-up on a regular basis,two consecutive postoperative serums PSA greater than 0.2 μg/L defined as a biochemical recurrence.The postoperative follow-up to the time of biochemical recurrence or follow up to the deadline without biochemical recurrence were defined as biochemical recurrence free survival time.Results All patients were followed up for 50-122 months.The patients with BN involvement 17.6％ (3/17) had biochemical recurrence,whereas seminal vesicle invasion 24.0％ (6/25),there was no statistical significance between the two groups (P＞0.05).Conclusions Postoperative adjuvant therapies can improve the biochemical recurrence free survival.In this study,the prognosis of pT4a and pT3b group is similar.A conceivable down-staging of BN involvement in the TNM staging system should be considered.
