CAJ | 학술논문

目的探讨血浆脑钠肽(BNP)水平对老年左心室射血分数(LVEF)正常的心力衰竭(心衰)患者诊断和治疗的价值.方法选取在我院住院治疗,心脏彩色超声检查LVEF≥45％的患者78例,符合心衰诊断标准的52例为心衰组,左心室舒张功能正常27例为对照组,比较对照组和心衰组心脏超声舒张功能指标和BNP浓度的变化.结果对照组与心衰组比较,BNP浓度(108.7±32.2)ng/L与(190.3±41.5)ng/L、左心室后壁厚度(11.3±1.7)mm与(13.6±1.4)mm、左心室重量指数(119.3±10.2)g/m2与(130.7±8.9)g/m2均升高(P＜0.01).结论 BNP检测可作为诊断心衰的方法之一,BNP与超声心动图联合应用,可提高对老年LVEF正常的心衰患者诊断的准确性.
목적 탐토혈장뇌납태(BNP)수평대노년좌심실사혈분수(LVEF)정상적심력쇠갈(심쇠)환자진단화치료적개치.방법 선취재아원주원치료,심장채색초성검사LVEF≥45％적환자78례,부합심쇠진단표준적52례위심쇠조,좌심실서장공능정상27례위대조조,비교대조조화심쇠조심장초성서장공능지표화BNP농도적변화.결과 대조조여심쇠조비교,BNP농도(108.7±32.2)ng/L여(190.3±41.5)ng/L、좌심실후벽후도(11.3±1.7)mm여(13.6±1.4)mm、좌심실중량지수(119.3±10.2)g/m2여(130.7±8.9)g/m2균승고(P＜0.01).결론 BNP검측가작위진단심쇠적방법지일,BNP여초성심동도연합응용,가제고대노년LVEF정상적심쇠환자진단적준학성.
Objective To investigate the value of brain natriuretic peptide (BNP) detection in the diagnosis and treatment of heart failure patients with normal ejection fraction.Methods Totally 78 elderly patient were selected in our hospital,with left ventricular ejection fraction (LVEF) ≥45 ％,among which 52 cases of patients were consistent of heart failure criteria (heart failure group),27 cases with normal left ventricular diastolic function as control group.The echocardiographic indices of diastolic function and the change of the concentration of BNP were compared.Results As compared with heart failure group,BNP concentration (108.7 ± 32.2) ng/L vs.(190.3 ± 41.5) ng/L,left ventricular posterior wall thickness (11.3 ± 1.7) mm vs.(13.6 ± 1.4) mm,left ventricular mass index (119.3±10.2)g/m2 vs.(130.7±8.9)g/m2 were elevated in heart failure group (all P＜0.01).Conclusions BNP detection can be used for a diagnosis of heart failure as a simple and easy method.The BNP and ultrasound heart beat graph combination can improve heart failure diagnostic accuracywith normal ejection fraction in elderly patients.