中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
3期
305-307
,共3页
胶囊内窥镜检查%5-羟色胺5HT4受体激素剂
膠囊內窺鏡檢查%5-羥色胺5HT4受體激素劑
효낭내규경검사%5-간색알5HT4수체격소제
Capsule endoscopy%Serotonin 5-HT4 receptor agonists
目的 探讨应用莫沙必利对老年患者胶囊内镜检查中胃肠转运时间的影响. 方法 2010年9月至2012年1月间因疑似小肠疾病的患者61例,其中年龄≥65岁者40例,随机分为老年服药组19例和老年对照组21例,年龄＜65岁者21例为非老年对照组.服药组胶囊内镜检查前口服促胃肠动力药莫沙比利10 mg,记录胶囊内镜的胃肠通过时间. 结果 老年服药组胃及小肠通过时间分别为(48.6±21.1) min和(302.2±67.6) min,老年对照组分别为(64.3±22.4) min和(347.1±51.2) min,两组差异有统计学意义(t胃=2.274,P胃=0.029;t肠=2.384,P肠=0.022).非老年对照组胃及小肠通过时间分别为(45.4±28.4)min和(284.8±78.3)min,与老年服药组比较,差异无统计学意义(t胃=0.407,P胃=0.686;t肠=0.751,P肠=0.457).老年服药组和老年对照组图像评分分别为(4.94±0.63)分和(4.50±0.68)分,差异有统计学意义(t=2.137,P=0.039). 结论 老年患者胶囊内镜检查前口服莫沙必利药能缩短胶囊胃肠通过时间,改善胶囊镜的图像质量,提高检查完成率.
目的 探討應用莫沙必利對老年患者膠囊內鏡檢查中胃腸轉運時間的影響. 方法 2010年9月至2012年1月間因疑似小腸疾病的患者61例,其中年齡≥65歲者40例,隨機分為老年服藥組19例和老年對照組21例,年齡＜65歲者21例為非老年對照組.服藥組膠囊內鏡檢查前口服促胃腸動力藥莫沙比利10 mg,記錄膠囊內鏡的胃腸通過時間. 結果 老年服藥組胃及小腸通過時間分彆為(48.6±21.1) min和(302.2±67.6) min,老年對照組分彆為(64.3±22.4) min和(347.1±51.2) min,兩組差異有統計學意義(t胃=2.274,P胃=0.029;t腸=2.384,P腸=0.022).非老年對照組胃及小腸通過時間分彆為(45.4±28.4)min和(284.8±78.3)min,與老年服藥組比較,差異無統計學意義(t胃=0.407,P胃=0.686;t腸=0.751,P腸=0.457).老年服藥組和老年對照組圖像評分分彆為(4.94±0.63)分和(4.50±0.68)分,差異有統計學意義(t=2.137,P=0.039). 結論 老年患者膠囊內鏡檢查前口服莫沙必利藥能縮短膠囊胃腸通過時間,改善膠囊鏡的圖像質量,提高檢查完成率.
목적 탐토응용막사필리대노년환자효낭내경검사중위장전운시간적영향. 방법 2010년9월지2012년1월간인의사소장질병적환자61례,기중년령≥65세자40례,수궤분위노년복약조19례화노년대조조21례,년령＜65세자21례위비노년대조조.복약조효낭내경검사전구복촉위장동력약막사비리10 mg,기록효낭내경적위장통과시간. 결과 노년복약조위급소장통과시간분별위(48.6±21.1) min화(302.2±67.6) min,노년대조조분별위(64.3±22.4) min화(347.1±51.2) min,량조차이유통계학의의(t위=2.274,P위=0.029;t장=2.384,P장=0.022).비노년대조조위급소장통과시간분별위(45.4±28.4)min화(284.8±78.3)min,여노년복약조비교,차이무통계학의의(t위=0.407,P위=0.686;t장=0.751,P장=0.457).노년복약조화노년대조조도상평분분별위(4.94±0.63)분화(4.50±0.68)분,차이유통계학의의(t=2.137,P=0.039). 결론 노년환자효낭내경검사전구복막사필리약능축단효낭위장통과시간,개선효낭경적도상질량,제고검사완성솔.
Objective To explore the effect of oral mosapride on gastrointestinal transit time in elderly patients undergoing capsule endoscopy.Methods A total of 61 patients referred for capsule endoscopy during 2010 September to 2012 January were involved in this study.40 patients over 65 years old were prospectively randomized into mosapride citrate group (n=19) or non-mosapride citrate group (n=21).Patients under 65 years old were in control group (n=21).Mosapride citrate group took 10 mg mosapride citrate orally before endoscopy.The gastrointestinal transit time was calculated.Results Gastric emptying time and small intestinal transit time of patients over 65 years old were significantly shorter in mosapride citrate group than in non-mosapride citrate group [(48.6± 21.1) minand (64.3±22.4) min,t=2.274,P=0.029; (302.2±67.6) min vs.(347.14±51.18) min,t=2.384,P=0.022].There were on significant differences in gastric emptying time and small intestinal transit time between non-older group [(45.4 ± 28.4) min and (284.8 ± 78.3) min] and mosapride citrate group (t=0.407,P=0.686;t=0.751,P=0.457).There was a difference in the image score between medication group and no medication group (4.94±0.63 versus 4.50±0.68; t=2.137,P=0.039) in over 65 years old patients.Conclusions Mosapride may decreased the gastric emptying time and small intestinal transit time,improves the capsules endoscopy image quality and testing completion rate.
