中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
6期
612-614
,共3页
旃培艳%张临洪%徐武平%经屏
旃培豔%張臨洪%徐武平%經屏
전배염%장림홍%서무평%경병
脑缺血发作,短暂性%糖尿病%危险因素%预后
腦缺血髮作,短暫性%糖尿病%危險因素%預後
뇌결혈발작,단잠성%당뇨병%위험인소%예후
Ischemic attack,transient%Diabetes mellitus%Risk factor%Prognosis
目的 探讨糖尿病对老年短暂性脑缺血发作(TIA)短期卒中风险的影响. 方法 收集我科老年TIA住院患者,根据既往史及血糖、糖化血红蛋白结果将患者分为糖尿病组(31例)和无糖尿病组(95例),在首次短暂性脑缺血发作后30 d和90 d对患者进行随访,比较两组患者累计缺血性卒中事件发生率,分析短暂性脑缺血发作后短期卒中事件的危险因素. 结果 126例患者中糖尿病患者31例,占24.6％.30 d及90 d糖尿病组发生缺血性脑卒中比例明显高于无糖尿病组(54.8％比22.1％,61.3％比28.4％,P＜0.01).糖尿病组30 d、90 d累计卒中事件发生率均高于无糖尿病组糖尿病组在30 d、90 d的卒中风险增加了2.7倍及2.6倍.(P＜0.05).Cox回归多因素分析显示,糖尿病和脑动脉狭窄是90 d卒中事件的影响因素. 结论 合并糖尿病的老年短暂性脑缺血发作患者短期卒中事件发生率明显高于无糖尿病者,糖尿病是独立危险因素.
目的 探討糖尿病對老年短暫性腦缺血髮作(TIA)短期卒中風險的影響. 方法 收集我科老年TIA住院患者,根據既往史及血糖、糖化血紅蛋白結果將患者分為糖尿病組(31例)和無糖尿病組(95例),在首次短暫性腦缺血髮作後30 d和90 d對患者進行隨訪,比較兩組患者纍計缺血性卒中事件髮生率,分析短暫性腦缺血髮作後短期卒中事件的危險因素. 結果 126例患者中糖尿病患者31例,佔24.6％.30 d及90 d糖尿病組髮生缺血性腦卒中比例明顯高于無糖尿病組(54.8％比22.1％,61.3％比28.4％,P＜0.01).糖尿病組30 d、90 d纍計卒中事件髮生率均高于無糖尿病組糖尿病組在30 d、90 d的卒中風險增加瞭2.7倍及2.6倍.(P＜0.05).Cox迴歸多因素分析顯示,糖尿病和腦動脈狹窄是90 d卒中事件的影響因素. 結論 閤併糖尿病的老年短暫性腦缺血髮作患者短期卒中事件髮生率明顯高于無糖尿病者,糖尿病是獨立危險因素.
목적 탐토당뇨병대노년단잠성뇌결혈발작(TIA)단기졸중풍험적영향. 방법 수집아과노년TIA주원환자,근거기왕사급혈당、당화혈홍단백결과장환자분위당뇨병조(31례)화무당뇨병조(95례),재수차단잠성뇌결혈발작후30 d화90 d대환자진행수방,비교량조환자루계결혈성졸중사건발생솔,분석단잠성뇌결혈발작후단기졸중사건적위험인소. 결과 126례환자중당뇨병환자31례,점24.6％.30 d급90 d당뇨병조발생결혈성뇌졸중비례명현고우무당뇨병조(54.8％비22.1％,61.3％비28.4％,P＜0.01).당뇨병조30 d、90 d루계졸중사건발생솔균고우무당뇨병조당뇨병조재30 d、90 d적졸중풍험증가료2.7배급2.6배.(P＜0.05).Cox회귀다인소분석현시,당뇨병화뇌동맥협착시90 d졸중사건적영향인소. 결론 합병당뇨병적노년단잠성뇌결혈발작환자단기졸중사건발생솔명현고우무당뇨병자,당뇨병시독립위험인소.
Objective To investigate the effect of diabetes on short-term prognosis of transient ischemic attack (TIA) in elderly patients.Methods From January 2006 to June 2010,126 patients with TIA aged over 60 years were selected.Patients were divided into diabetic group and non-diabetic group according to past history,blood glucose and glycosylated hemoglobin levels.The cumulative ischemic stroke incidences were analyzed by Kaplan-Meier survival analysis 30 days and 90 days after the first TIA.The risk factors for short-term stroke after TIA were analyzed by Cox regression analysis.Results Among 126 patients with TIA,31 cases (24.6％) had diabetes.The cumulative ischemic stroke incidences were significantly higher in diabetic group than in non-diabetic group 30 days and 90 days after the first TIA (54.8％ vs.22.1％,61.3％ vs.28.4％,both P＜0.01).Cox regression analysis revealed that diabetes and cerebral arterial stenosis were the risk factors for recurrent stroke within 90 days.Conclusions The short-term stroke incidence is significantly higher in elderly diabetic patients than in non-diabetic patients.Diabetes is the independent risk factor for recurrent stroke after TIA.
