中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
6期
659-661
,共3页
邵军进%吕蕾%任祖华%吕金英
邵軍進%呂蕾%任祖華%呂金英
소군진%려뢰%임조화%려금영
二异丙酚%肌松弛药,中枢性%麻醉药,吸入
二異丙酚%肌鬆弛藥,中樞性%痳醉藥,吸入
이이병분%기송이약,중추성%마취약,흡입
Propofol%Muscle relaxants,central%Anestics,inhalation
目的 比较七氟烷与丙泊酚在同等麻醉深度时对老年患者顺式阿曲库铵肌松效应的影响. 方法 选择70例美国麻醉师协会(ASA)Ⅰ～Ⅱ级的60周岁以上老年患者,随机分为丙泊酚组和七氟烷组两组,每组35例.采用电刺激尺神经监测拇内收肌肌颤搐反应的方法进行肌松监测.两组分别采用丙泊酚和七氟烷进行麻醉诱导并比较两组顺式阿曲库铵在不同时间点注入速率和患者意识消失时间与顺式阿曲库铵肌松起效时间. 结果 吸入七氟烷后检测各时间点顺式阿曲库铵的注入速率,与未吸入前(即0 min)相比,分别下降了11.19％、29.82％、42.28％、37.15％.七氟烷组的注入速率在60 min之后下降较高,与丙泊酚组相比差异有统计学意义(P＜0.05).两组患者意识消失时间分别为(54.47±10.55)s和(53.89±11.48)s,差异无统计学意义(P＞0.05)；而顺式阿曲库铵肌松起效时间分别为(148.62±28.54)s和(96.53±23.69)s,七氟烷组起效时间短于丙泊酚组(P＜0.05). 结论 与丙泊酚比较,七氟烷能明显缩短顺式阿曲库铵的起效时间并延长顺式阿曲库铵的延长时效.
目的 比較七氟烷與丙泊酚在同等痳醉深度時對老年患者順式阿麯庫銨肌鬆效應的影響. 方法 選擇70例美國痳醉師協會(ASA)Ⅰ～Ⅱ級的60週歲以上老年患者,隨機分為丙泊酚組和七氟烷組兩組,每組35例.採用電刺激呎神經鑑測拇內收肌肌顫搐反應的方法進行肌鬆鑑測.兩組分彆採用丙泊酚和七氟烷進行痳醉誘導併比較兩組順式阿麯庫銨在不同時間點註入速率和患者意識消失時間與順式阿麯庫銨肌鬆起效時間. 結果 吸入七氟烷後檢測各時間點順式阿麯庫銨的註入速率,與未吸入前(即0 min)相比,分彆下降瞭11.19％、29.82％、42.28％、37.15％.七氟烷組的註入速率在60 min之後下降較高,與丙泊酚組相比差異有統計學意義(P＜0.05).兩組患者意識消失時間分彆為(54.47±10.55)s和(53.89±11.48)s,差異無統計學意義(P＞0.05)；而順式阿麯庫銨肌鬆起效時間分彆為(148.62±28.54)s和(96.53±23.69)s,七氟烷組起效時間短于丙泊酚組(P＜0.05). 結論 與丙泊酚比較,七氟烷能明顯縮短順式阿麯庫銨的起效時間併延長順式阿麯庫銨的延長時效.
목적 비교칠불완여병박분재동등마취심도시대노년환자순식아곡고안기송효응적영향. 방법 선택70례미국마취사협회(ASA)Ⅰ～Ⅱ급적60주세이상노년환자,수궤분위병박분조화칠불완조량조,매조35례.채용전자격척신경감측무내수기기전휵반응적방법진행기송감측.량조분별채용병박분화칠불완진행마취유도병비교량조순식아곡고안재불동시간점주입속솔화환자의식소실시간여순식아곡고안기송기효시간. 결과 흡입칠불완후검측각시간점순식아곡고안적주입속솔,여미흡입전(즉0 min)상비,분별하강료11.19％、29.82％、42.28％、37.15％.칠불완조적주입속솔재60 min지후하강교고,여병박분조상비차이유통계학의의(P＜0.05).량조환자의식소실시간분별위(54.47±10.55)s화(53.89±11.48)s,차이무통계학의의(P＞0.05)；이순식아곡고안기송기효시간분별위(148.62±28.54)s화(96.53±23.69)s,칠불완조기효시간단우병박분조(P＜0.05). 결론 여병박분비교,칠불완능명현축단순식아곡고안적기효시간병연장순식아곡고안적연장시효.
Objective To investigate the effect of propofol or sevoflurane on the quality of neuromuscular blockade with cisatracurium during comparable depth of anesthesia in elderly patients.Methods A total of 60 patients aged over 60 years [classified as American Society of Anesthesiologists (ASA) physical status Ⅰ-Ⅱ] were selected.Patients were randomized into 2 groups:propofol group (induction of anesthesia with propofol) and sevoflurane group (induction of anesthesia with sevoflurane) (n=35,each).Neuromuscular blocking effect was monitored by muscle response to ulnar nerve stimulation.The rates of cisatracurium injection at different time points,time of loss of consciousness and the onset time of cisatracurium neuromuscular block were compared between the two groups.Results The rate of cisatracurium injection was significantly decreased at 60 minutes,90 min,120 min in sevoflurane group(29.82％,42.28％,37.15％),and the onset time of cisatracurium neuromuscular block was significantly shorter in sevoflurane group than in propofol group [(148.62±28.54)s vs (96.53±23.69)s,P＜0.05].Conclusions Compared with propofol,sevoflurane can greatly shorten the onset time of cisatracurium and enhance the effect of cisatracurium neuromuscular block with stable hemodynamics.
