中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
9期
937-939
,共3页
高血压%白蛋白尿%肌酐
高血壓%白蛋白尿%肌酐
고혈압%백단백뇨%기항
Hypertension%Albuminuria%Creatinine
目的 探讨老年杓型高血压患者血压晨峰(morning blood pressure surge,MBPS)现象与尿微量白蛋白/肌酐(UmAlb/Cr)的关系. 方法 273例老年杓型高血压患者,根据动态血压监测有无MBPS现象分为晨峰组106例及非晨峰组167例,均进行UmAlb/Cr检测,并常规检测血尿素、肌酐、血糖、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油、胆固醇,分析两组间UmAlb/Cr差异. 结果 两组患者在性别比、年龄、高血压病程、血尿素、肌酐、血糖、HDL-C、LDL-C、三酰甘油、胆固醇比较差异均无统计学意义(P＞0.05).晨峰组与非晨峰组比较,MBPS变异幅度显著增高[(32.8±8.2)mm Hg比(12.0±7.2)mm Hg,P=0.00].晨峰组UmAlb/Cr高于非晨峰组(4.93±2.17比4.23±2.42,P=0.01),晨峰组不同性别UmAlb/Cr均高于非晨峰组(男性:4.95±1.96比2.98±2.05,P=0.001;女性:5.89±2.24比5.03±2.37,P=0.04). 结论 老年杓型高血压患者MBPS现象对UmAlb/Cr增高产生重要影响,有晨峰现象高血压患者易早期发生肾功能损害.
目的 探討老年杓型高血壓患者血壓晨峰(morning blood pressure surge,MBPS)現象與尿微量白蛋白/肌酐(UmAlb/Cr)的關繫. 方法 273例老年杓型高血壓患者,根據動態血壓鑑測有無MBPS現象分為晨峰組106例及非晨峰組167例,均進行UmAlb/Cr檢測,併常規檢測血尿素、肌酐、血糖、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)、三酰甘油、膽固醇,分析兩組間UmAlb/Cr差異. 結果 兩組患者在性彆比、年齡、高血壓病程、血尿素、肌酐、血糖、HDL-C、LDL-C、三酰甘油、膽固醇比較差異均無統計學意義(P＞0.05).晨峰組與非晨峰組比較,MBPS變異幅度顯著增高[(32.8±8.2)mm Hg比(12.0±7.2)mm Hg,P=0.00].晨峰組UmAlb/Cr高于非晨峰組(4.93±2.17比4.23±2.42,P=0.01),晨峰組不同性彆UmAlb/Cr均高于非晨峰組(男性:4.95±1.96比2.98±2.05,P=0.001;女性:5.89±2.24比5.03±2.37,P=0.04). 結論 老年杓型高血壓患者MBPS現象對UmAlb/Cr增高產生重要影響,有晨峰現象高血壓患者易早期髮生腎功能損害.
목적 탐토노년표형고혈압환자혈압신봉(morning blood pressure surge,MBPS)현상여뇨미량백단백/기항(UmAlb/Cr)적관계. 방법 273례노년표형고혈압환자,근거동태혈압감측유무MBPS현상분위신봉조106례급비신봉조167례,균진행UmAlb/Cr검측,병상규검측혈뇨소、기항、혈당、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)、삼선감유、담고순,분석량조간UmAlb/Cr차이. 결과 량조환자재성별비、년령、고혈압병정、혈뇨소、기항、혈당、HDL-C、LDL-C、삼선감유、담고순비교차이균무통계학의의(P＞0.05).신봉조여비신봉조비교,MBPS변이폭도현저증고[(32.8±8.2)mm Hg비(12.0±7.2)mm Hg,P=0.00].신봉조UmAlb/Cr고우비신봉조(4.93±2.17비4.23±2.42,P=0.01),신봉조불동성별UmAlb/Cr균고우비신봉조(남성:4.95±1.96비2.98±2.05,P=0.001;녀성:5.89±2.24비5.03±2.37,P=0.04). 결론 노년표형고혈압환자MBPS현상대UmAlb/Cr증고산생중요영향,유신봉현상고혈압환자역조기발생신공능손해.
Objective To investigate the relationship between morning blood pressure surge (MBPS) and urinary albumin/creatinine (UmAlb/Cr) ratio in elderly patients with dipper essential hypertension.Methods Totally 273 elderly patients with dipper essential hypertension were divided into MBPS group (observation group,n =106) and non MBPS group (control group,n=167)according to the presence or absence of MBPS.The urinary UmAlb/Cr ratio,blood urea nitrogen (BUN),creatinine (Cr),blood glucose (Glu),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),triglyceride (TG) and cholesterol (TCH) were detected.The differences in UmAlb/Cr ratio between the two groups were analyzed.Results There were no statistical significances in sex ratio,age,course of hypertension,BUN,Cr,blood Glu,HDL-C,LDL-C,TG and TCH between the two groups (P＞0.05).The amplitude of variation in morning systolic pressure peak was higher in MBPS group than in non-MBPS group [(32.8±8.2) mmHg vs.(12.0±7.2) mm Hg,P＜0.001].UmAlb/Cr ratio was higher in MBPS group than in non-MBPS group [(4.93±2.17) vs.(4.23±2.42),P＜0.05].There were significant differences in UmAlb/Cr ratio between MBPS group and non-MBPS group in different genders [male:(4.95± 1.96) vs.(2.98 ±2.05),female:(5.89±2.24) vs.(5.03±2.37),both P＜0.05].Conclusions MBPS has a great influence on UmAlb/Cr ratio and tends to cause early impairment of renal function in elderly patients with dipper essential hypertension.
