中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2009年
12期
1258-1260
,共3页
赵鑫%黄昕%黄鹏%张斯钰%陈婷%李林香%梁翠敏%文师吾%谭红专
趙鑫%黃昕%黃鵬%張斯鈺%陳婷%李林香%樑翠敏%文師吾%譚紅專
조흠%황흔%황붕%장사옥%진정%리림향%량취민%문사오%담홍전
慢性支气管炎%环境烟雾%家族史%交互作用
慢性支氣管炎%環境煙霧%傢族史%交互作用
만성지기관염%배경연무%가족사%교호작용
Chronic bronchitis%Environmental smoke%Family history%Interaction
目的 探讨湖南省浏阳市农村女性环境烟雾暴露及慢性支气管炎(慢支)家族史与慢支的关系,及二者之间的交互作用.方法 采用以人群为基础的病例对照研究方法,应用X2检验分析环境烟雾暴露及慢支家族史与慢支的关系,应用相加效应模型分析农村女性环境烟雾暴露与慢支家族史的交互作用.结果 在第一阶段对农村24 268名女性居民筛查中发现慢支患者157例(患病率6.47‰),第二阶段病例对照研究最终调查慢支患者92例,健康对照114人.结果 显示,使用煤炭/柴草取暖(OR=36.21)及慢支家族史(OR=6.41)可能是女性患慢支的危险因素(P<0.05);经常下厨及使用煤炭/柴草取暖与慢支家族史有明显的正交互作用,交互作用指数分别为5.39和9.02;交互作用归因危险比分别为72%和88%;交互作用相对超额危险度分别为6.50和225.99.结论 使用煤炭/柴草取暖和慢支家族史可能是女性慢支的危险因素,经常下厨、使用煤炭/柴草取暖与慢支家族史之间有正交互作用.
目的 探討湖南省瀏暘市農村女性環境煙霧暴露及慢性支氣管炎(慢支)傢族史與慢支的關繫,及二者之間的交互作用.方法 採用以人群為基礎的病例對照研究方法,應用X2檢驗分析環境煙霧暴露及慢支傢族史與慢支的關繫,應用相加效應模型分析農村女性環境煙霧暴露與慢支傢族史的交互作用.結果 在第一階段對農村24 268名女性居民篩查中髮現慢支患者157例(患病率6.47‰),第二階段病例對照研究最終調查慢支患者92例,健康對照114人.結果 顯示,使用煤炭/柴草取暖(OR=36.21)及慢支傢族史(OR=6.41)可能是女性患慢支的危險因素(P<0.05);經常下廚及使用煤炭/柴草取暖與慢支傢族史有明顯的正交互作用,交互作用指數分彆為5.39和9.02;交互作用歸因危險比分彆為72%和88%;交互作用相對超額危險度分彆為6.50和225.99.結論 使用煤炭/柴草取暖和慢支傢族史可能是女性慢支的危險因素,經常下廚、使用煤炭/柴草取暖與慢支傢族史之間有正交互作用.
목적 탐토호남성류양시농촌녀성배경연무폭로급만성지기관염(만지)가족사여만지적관계,급이자지간적교호작용.방법 채용이인군위기출적병례대조연구방법,응용X2검험분석배경연무폭로급만지가족사여만지적관계,응용상가효응모형분석농촌녀성배경연무폭로여만지가족사적교호작용.결과 재제일계단대농촌24 268명녀성거민사사중발현만지환자157례(환병솔6.47‰),제이계단병례대조연구최종조사만지환자92례,건강대조114인.결과 현시,사용매탄/시초취난(OR=36.21)급만지가족사(OR=6.41)가능시녀성환만지적위험인소(P<0.05);경상하주급사용매탄/시초취난여만지가족사유명현적정교호작용,교호작용지수분별위5.39화9.02;교호작용귀인위험비분별위72%화88%;교호작용상대초액위험도분별위6.50화225.99.결론 사용매탄/시초취난화만지가족사가능시녀성만지적위험인소,경상하주、사용매탄/시초취난여만지가족사지간유정교호작용.
Objective To explore the relationships and interaction among the exposure to environmental smoke,family history of chronic bronchitis(CB)and CB,in rural women.Methods A population-based case-control study χ~2 was used to analyze the relationship between environmental smoke exposure,CB family history and CB.Additive effects model was used to analyze the interaction.Results In the first stage,157 CB patients were screened from 24 268 women residents (prevalence rate is 6.47‰),then 92 patients(case group)and 114 healthy women(control group)were investigated in the second stage.Results showed that:coal/firewood for heating(OR=36.21)and CB family history(OR=6.41)might serve as the risk factors of CB in rural women(P<0.05).Factors as frequent cooking and using coal/firewood for heating had a positive interaction with family history of CB in rural women,CB with S as 5.39 and 9.02,attributable proportions of interaction (API)as 72% and 88%,relative excess risk of interaction(RERI)as 6.50 and 225.99,respectively.Conclusion Using coal/firewood for heating and CB family history might be the risk factors of CB for rural women.A positive interaction between cooking frequently,heating model and CB family history was also seen.