CAJ | 학술논문

目的探讨老年人髋部骨折与骨质疏松的相关性,并对结果进行验证.方法选取2009年1月至2012年3月唐山市工人医院收治的85例老年髋部骨折患者(髋部骨折组),测定其骨密度和尿液中生化标志物Ⅰ型胶原羟基末端肽、脱氧吡啶啉浓度,并选取60名非髋部骨折正常对照组进行对照检验.结果髋部骨折组骨密度显著低于正常对照组(P＜0.05),尿液Ⅰ型胶原羟基末端肽、脱氧吡啶啉的含量显著高于正常对照组,验证骨质疏松患者更易发生髋部骨折.结论老年髋部骨折多发于外伤,但骨密度和尿液Ⅰ型胶原羟基末端肽、脱氧吡啶啉的含量检测表明,骨质疏松是老年髋部骨折一个重要因素.
목적 탐토노년인관부골절여골질소송적상관성,병대결과진행험증.방법 선취2009년1월지2012년3월당산시공인의원수치적85례노년관부골절환자(관부골절조),측정기골밀도화뇨액중생화표지물Ⅰ형효원간기말단태、탈양필정람농도,병선취60명비관부골절정상대조조진행대조검험.결과 관부골절조골밀도현저저우정상대조조(P＜0.05),뇨액Ⅰ형효원간기말단태、탈양필정람적함량현저고우정상대조조,험증골질소송환자경역발생관부골절.결론 노년관부골절다발우외상,단골밀도화뇨액Ⅰ형효원간기말단태、탈양필정람적함량검측표명,골질소송시노년관부골절일개중요인소.
Objective To explore the relationship between elderly hip fracture and osteoporosis.Methods 85 elderly patients with hip fractures were admitted into our hospital from January 2009 to March 2012.Mineral density in bones and the concentration of biochemical markers Ⅰ collagen such as hydroxy terminal peptide (crosslaps) and deoxypyridinoline (DPD) in urine sample of the patients were measured.Another 60 non-hip fracture patients were selected as controls.Results Bone mineral density from the non-hip-fractured group appeared significantly higher than the hip-fractured group (P＜0.05),while the concentration of crosslaps and DPD in the urine of patients were significantly higher than the normal control group (P＜0.05),suggesting that the patients suffered from osteoporosis were more prone to hip fracture.Conclusion Although the hip fracture in the elderly was generally caused by trauma while factors as bone mineral density,concentration of crosslaps and DPD showed that osteoporosis played an important ‘internal’ role on hip fractures in the elderly.Attention should be paid to the elderly people with symptoms of osteoporosis and early treatment provided,to prevent hip fracture in this populaton.