中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
2期
140-142
,共3页
杜蔚云%裴凌云%马瑞兰%吴双%姜德民%马晴%李芝兰
杜蔚雲%裴凌雲%馬瑞蘭%吳雙%薑德民%馬晴%李芝蘭
두위운%배릉운%마서란%오쌍%강덕민%마청%리지란
先天缺陷%发生率%死亡率%三级预防
先天缺陷%髮生率%死亡率%三級預防
선천결함%발생솔%사망솔%삼급예방
Congenital defects%Incidence%Mortality%Three-grade prevention
目的 了解甘肃省5县(市)先天缺陷现状,为出生缺陷有效干预提供科学依据.方法 对甘肃省泾川县、徽县、渭源县、永靖县及敦煌市2009--2010统计年所有孕28周以上出生的新生儿(包括活产、死胎、死产)进行分析.结果 2009年甘肃省5县(市)先天缺陷发生率为7.49‰,居于前3位的先天缺陷病种分别为先天性心脏病、色素痣和四肢畸形；先天缺陷死亡率最高的是先天性心脏病(0.79‰).2010年先天缺陷发生率为8.35‰,居于前3位的先天缺陷病种分别为先天性心脏病、神经管畸形和色素痣、脑积水；先天缺陷死亡率最高的是先天性心脏病(1.10‰).5县(市)先天缺陷发生率不同,其中敦煌市先天缺陷发生率最高,为14.65‰,徽县最低,为3.28‰.结论 甘肃省5县(市)先天缺陷发生率不同,先天缺陷顺位发生改变,先天性心脏病取代神经管畸形成为发生顺位的第一位,应根据不同地区先天缺陷现状,优先解决该地区重点、突出的问题,通过三级预防措施降低先天缺陷的发生.
目的 瞭解甘肅省5縣(市)先天缺陷現狀,為齣生缺陷有效榦預提供科學依據.方法 對甘肅省涇川縣、徽縣、渭源縣、永靖縣及敦煌市2009--2010統計年所有孕28週以上齣生的新生兒(包括活產、死胎、死產)進行分析.結果 2009年甘肅省5縣(市)先天缺陷髮生率為7.49‰,居于前3位的先天缺陷病種分彆為先天性心髒病、色素痣和四肢畸形；先天缺陷死亡率最高的是先天性心髒病(0.79‰).2010年先天缺陷髮生率為8.35‰,居于前3位的先天缺陷病種分彆為先天性心髒病、神經管畸形和色素痣、腦積水；先天缺陷死亡率最高的是先天性心髒病(1.10‰).5縣(市)先天缺陷髮生率不同,其中敦煌市先天缺陷髮生率最高,為14.65‰,徽縣最低,為3.28‰.結論 甘肅省5縣(市)先天缺陷髮生率不同,先天缺陷順位髮生改變,先天性心髒病取代神經管畸形成為髮生順位的第一位,應根據不同地區先天缺陷現狀,優先解決該地區重點、突齣的問題,通過三級預防措施降低先天缺陷的髮生.
목적 료해감숙성5현(시)선천결함현상,위출생결함유효간예제공과학의거.방법 대감숙성경천현、휘현、위원현、영정현급돈황시2009--2010통계년소유잉28주이상출생적신생인(포괄활산、사태、사산)진행분석.결과 2009년감숙성5현(시)선천결함발생솔위7.49‰,거우전3위적선천결함병충분별위선천성심장병、색소지화사지기형；선천결함사망솔최고적시선천성심장병(0.79‰).2010년선천결함발생솔위8.35‰,거우전3위적선천결함병충분별위선천성심장병、신경관기형화색소지、뇌적수；선천결함사망솔최고적시선천성심장병(1.10‰).5현(시)선천결함발생솔불동,기중돈황시선천결함발생솔최고,위14.65‰,휘현최저,위3.28‰.결론 감숙성5현(시)선천결함발생솔불동,선천결함순위발생개변,선천성심장병취대신경관기형성위발생순위적제일위,응근거불동지구선천결함현상,우선해결해지구중점、돌출적문제,통과삼급예방조시강저선천결함적발생.
Objective To understand the situation of congenital defects' in five counties/cities in Gansu province so as to provide scientific evidence for the development of effective interventions.Methods General imformaton was collected on all the neonates who were born in Dunhuang city,Jingchuan county,Hui county,Weiyuan county and Yongjing county in Gansu province between Oct.1st,2009 to Sep.304th,2010,with all of their gestational age above 28 weeks.Neonates would include live birth,dead fetus and still birth.Results The overall incidence of congenital defects was 7.49‰ in the five counties/cities in Gansu province in 2009.Ranking order in the top three showed as congenital heart disease,pigmented nevus and limb deformity.Disease with the highest mortality was congenital heart disease (0.79‰).The incidence of congenital defects was 8.35‰ in 2010 with the ranking order of the top three as congenital heart disease,neural tube defects/pigmented nevus and hydrocephalus.Diseases having the highest mortality was congenital heart disease (1.10‰o).Different incidence rates on congenital defects were seen in realted areas,with the highest incidence as 14.65‰ in Dunhuang city.Hui county had the lowest incidence—3.28‰.Conclusion Different incidence of congenital defects were seen in respective areas in Gansu province,with the change of ranking orders.Different strategies should be developed differently depending on the current states of congenital defects in respective areas,according to the three-grade prevention model,to reduce the occurrence of congenital defects.
