CAJ | 학술논문

目的调查深圳市常住人口HBV感染情况及流行特征.方法 2010年采用多阶段分层随机抽样方法对深圳市罗湖区和宝安区1 ～ 59岁常住居民进行问卷调查,并采集静脉血,用ELISA检测乙型肝炎(乙肝)病毒表面抗原(HBsAg)和乙肝病毒表面抗体(抗-HBs).结果 3771人中,HBsAg阳性252例,标化阳性率为9.73％;抗-HBs阳性2712例,标化阳性率为72.83％.HBsAg阳性率随年龄增长呈升高趋势(P＜0.05);深圳市户籍与非深圳市户籍居民HBsAg阳性率差异无统计学意义(P＞0.05),但深圳市户籍人口抗-HBs阳性率(78.32％)高于非深圳市户籍人群(66.03％),差异有统计学意义(x2=41.613,P＜0.001);HBsAg阳性率在不同职业人群中差异较大,其中农民最高,达24.13％,抗-HBs阳性率中医护人员最高(89.10％);初中文化程度人群HBsAg阳性率最高(12.76％),大专及以上文化程度人群抗-HBs阳性率最高,平均为81.00％,而初中水平人群抗-HBs阳性率最低,仅为62.45％;出生地为广东、深圳地区的调查人群HBsAg阳性率均超过10％,抗-HBs阳性率以深圳和广东地区出生人群最高,分别为74.48％和76.47％.结论深圳市乙肝感染低于广东省,但高于全国平均水平.
목적 조사심수시상주인구HBV감염정황급류행특정.방법 2010년채용다계단분층수궤추양방법대심수시라호구화보안구1 ～ 59세상주거민진행문권조사,병채집정맥혈,용ELISA검측을형간염(을간)병독표면항원(HBsAg)화을간병독표면항체(항-HBs).결과 3771인중,HBsAg양성252례,표화양성솔위9.73％;항-HBs양성2712례,표화양성솔위72.83％.HBsAg양성솔수년령증장정승고추세(P＜0.05);심수시호적여비심수시호적거민HBsAg양성솔차이무통계학의의(P＞0.05),단심수시호적인구항-HBs양성솔(78.32％)고우비심수시호적인군(66.03％),차이유통계학의의(x2=41.613,P＜0.001);HBsAg양성솔재불동직업인군중차이교대,기중농민최고,체24.13％,항-HBs양성솔중의호인원최고(89.10％);초중문화정도인군HBsAg양성솔최고(12.76％),대전급이상문화정도인군항-HBs양성솔최고,평균위81.00％,이초중수평인군항-HBs양성솔최저,부위62.45％;출생지위엄동、심수지구적조사인군HBsAg양성솔균초과10％,항-HBs양성솔이심수화엄동지구출생인군최고,분별위74.48％화76.47％.결론 심수시을간감염저우광동성,단고우전국평균수평.
Objective To understand the infection status and epidemiological features of HBV in permanent residents of Shenzhen city.Methods A multi-stage stratified random sampling method was performed for questionnaire survey to permanently-registered residents of 1-59 years old in Luohu and Baoan district of Shenzhen in 2010,and blood samples of the subjects were collected.Hepatitis B virus-related surface antigen (HBsAg) and hepatitis B virus surface antibody (anti-HBs)were detected with ELISA.Results The total 3771 studied population showed 252 HBsAg positive and 2712 anfi-HBs positive residents with the standardization prevalence as 9.73％ and 72.83％,respectively.The difference of the prevalence of HBsAg and anti-HBs between males and females were not statistically significant (P＞ 0.05).The prevalence of HBsAg was reduced with increasing age.The differences of the prevalence of HBsAg between Shenzhen permanent registered and non-permanent registered population were not significant,but the prevalence of anti-HBs in Permanent registered residents (78.32％) was higher than in non-permanent (66.03％,x2 =41.613,P＜0.001).The prevalence of HBsAg was significantly different in various occupational and educational levels.Peasants had the highest prevalence (24.13％)and medical workers had the highest prevalence of anti-HBs (89.10％).People with junior high school education had the highest prevalence of HBsAg (12.76％) and the lowest of anti-HBs (62.45％).Population with high-level education had the highest prevalence of anti-HBs (81.00％ average).The prevalence of HBsAg was over 10％ in people who were born in Shenzhen and Guangdong province,and the anti-HBs was the highest in Shenzhen population with the prevalence as 74.48％ and 76.47％,respectively.Conclusion In the Shenzhen resident population,the overall prevalence of HBV was lower than the average level of Guangdong province,but higher than the national wide.