中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2013年
12期
1179-1182
,共4页
程锦泉%马汉武%谢旭%路滟%张艳彪%董书贤%王廷哲%刘益民%凌文华
程錦泉%馬漢武%謝旭%路滟%張豔彪%董書賢%王廷哲%劉益民%凌文華
정금천%마한무%사욱%로염%장염표%동서현%왕정철%류익민%릉문화
乙型肝炎%流行病学
乙型肝炎%流行病學
을형간염%류행병학
Hepatitis B%Epidemiology
目的 调查深圳市常住人口HBV感染情况及流行特征.方法 2010年采用多阶段分层随机抽样方法对深圳市罗湖区和宝安区1 ~ 59岁常住居民进行问卷调查,并采集静脉血,用ELISA检测乙型肝炎(乙肝)病毒表面抗原(HBsAg)和乙肝病毒表面抗体(抗-HBs).结果 3771人中,HBsAg阳性252例,标化阳性率为9.73%;抗-HBs阳性2712例,标化阳性率为72.83%.HBsAg阳性率随年龄增长呈升高趋势(P<0.05);深圳市户籍与非深圳市户籍居民HBsAg阳性率差异无统计学意义(P>0.05),但深圳市户籍人口抗-HBs阳性率(78.32%)高于非深圳市户籍人群(66.03%),差异有统计学意义(x2=41.613,P<0.001);HBsAg阳性率在不同职业人群中差异较大,其中农民最高,达24.13%,抗-HBs阳性率中医护人员最高(89.10%);初中文化程度人群HBsAg阳性率最高(12.76%),大专及以上文化程度人群抗-HBs阳性率最高,平均为81.00%,而初中水平人群抗-HBs阳性率最低,仅为62.45%;出生地为广东、深圳地区的调查人群HBsAg阳性率均超过10%,抗-HBs阳性率以深圳和广东地区出生人群最高,分别为74.48%和76.47%.结论 深圳市乙肝感染低于广东省,但高于全国平均水平.
目的 調查深圳市常住人口HBV感染情況及流行特徵.方法 2010年採用多階段分層隨機抽樣方法對深圳市囉湖區和寶安區1 ~ 59歲常住居民進行問捲調查,併採集靜脈血,用ELISA檢測乙型肝炎(乙肝)病毒錶麵抗原(HBsAg)和乙肝病毒錶麵抗體(抗-HBs).結果 3771人中,HBsAg暘性252例,標化暘性率為9.73%;抗-HBs暘性2712例,標化暘性率為72.83%.HBsAg暘性率隨年齡增長呈升高趨勢(P<0.05);深圳市戶籍與非深圳市戶籍居民HBsAg暘性率差異無統計學意義(P>0.05),但深圳市戶籍人口抗-HBs暘性率(78.32%)高于非深圳市戶籍人群(66.03%),差異有統計學意義(x2=41.613,P<0.001);HBsAg暘性率在不同職業人群中差異較大,其中農民最高,達24.13%,抗-HBs暘性率中醫護人員最高(89.10%);初中文化程度人群HBsAg暘性率最高(12.76%),大專及以上文化程度人群抗-HBs暘性率最高,平均為81.00%,而初中水平人群抗-HBs暘性率最低,僅為62.45%;齣生地為廣東、深圳地區的調查人群HBsAg暘性率均超過10%,抗-HBs暘性率以深圳和廣東地區齣生人群最高,分彆為74.48%和76.47%.結論 深圳市乙肝感染低于廣東省,但高于全國平均水平.
목적 조사심수시상주인구HBV감염정황급류행특정.방법 2010년채용다계단분층수궤추양방법대심수시라호구화보안구1 ~ 59세상주거민진행문권조사,병채집정맥혈,용ELISA검측을형간염(을간)병독표면항원(HBsAg)화을간병독표면항체(항-HBs).결과 3771인중,HBsAg양성252례,표화양성솔위9.73%;항-HBs양성2712례,표화양성솔위72.83%.HBsAg양성솔수년령증장정승고추세(P<0.05);심수시호적여비심수시호적거민HBsAg양성솔차이무통계학의의(P>0.05),단심수시호적인구항-HBs양성솔(78.32%)고우비심수시호적인군(66.03%),차이유통계학의의(x2=41.613,P<0.001);HBsAg양성솔재불동직업인군중차이교대,기중농민최고,체24.13%,항-HBs양성솔중의호인원최고(89.10%);초중문화정도인군HBsAg양성솔최고(12.76%),대전급이상문화정도인군항-HBs양성솔최고,평균위81.00%,이초중수평인군항-HBs양성솔최저,부위62.45%;출생지위엄동、심수지구적조사인군HBsAg양성솔균초과10%,항-HBs양성솔이심수화엄동지구출생인군최고,분별위74.48%화76.47%.결론 심수시을간감염저우광동성,단고우전국평균수평.
Objective To understand the infection status and epidemiological features of HBV in permanent residents of Shenzhen city.Methods A multi-stage stratified random sampling method was performed for questionnaire survey to permanently-registered residents of 1-59 years old in Luohu and Baoan district of Shenzhen in 2010,and blood samples of the subjects were collected.Hepatitis B virus-related surface antigen (HBsAg) and hepatitis B virus surface antibody (anti-HBs)were detected with ELISA.Results The total 3771 studied population showed 252 HBsAg positive and 2712 anfi-HBs positive residents with the standardization prevalence as 9.73% and 72.83%,respectively.The difference of the prevalence of HBsAg and anti-HBs between males and females were not statistically significant (P> 0.05).The prevalence of HBsAg was reduced with increasing age.The differences of the prevalence of HBsAg between Shenzhen permanent registered and non-permanent registered population were not significant,but the prevalence of anti-HBs in Permanent registered residents (78.32%) was higher than in non-permanent (66.03%,x2 =41.613,P<0.001).The prevalence of HBsAg was significantly different in various occupational and educational levels.Peasants had the highest prevalence (24.13%)and medical workers had the highest prevalence of anti-HBs (89.10%).People with junior high school education had the highest prevalence of HBsAg (12.76%) and the lowest of anti-HBs (62.45%).Population with high-level education had the highest prevalence of anti-HBs (81.00% average).The prevalence of HBsAg was over 10% in people who were born in Shenzhen and Guangdong province,and the anti-HBs was the highest in Shenzhen population with the prevalence as 74.48% and 76.47%,respectively.Conclusion In the Shenzhen resident population,the overall prevalence of HBV was lower than the average level of Guangdong province,but higher than the national wide.