CAJ | 학술논문

目的描述1996-2010年北京市多胎妊娠变化趋势,比较单胎和多胎妊娠产妇妊娠并发症发生率的差异.方法以1996-2000、2005和2010年北京妇产医院和北京市海淀区妇幼保健院分娩的活产儿为研究对象,采用病例回顾分析的方法进行分析.采集项目包括产妇年龄、胎数、分娩方式、是否患有妊娠高血压、妊娠糖尿病、妊娠贫血、新生儿性别、出生体重、孕周等.出生体重及率的趋势分析采用线性回归直线拟合来评价.组间率的比较采用x2检验.结果研究对象包括63 661名活产新生儿和62 895名产妇(其中单胎产妇62 135名,多胎妊娠且胎儿均为活产产妇751名).1996-2010年多胎妊娠发生率呈增加趋势,平均每年增加0.02％(P＜0.05)；多胎妊娠剖宫产率平均每年增加2.25％(P＜0.01)；15年来多胎和单胎新生儿出生体重总体变化趋势不明显,2000年以前单胎儿出生体重呈增加趋势,平均每年增加23.7 g(P＜0.001);低出生体重发生率变化不明显；早产发生率多胎儿平均每年增加1.62％(P＜0.05),单胎儿略呈增加趋势,平均每年增加0.16％(P＜0.05).此期间单胎儿平均出生体重为＞3 250 g,多胎儿＜2 500 g；多胎儿低出生体重率和早产率显著高于单胎儿；多胎妊娠产妇的剖宫产率明显高于单胎产妇.多胎妊娠产妇的妊娠高血压、妊娠贫血的发生率(44％和11.2％)明显高于单胎妊娠产妇(12.8％和23.2％),妊娠糖尿病发生率差异无统计学意义.结论 1995-2010年北京市多胎妊娠率明显增加.多胎妊娠产妇较之单胎妊娠产妇更易于发生妊娠高血压、妊娠贫血.
목적 묘술1996-2010년북경시다태임신변화추세,비교단태화다태임신산부임신병발증발생솔적차이.방법 이1996-2000、2005화2010년북경부산의원화북경시해정구부유보건원분면적활산인위연구대상,채용병례회고분석적방법진행분석.채집항목포괄산부년령、태수、분면방식、시부환유임신고혈압、임신당뇨병、임신빈혈、신생인성별、출생체중、잉주등.출생체중급솔적추세분석채용선성회귀직선의합래평개.조간솔적비교채용x2검험.결과 연구대상포괄63 661명활산신생인화62 895명산부(기중단태산부62 135명,다태임신차태인균위활산산부751명).1996-2010년다태임신발생솔정증가추세,평균매년증가0.02％(P＜0.05)；다태임신부궁산솔평균매년증가2.25％(P＜0.01)；15년래다태화단태신생인출생체중총체변화추세불명현,2000년이전단태인출생체중정증가추세,평균매년증가23.7 g(P＜0.001);저출생체중발생솔변화불명현；조산발생솔다태인평균매년증가1.62％(P＜0.05),단태인략정증가추세,평균매년증가0.16％(P＜0.05).차기간단태인평균출생체중위＞3 250 g,다태인＜2 500 g；다태인저출생체중솔화조산솔현저고우단태인；다태임신산부적부궁산솔명현고우단태산부.다태임신산부적임신고혈압、임신빈혈적발생솔(44％화11.2％)명현고우단태임신산부(12.8％화23.2％),임신당뇨병발생솔차이무통계학의의.결론 1995-2010년북경시다태임신솔명현증가.다태임신산부교지단태임신산부경역우발생임신고혈압、임신빈혈.
Objective To describe the trend of multiple pregnancies and to compare the results with single pregnancy in Beijing from 1996 to 2010.Prevalence rates of pregnancy complications were compared between multiple and single pregnancies.Methods In 1996,1997,1998,1999,2000,2005,2010,live births in two hospitals in Beijing were included to describe the trend of multiple and single pregnancy.Case-retrospective analyses were used.Information was collected,including maternal age,fetus number,delivery mode,with/without pregnancy induced diseases as hypertension,diabetes or anemia,gender of the baby,birth-weight and gestation etc.Linear regression analyses were applied to assess the trend of birth-weight and the rates of prevalence.Results 63 661 babies and 62 895 puerperal were involved in this study.From 1996 to 2010,prevalence of multiple pregnancies increased by 0.02％,prevalence of cesarean delivery among multiple pregnancy women increased by 2.25％ and the proportion of women older than 30 years increased by 3.52％ and 2.89％ among multiple or single pregnancy women,annually.However,the birth-weight did not show obvious change in both multiple and single birth babies.No obvious change was observed in the prevalence of low birth weight.Prevalence rates of premature birth increased by 1.62％ and 0.16％ among multiple and single pregnancy women,annually.From 1996 to 2010,the mean values of birth-weight among single birth babies were larger than 3 250 grams and under 2 500 gram among multiple birth babies.Rates of prevalence on pregnancy induced hypertension and anemia were higher in multiple pregnancy women than in single pregnancy women.Differences of rates on prevalence rates of pregnancy diabetes between multiple and single pregnancy women were not statistically significant.Conclusion Prevalence of multiple pregnancies increased from 1995 to 2010 in Beijing.Mothers of multiples were more likely to get pregnancy complication than the single pregnancy women.