CAJ | 학술논문

目的分析成都市某医院一起扁桃体炎暴发疫情的原因、传播途径及危险因素.方法采用病例对照研究进行现场流行病学调查,利用自制问卷面对面调查收集可能的危险因素,通过非条件logistic回归方法进行单因素和多因素分析.结果该次疫情共发病74例,以20 ～ 30岁青壮年为主,女性多于男性,集中在8月20-22日发病,且均为医院员工,以医生和护士为主,无住院患者发病.患者空间分布以手术室、麻醉科和外科相关科室居多(71.62％,53/74),其中39.19％ (29/74)分布于手术室和麻醉科.logistic回归分析显示,8月19日进入配餐间午餐为暴露的危险因素(OR=6.67,95％CI:1.92～23.23).采集患者咽拭子细菌培养分离出β溶血性链球菌.结论该次疫情为一起β溶血性链球菌感染引起医院内急性扁桃体炎暴发,8月19日进入配餐间午餐为暴发疫情的危险因素,不排除食源性和飞沫途径传播.
목적 분석성도시모의원일기편도체염폭발역정적원인、전파도경급위험인소.방법 채용병례대조연구진행현장류행병학조사,이용자제문권면대면조사수집가능적위험인소,통과비조건logistic회귀방법진행단인소화다인소분석.결과 해차역정공발병74례,이20 ～ 30세청장년위주,녀성다우남성,집중재8월20-22일발병,차균위의원원공,이의생화호사위주,무주원환자발병.환자공간분포이수술실、마취과화외과상관과실거다(71.62％,53/74),기중39.19％ (29/74)분포우수술실화마취과.logistic회귀분석현시,8월19일진입배찬간오찬위폭로적위험인소(OR=6.67,95％CI:1.92～23.23).채집환자인식자세균배양분리출β용혈성련구균.결론 해차역정위일기β용혈성련구균감염인기의원내급성편도체염폭발,8월19일진입배찬간오찬위폭발역정적위험인소,불배제식원성화비말도경전파.
Objective To investigate an outbreak of beta-hemolytic streptococcal tonsillitis in a hospital.Methods A case-control study was conducted with a self-made questionnaire to collect the risk factors.Univariate and multivariate logistic regression model were used to explore the relationship between risk factors and morbidity.Results 74 cases were occurred during the outbreak with patients aged mainly between 20-30 and more females than males.Most cases appeared abrupt onset between Aug.,20-22.All the patients were hospital workers,with majority as nurses and doctors from the operating room,department of anesthesiology and surgical related departments (71.62％).All patients shared the same experience-eating lunch in the dining room on Aug 19 (odds ratio 6.67,95％ confidence interval 1.92-23.23).Beta-hemolytic streptococci was observed from cultures of the throats from the patients.Conclusion The outbreak was an explosive epidemic of tonsillitis in a hospital,caused by beta-hemolytic streptococci.Food provided from the dining room attached to the operating theater on August,19 seemed to be the risk factor.