中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2014年
7期
784-786
,共3页
高欣%段春波%鲍利%于会艳%秦斌%齐若梅%高芳堃
高訢%段春波%鮑利%于會豔%秦斌%齊若梅%高芳堃
고흔%단춘파%포리%우회염%진빈%제약매%고방곤
糖尿病,2型%高血压%认知功能%老年人
糖尿病,2型%高血壓%認知功能%老年人
당뇨병,2형%고혈압%인지공능%노년인
Diabetes mellitus,type 2%Hypertension%Cognition%Elderly
目的 了解社区老年糖尿病患者合并高血压对其认知功能的影响.方法 选择北京市某社区＞60岁老年糖尿病患者82例和糖尿病合并高血压患者142例为调查对象,同社区年龄、性别及文化程度相匹配的277名正常老年人为对照,以简易智能状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)评估三组人群的认知功能状况.结果 糖尿病合并高血压患者组较正常对照组MMSE总分降低(28.42±1.52 vs.28.88±1.47),差异有统计学意义(P＜0.05);糖尿病合并高血压患者组与正常对照组比较,MoCA总得分(25.20±3.91 vs.26.50±3.29)、视空间与执行功能(3.60±1.56 vs.3.96±1.18)和语言得分(2.10±0.80 vs.2.37±0.80)明显降低,差异有统计学意义(P＜0.05).多元回归分析显示,高龄、受教育程度低是认知障碍的独立危险因素(P＜0.01).结论老年糖尿病患者合并高血压可导致认知功能受损.
目的 瞭解社區老年糖尿病患者閤併高血壓對其認知功能的影響.方法 選擇北京市某社區＞60歲老年糖尿病患者82例和糖尿病閤併高血壓患者142例為調查對象,同社區年齡、性彆及文化程度相匹配的277名正常老年人為對照,以簡易智能狀態檢查量錶(MMSE)和矇特利爾認知評估量錶(MoCA)評估三組人群的認知功能狀況.結果 糖尿病閤併高血壓患者組較正常對照組MMSE總分降低(28.42±1.52 vs.28.88±1.47),差異有統計學意義(P＜0.05);糖尿病閤併高血壓患者組與正常對照組比較,MoCA總得分(25.20±3.91 vs.26.50±3.29)、視空間與執行功能(3.60±1.56 vs.3.96±1.18)和語言得分(2.10±0.80 vs.2.37±0.80)明顯降低,差異有統計學意義(P＜0.05).多元迴歸分析顯示,高齡、受教育程度低是認知障礙的獨立危險因素(P＜0.01).結論老年糖尿病患者閤併高血壓可導緻認知功能受損.
목적 료해사구노년당뇨병환자합병고혈압대기인지공능적영향.방법 선택북경시모사구＞60세노년당뇨병환자82례화당뇨병합병고혈압환자142례위조사대상,동사구년령、성별급문화정도상필배적277명정상노년인위대조,이간역지능상태검사량표(MMSE)화몽특리이인지평고량표(MoCA)평고삼조인군적인지공능상황.결과 당뇨병합병고혈압환자조교정상대조조MMSE총분강저(28.42±1.52 vs.28.88±1.47),차이유통계학의의(P＜0.05);당뇨병합병고혈압환자조여정상대조조비교,MoCA총득분(25.20±3.91 vs.26.50±3.29)、시공간여집행공능(3.60±1.56 vs.3.96±1.18)화어언득분(2.10±0.80 vs.2.37±0.80)명현강저,차이유통계학의의(P＜0.05).다원회귀분석현시,고령、수교육정도저시인지장애적독립위험인소(P＜0.01).결론노년당뇨병환자합병고혈압가도치인지공능수손.
Objective To study the effects of type 2 diabetes (T2DM) with hypertension on cognitive function in those community-based elderly who were aged 60 and over,in Beijing.Methods 82 patients with T2DM,142 patients with both T2DM and hypertension and 277 normal controls were investigated in this study.Both methods as:the Montreal Cognitive Assessment (MoCA) and Mini-Mental Status Examination (MMSE) were used to determine cognitive change.Results The total MMSE scores showed significant decrease between T2DM with hypertension and controls [(28.42± 1.52) vs.(28.88± 1.47),P＜0.05].The MoCA score of the total scores [(25.20± 3.91) vs.(26.50 ± 3.29),P＜0.05],sub-scores of visuospatial,executive [(3.60± 1.56) vs.(3.96± 1.18),P＜0.05] and language [(2.10± 0.80) vs.(2.37± 0.80),P＜0.05] significantly decreased in T2DM patients with hypertension and in the normal controls.Data from the Multiple logistic regression analysis showed that older age and less education were risk factors for cognitive impairment.Conclusion T2DM and hypertension damaged the cognitive function of patients.
