CAJ | 학술논문

目的探讨新疆哈萨克族成年人群最适WHR切点值对筛选心血管疾病高危人群的作用.方法 2007年10月至2010年3月开展新疆地区心血管风险调查(CRS),共选择具有代表性样本14 618人,其中哈萨克族4 094人,从中选取资料完整的4 004人作为研究对象,年龄35 ～ 88岁,平均48.60岁.测量并记录每名入组对象的血压、TC、TG、LDL-C、HDL-C和FPG.计算并记录不同WHR值所对应的心血管疾病危险因素的患病率、敏感度、特异度及在受试者工作特征(ROC)曲线上的距离.结果 (1)无论男性和女性,WHR值较高人群其高血压和高TG血症的患病率较高;(2)WHR值较高的女性,其高TC血症的患病率较高;(3)无论男性和女性,其高血压、血脂异常、糖尿病或≥2个危险因素在ROC曲线上的最短距离定为最适WHR切点值,男性为0.92和0.91,女性为0.86和0.85.结论在≥35岁哈萨克族成年人群中需要采用较高的WHR切点值筛查心血管疾病风险人群.
목적 탐토신강합살극족성년인군최괄WHR절점치대사선심혈관질병고위인군적작용.방법 2007년10월지2010년3월개전신강지구심혈관풍험조사(CRS),공선택구유대표성양본14 618인,기중합살극족4 094인,종중선취자료완정적4 004인작위연구대상,년령35 ～ 88세,평균48.60세.측량병기록매명입조대상적혈압、TC、TG、LDL-C、HDL-C화FPG.계산병기록불동WHR치소대응적심혈관질병위험인소적환병솔、민감도、특이도급재수시자공작특정(ROC)곡선상적거리.결과 (1)무론남성화녀성,WHR치교고인군기고혈압화고TG혈증적환병솔교고;(2)WHR치교고적녀성,기고TC혈증적환병솔교고;(3)무론남성화녀성,기고혈압、혈지이상、당뇨병혹≥2개위험인소재ROC곡선상적최단거리정위최괄WHR절점치,남성위0.92화0.91,녀성위0.86화0.85.결론 재≥35세합살극족성년인군중수요채용교고적WHR절점치사사심혈관질병풍험인군.
Objective The aim of this study was to identify the appropriate cutoffs for waist-hip-ratio (WHR) for Kazakh adults at high risk of cardiovascular diseases in Xinjiang.Methods A Cardiovascular Risk Survey (CRS) study was carried out from October 2007 to March 2010,with 14 618 representative participants selected,including 4 094 Kazakhs.Complete data on 4 004 participants were gathered.The age span of the participants was from 35 to 88 years old with the mean age as 48.60 years.Anthropometric data,blood pressure,serum concentration of serum total cholesterol,triglyceride,low density lipoprotein cholesterol (LDL-C),high density lipoprotein cholesterol (HDL-C) and fasting glucose were documented.Prevalence rate,sensitivity,specificity and distance on the receiver operating characteristic (ROC) curve of each WHR values were calculated.Results 1) The prevalence rates of hypertension,hypertriglyeeridemia were high,also with higher WHR seen in both men and women.2) The prevalence of hypercholesterolemia was high with higher WHR seen in women.3) The shortest distances in the receiver operating characteristic curves for hypertension,dyslipidemia,diabetes,or ≥2 of these risk factors suggested that the WHR cutoffs were 0.92 or 0.91 for men and 0.86 or 0.85 for women.Conclusion Higher cutoff for WHR was needed in the identification of patients over 35 at high risk of cardiovascular disease among Kazakh population.