中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2014年
9期
1053-1057
,共5页
黄宇玲%王志军%刘雪梅%李雯%王迈%陈朔华%吴寿岭
黃宇玲%王誌軍%劉雪梅%李雯%王邁%陳朔華%吳壽嶺
황우령%왕지군%류설매%리문%왕매%진삭화%오수령
高静息心率%颈动脉斑块%中老年人群%危险因素
高靜息心率%頸動脈斑塊%中老年人群%危險因素
고정식심솔%경동맥반괴%중노년인군%위험인소
High resting heart rate%Carotid artery plaque%Elderly population%Risk factors
目的 探讨中老年人群高静息心率对颈动脉斑块检出率的影响.方法 2010年6月至2011年6月在健康体检职工中随机分层抽取5 852人作为观察对象,进行统一血液生化、静息心率及颈动脉超声检查,其中5 440人符合人选标准,最后有5 280人纳入统计分析,根据静息心率水平分为≤80次/分(低静息心率组)和＞80次/分(高静息心率组),比较性别、年龄分层后颈动脉斑块的检出率,采用单因素和多因素logistic回归分析颈动脉斑块的影响因素.结果 (1)高静息心率组颈动脉斑块检出率高于低静息心率组(48.9％vs.41.5％,P＜0.001);按性别分层后,男性高、低静息心率组颈动脉斑块检出率分别为58.7％和52.1％,女性分别为26.9％和25.1％.(2)随着年龄增长,颈动脉斑块检出率逐渐升高,年龄＜50、50～、60～、≥70岁人群颈动脉斑块检出率分别为19.5％、42.9％、67.6％、86.5％,高静息心率组颈动脉斑块检出率分别为25.1％、50.0％、70.5％、87.5％,低静息心率组颈动脉斑块检出率分别为18.5％、41.8％、60.7％、86.3％.(3)校正影响颈动脉斑块的多因素logistic回归分析,显示高静息心率组发生颈动脉斑块的风险比低静息心率组增加22.6％(OR=1.226,95％CI:1.018 ～ 1.477).结论 高静息心率能增加颈动脉斑块的发生风险.
目的 探討中老年人群高靜息心率對頸動脈斑塊檢齣率的影響.方法 2010年6月至2011年6月在健康體檢職工中隨機分層抽取5 852人作為觀察對象,進行統一血液生化、靜息心率及頸動脈超聲檢查,其中5 440人符閤人選標準,最後有5 280人納入統計分析,根據靜息心率水平分為≤80次/分(低靜息心率組)和＞80次/分(高靜息心率組),比較性彆、年齡分層後頸動脈斑塊的檢齣率,採用單因素和多因素logistic迴歸分析頸動脈斑塊的影響因素.結果 (1)高靜息心率組頸動脈斑塊檢齣率高于低靜息心率組(48.9％vs.41.5％,P＜0.001);按性彆分層後,男性高、低靜息心率組頸動脈斑塊檢齣率分彆為58.7％和52.1％,女性分彆為26.9％和25.1％.(2)隨著年齡增長,頸動脈斑塊檢齣率逐漸升高,年齡＜50、50～、60～、≥70歲人群頸動脈斑塊檢齣率分彆為19.5％、42.9％、67.6％、86.5％,高靜息心率組頸動脈斑塊檢齣率分彆為25.1％、50.0％、70.5％、87.5％,低靜息心率組頸動脈斑塊檢齣率分彆為18.5％、41.8％、60.7％、86.3％.(3)校正影響頸動脈斑塊的多因素logistic迴歸分析,顯示高靜息心率組髮生頸動脈斑塊的風險比低靜息心率組增加22.6％(OR=1.226,95％CI:1.018 ～ 1.477).結論 高靜息心率能增加頸動脈斑塊的髮生風險.
목적 탐토중노년인군고정식심솔대경동맥반괴검출솔적영향.방법 2010년6월지2011년6월재건강체검직공중수궤분층추취5 852인작위관찰대상,진행통일혈액생화、정식심솔급경동맥초성검사,기중5 440인부합인선표준,최후유5 280인납입통계분석,근거정식심솔수평분위≤80차/분(저정식심솔조)화＞80차/분(고정식심솔조),비교성별、년령분층후경동맥반괴적검출솔,채용단인소화다인소logistic회귀분석경동맥반괴적영향인소.결과 (1)고정식심솔조경동맥반괴검출솔고우저정식심솔조(48.9％vs.41.5％,P＜0.001);안성별분층후,남성고、저정식심솔조경동맥반괴검출솔분별위58.7％화52.1％,녀성분별위26.9％화25.1％.(2)수착년령증장,경동맥반괴검출솔축점승고,년령＜50、50～、60～、≥70세인군경동맥반괴검출솔분별위19.5％、42.9％、67.6％、86.5％,고정식심솔조경동맥반괴검출솔분별위25.1％、50.0％、70.5％、87.5％,저정식심솔조경동맥반괴검출솔분별위18.5％、41.8％、60.7％、86.3％.(3)교정영향경동맥반괴적다인소logistic회귀분석,현시고정식심솔조발생경동맥반괴적풍험비저정식심솔조증가22.6％(OR=1.226,95％CI:1.018 ～ 1.477).결론 고정식심솔능증가경동맥반괴적발생풍험.
Objective To explore the effect of high resting heart rate (RHR) on the detection rate of carotid artery plaque in elderly population.Methods From June 2010 to June 2011,a total of 5 852 participants randomly selected and recruited from 101 510 workers of a Tangshan Kailuan Company in this cohort study.All the information was obtained through unified questionnaires.Blood tests and RHR were measured and color-ultrasound performed to detect the carotid artery plaque.All the subjects were divided into groups according to RHR,with ≤ 80 bpm/min as low RHR group and ＞80 bpm/min as high RHR group.The detection rates of carotid artery plaque were compared between the two groups after stratification on both gender and age.Single and multiple factors logistic regression analyses were used to analyze the factors related to carotid artery plaques.Results 1) The detection rate of carotid artery plaque in high RHR group was higher than that of low RHR group (48.9％ vs.41.5％,P＜0.001).Between the high or low RHR groups,the detection rates of carotid artery plaque were 58.7％ and 52.1％ in males,26.9％ and 25.1％ in females.2) The detection rates of carotid artery plaque increased with age:19.5％,42.9％,67.6％ and 86.5％ in ＜ 50,50-,60-and ≥ 70year olds.They were 25.1％,50.0％,70.5％ and 87.5％ in the high RHR group and,18.5％,41.8％,60.7％ and 86.3％ in the low RHR group.3) After adjustment for influence factors related to carotid artery plaque,the risk on carotid artery in high RHR group had an increase of 22.6％,when compared with that of the low RHR group.The OR value was 1.226(95％CI:1.018-1.477).Conclusion High RHR could increase the risk of carotid artery plaque.
