CAJ | 학술논문

目的探讨静态生活方式和静坐时间对MS及T2DM的影响.方法采用多阶段分层整群抽样的方法,2010-2011年对福建省6 016名≥18岁常住居民进行人口学信息及身体活动状况等问卷调查,同时测量身高、体重、WC和血压并检测血糖、血脂,依据2005年国际糖尿病联盟(IDF)MS诊断标准和1999年WHO糖尿病诊断标准进行MS及T2DM病例诊断,并应用logistic回归分析静态生活方式与MS及T2DM的相关性.结果福建省≥18岁人群MS及T2DM患病率分别为19.0％及8.0％,完全静坐行为的比例为18.1％,每日平均静坐时间为4.3h,对照组(C)、单纯MS组(M)、单纯糖尿病组(T)、糖尿病合并MS组(MT)静坐行为比例不同,差异有统计学意义(P＜0.001).经年龄、性别、吸烟、饮酒、BMI、文化程度、职业和完全静坐/静坐时间校正后,与静坐时间＜2.0 h/d组相比,2.0～3.5 h/d组与MT组患病显著相关(OR=1.44,95％CI:1.03～ 2.03,P＜0.05),3.5 ～ 6.0 h/d组及≥6.0 h/d组与M、T及MT组患病均显著相关(OR值分别为1.49～ 1.76及1.28 ～ 1.58,95％CI分别为1.19 ～ 2.45及1.02 ～ 2.23,P＜0.05),完全静坐行为与MT组(OR=1.82,95％CI:1.33～ 2.48,P＜0.01)及M组(OR=1.43,95％CI:1.14～1.78,P＜0.01)患病风险存在独立的关联.结论静坐生活方式与MS及T2DM患病风险可能存在相关,但仍需进一步在纵向研究中加以证实.
목적 탐토정태생활방식화정좌시간대MS급T2DM적영향.방법 채용다계단분층정군추양적방법,2010-2011년대복건성6 016명≥18세상주거민진행인구학신식급신체활동상황등문권조사,동시측량신고、체중、WC화혈압병검측혈당、혈지,의거2005년국제당뇨병련맹(IDF)MS진단표준화1999년WHO당뇨병진단표준진행MS급T2DM병례진단,병응용logistic회귀분석정태생활방식여MS급T2DM적상관성.결과 복건성≥18세인군MS급T2DM환병솔분별위19.0％급8.0％,완전정좌행위적비례위18.1％,매일평균정좌시간위4.3h,대조조(C)、단순MS조(M)、단순당뇨병조(T)、당뇨병합병MS조(MT)정좌행위비례불동,차이유통계학의의(P＜0.001).경년령、성별、흡연、음주、BMI、문화정도、직업화완전정좌/정좌시간교정후,여정좌시간＜2.0 h/d조상비,2.0～3.5 h/d조여MT조환병현저상관(OR=1.44,95％CI:1.03～ 2.03,P＜0.05),3.5 ～ 6.0 h/d조급≥6.0 h/d조여M、T급MT조환병균현저상관(OR치분별위1.49～ 1.76급1.28 ～ 1.58,95％CI분별위1.19 ～ 2.45급1.02 ～ 2.23,P＜0.05),완전정좌행위여MT조(OR=1.82,95％CI:1.33～ 2.48,P＜0.01)급M조(OR=1.43,95％CI:1.14～1.78,P＜0.01)환병풍험존재독립적관련.결론 정좌생활방식여MS급T2DM환병풍험가능존재상관,단잉수진일보재종향연구중가이증실.
Objective To explore the association of sedentary life style with risk of metabolic syndrome (MS) and diabetes mellitus type 2 (T2DM).Methods A total of 6 016 local residents aged 18 years or older in Fujian province were recruited by multi-stage stratified cluster sampling method in 2010-2011.Data,including demographic information,physical activity and sedentary time were collected.Indices related to height,weight,waist circumference,blood pressure and blood lipid were determined while MS and T2DM were diagnosed by IDF (2005) and WHO (1999) criteria.Logistic regression was used to estimate the correlations between sedentary behavior and MS or T2DM.Results The prevalence rates of MS and T2DM were 19.0％ and 8.0％ respectively,in local residents aged 18 years or older,in Fujian province.The overall rate of sedentary behavior was 18.1％,with the mean sedentary time as 4.3 hours.Both data showed significantly differences (P＜0.001) among control group,MS without T2DM group,MS with T2DM group and T2DM without MS group.Compared with the group of sedentary time ＜2.0 h/d,1) the group with 2.0-3.5 h/d was significantly correlated with MT group (OR=1.44,95％ CI:1.03-2.03,P＜0.05),2) groups of 3.5-6.0 h/d and ≥6.0 h/d were significantly correlated with M,T,MT group,respectively (OR:1.49-1.76 and 1.28-1.58 respectively,95％ CI:1.19-2.45 and 1.02-2.23 respectively,P＜ 0.05),and 3) sedentary behavior was independently associated with an increased risk of MT group (OR=1.82,95％ CI:1.33-2.48,P＜0.01) and M group (OR=1.43,95％CI:1.14-1.78,P＜0.01),after the adjustment for factors as age,sex,cigarette smoking,alcohol drinking,BMI,education,occupation,sedentary behavior/sedentary time.Conclusion MS and T2DM were associated with sedentary lifestyle,but these findings should be confirmed through further longitudinal studies.