中华麻醉学杂志
中華痳醉學雜誌
중화마취학잡지
CHINESE JOURNAL OF ANESTHESIOLOGY
2013年
10期
1233-1235
,共3页
卢悦淳%孙健%高春霖%吕国义%王国林
盧悅淳%孫健%高春霖%呂國義%王國林
로열순%손건%고춘림%려국의%왕국림
利多卡因%神经传导阻滞%闭孔神经%剂量效应关系,药物
利多卡因%神經傳導阻滯%閉孔神經%劑量效應關繫,藥物
리다잡인%신경전도조체%폐공신경%제량효응관계,약물
Lidocaine%Nerve block%Obturator nerve%Dose-response relationship,drug
目的 确定1.5%利多卡因用于经尿道膀胱肿瘤电切术患者闭孔神经阻滞时的半数有效容量(EVs).方法 选择拟行经尿道膀胱肿瘤电切术的膀胱侧壁肿瘤患者36例,术前均确定需行闭孔神经阻滞,ASA分级Ⅰ或Ⅱ级,BMI 19~ 30 kg/m2,年龄18 ~64岁,在周围神经刺激仪引导下经传统耻骨入路用1.5%利多卡因行闭孔神经阻滞,1.5%利多卡因容量根据序贯法确定,初始容量10 ml,相邻容量比值1.1.闭孔神经阻滞成功为阳性反应.计算1.5%利多卡因用于闭孔神经阻滞时的EV.及其95%可信区间(CI).结果 1.5%利多卡因用于周围神经刺激仪引导下经耻骨入路闭孔神经阻滞时的EV50为5.53 ml,95%CI为5.10~6.00 ml.结论 1.5%利多卡因用于经尿道膀胱肿瘤电切术患者闭孔神经阻滞时的EV.为5.53 ml.
目的 確定1.5%利多卡因用于經尿道膀胱腫瘤電切術患者閉孔神經阻滯時的半數有效容量(EVs).方法 選擇擬行經尿道膀胱腫瘤電切術的膀胱側壁腫瘤患者36例,術前均確定需行閉孔神經阻滯,ASA分級Ⅰ或Ⅱ級,BMI 19~ 30 kg/m2,年齡18 ~64歲,在週圍神經刺激儀引導下經傳統恥骨入路用1.5%利多卡因行閉孔神經阻滯,1.5%利多卡因容量根據序貫法確定,初始容量10 ml,相鄰容量比值1.1.閉孔神經阻滯成功為暘性反應.計算1.5%利多卡因用于閉孔神經阻滯時的EV.及其95%可信區間(CI).結果 1.5%利多卡因用于週圍神經刺激儀引導下經恥骨入路閉孔神經阻滯時的EV50為5.53 ml,95%CI為5.10~6.00 ml.結論 1.5%利多卡因用于經尿道膀胱腫瘤電切術患者閉孔神經阻滯時的EV.為5.53 ml.
목적 학정1.5%리다잡인용우경뇨도방광종류전절술환자폐공신경조체시적반수유효용량(EVs).방법 선택의행경뇨도방광종류전절술적방광측벽종류환자36례,술전균학정수행폐공신경조체,ASA분급Ⅰ혹Ⅱ급,BMI 19~ 30 kg/m2,년령18 ~64세,재주위신경자격의인도하경전통치골입로용1.5%리다잡인행폐공신경조체,1.5%리다잡인용량근거서관법학정,초시용량10 ml,상린용량비치1.1.폐공신경조체성공위양성반응.계산1.5%리다잡인용우폐공신경조체시적EV.급기95%가신구간(CI).결과 1.5%리다잡인용우주위신경자격의인도하경치골입로폐공신경조체시적EV50위5.53 ml,95%CI위5.10~6.00 ml.결론 1.5%리다잡인용우경뇨도방광종류전절술환자폐공신경조체시적EV.위5.53 ml.
Objective To determine the effective volume of 1.5% lidocaine for obturator nerve block (ONB) in 50% of patients (EV50) undergoing transurethral resection of bladder tumor (TURBT).Methods Thirty-six ASA physical status Ⅰ or Ⅱ patients with bladder tumor,aged 18-64 yr,with body mass index of 19-30 kg/m2,scheduled for elective TURBT and required ONB before TURBT,were enrolled in the study.ONB was performed with 1.5 % lidocaine using the pubic approach under the guidance of a nerve stimulator.The volume of 1.5% lidocaine was determined by up-and-down sequential trial.The initial volume of hdocaine was 10 ml and the ratio between the two successive volumes was 1.1.Successful ONB was considered to be positive response.The EV50 and 95 % confidence interval (CI) of 1.5 % lidocaine for ONB were calculated.Results The EV50 of 1.5 % lidocaine for ONB was 5.53 rnl and the 95 % CI was 5.10-6.00 ml.Conclusion The EV50 of 1.5 % lidocaine is 5.53 ml when used for ONB in patients undergoing TURBT.