CAJ | 학술논문

目的评价七氟醚麻醉对低龄婴儿左心功能的影响.方法择期拟行体表血管瘤切除术患儿16例,性别不限,28 ～ 75日龄,体重4.0～6.1 kg,ASA分级Ⅰ级.吸入6％七氟醚4min时行气管插管,机械通气,麻醉维持:吸入七氟醚,呼气末浓度4.48％～ 5.12％.分别于麻醉诱导前(T0)、气管插管前即刻(T1)、气管插管后10 min(T2)、气管插管后30 min(T3)、拔除气管导管后20 min(T4)、拔除气管导管后1 h(T5)时采用组织多普勒频谱技术确定Tei指数,记录术中心血管事件发生情况.结果与T0时比较,T1-4时Tei指数增加(P＜0.05或0.01),T5时Tei指数差异无统计学意义(P＞0.05).术中血压和心率平稳,未发生心血管事件.结论虽然七氟醚麻醉未诱发低龄婴儿心血管事件,但是在一定程度上降低了左心功能.
목적 평개칠불미마취대저령영인좌심공능적영향.방법 택기의행체표혈관류절제술환인16례,성별불한,28 ～ 75일령,체중4.0～6.1 kg,ASA분급Ⅰ급.흡입6％칠불미4min시행기관삽관,궤계통기,마취유지:흡입칠불미,호기말농도4.48％～ 5.12％.분별우마취유도전(T0)、기관삽관전즉각(T1)、기관삽관후10 min(T2)、기관삽관후30 min(T3)、발제기관도관후20 min(T4)、발제기관도관후1 h(T5)시채용조직다보륵빈보기술학정Tei지수,기록술중심혈관사건발생정황.결과 여T0시비교,T1-4시Tei지수증가(P＜0.05혹0.01),T5시Tei지수차이무통계학의의(P＞0.05).술중혈압화심솔평은,미발생심혈관사건.결론 수연칠불미마취미유발저령영인심혈관사건,단시재일정정도상강저료좌심공능.
Objective To evaluate the effects of sevoflurane anesthesia on the left ventricular function in young infants.Methods Sixteen ASA physical status Ⅰ pediatric patients,aged 28-75 days,weighing 4.0-6.1 kg,undergoing elective resection of hemangioma on the body surface under general anesthesia with sevoflurane were studied.After the pediatric patients inhaled 6 ％ sevoflurane for 4 min,tracheal intubation was performed,and the pediatric patients were mechanically ventilated.Anesthesia was maintained with sevoflurane with the endtidal concentration of 4.48％-5.12％.Transthoracic echocardiographic examinations were performed before induction of anesthesia (baseline,T0),immediately before intubation (T1),at 10 and 30 min after intubation (T2,3),and at 20 min and 1 h after extubation (T4,5) to calculate Tei index.Results Compared with the baseline value at T0,Tei index was significantly increased at T1-4 (P ＜ 0.05 or 0.01),and no significant change was found in Tei index at T5 (P ＞ 0.05).The blood pressure and heart rate were stable and no adverse cardiovascular events were found during surgery.Conclusion Although sevoflurane anesthesia does not induce cardiovascular events,it decreases the left ventricular function to some extent in young infants.