中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2009年
6期
612-614
,共3页
吴文俊%李卫平%倪连松%汪大望%沈飞霞%陈以勒
吳文俊%李衛平%倪連鬆%汪大望%瀋飛霞%陳以勒
오문준%리위평%예련송%왕대망%침비하%진이륵
内脂素%糖尿病%2型%周围血管病变%炎症因子
內脂素%糖尿病%2型%週圍血管病變%炎癥因子
내지소%당뇨병%2형%주위혈관병변%염증인자
Visfatin%Diabetes mellitus%type 2%Peripheral arterial diseases%In flammatory fator
按彩色多普勒超声检查外周动脉结果分组,2型糖尿病合并外周动脉疾病组(T2DM-PAD组)47例、2型糖尿病无外周动脉疾病组(T2DM组)40例、正常对照组25名,结果显示,T2DM-PAD组、T2DM组血清内脂素水平高于正常对照组[(63.85±15.94和54.96±12.58 vs 46.29±6.70)ng/ml,均P<0.01],T2DM-PAD组显著高于T2DM组(P<0.05).Pearson相关分析表明,血清内脂素与超敏c反应蛋白、白细胞介素6、颈动脉内膜中层厚度、腰臀比、纤维蛋白原、空腹血糖均呈正相关(P<0.05或P<0.01).
按綵色多普勒超聲檢查外週動脈結果分組,2型糖尿病閤併外週動脈疾病組(T2DM-PAD組)47例、2型糖尿病無外週動脈疾病組(T2DM組)40例、正常對照組25名,結果顯示,T2DM-PAD組、T2DM組血清內脂素水平高于正常對照組[(63.85±15.94和54.96±12.58 vs 46.29±6.70)ng/ml,均P<0.01],T2DM-PAD組顯著高于T2DM組(P<0.05).Pearson相關分析錶明,血清內脂素與超敏c反應蛋白、白細胞介素6、頸動脈內膜中層厚度、腰臀比、纖維蛋白原、空腹血糖均呈正相關(P<0.05或P<0.01).
안채색다보륵초성검사외주동맥결과분조,2형당뇨병합병외주동맥질병조(T2DM-PAD조)47례、2형당뇨병무외주동맥질병조(T2DM조)40례、정상대조조25명,결과현시,T2DM-PAD조、T2DM조혈청내지소수평고우정상대조조[(63.85±15.94화54.96±12.58 vs 46.29±6.70)ng/ml,균P<0.01],T2DM-PAD조현저고우T2DM조(P<0.05).Pearson상관분석표명,혈청내지소여초민c반응단백、백세포개소6、경동맥내막중층후도、요둔비、섬유단백원、공복혈당균정정상관(P<0.05혹P<0.01).
According to the results of Doppler examination,47 eases of type 2 diabetic patients with peripheral arterial disease(T2DM-PAD),40 cases of type 2 diabetic patients without PAD(T2DM),and 25 subjects without type 2 diabetes mellitus and PAD(control)were involved in this study.The results showed that serum visfatin concentrations in T2DM-PAD and T2DM groups were higher than that in centrel group[(63.85±15.94 and 54.96±12.58 vs 46.29±6.70)ng/ml.both P<0.01].and serum visfatin concentration in T2DM-PAD group was higher than that in T2DM group(P<0.05).Pearson's correlation analysis demonstrated that serum visfatin level was positively correlated with high sensitive C reactive protein.interleukin-6.carotid intima-media thickness,waist to hip ratio,fibrinogen,and fasting plasma glucose(P<0.05 or P<0.01).