中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2009年
6期
628-630
,共3页
姜丽红%刘戈力%杨菁岩%马咸成
薑麗紅%劉戈力%楊菁巖%馬鹹成
강려홍%류과력%양정암%마함성
二甲双胍%假性黑棘皮病%高胰岛素血症%肥胖症%儿童
二甲雙胍%假性黑棘皮病%高胰島素血癥%肥胖癥%兒童
이갑쌍고%가성흑극피병%고이도소혈증%비반증%인동
Metformin%Aeanthosis nigricans%Hyperinsulinemia%Obesity:Children
对88例高胰岛素血症假性黑棘皮病(AN)肥胖儿童给予二甲双胍治疗3个月和6个月后,对空腹胰岛素、葡萄糖耐量试验2 h胰岛素和AN评分等进行评价,结果表明二甲双胍可改善假性AN肥胖患儿高胰岛素血症状态,AN分级方法可作为病情变化的无创监测手段.
對88例高胰島素血癥假性黑棘皮病(AN)肥胖兒童給予二甲雙胍治療3箇月和6箇月後,對空腹胰島素、葡萄糖耐量試驗2 h胰島素和AN評分等進行評價,結果錶明二甲雙胍可改善假性AN肥胖患兒高胰島素血癥狀態,AN分級方法可作為病情變化的無創鑑測手段.
대88례고이도소혈증가성흑극피병(AN)비반인동급여이갑쌍고치료3개월화6개월후,대공복이도소、포도당내량시험2 h이도소화AN평분등진행평개,결과표명이갑쌍고가개선가성AN비반환인고이도소혈증상태,AN분급방법가작위병정변화적무창감측수단.
Tatal 88 obese children with hyperinsulinemia and acanthosis nigricans (AN)were given metformin for 3 and 6 months.The levels of fast insulin,2 h postprandial insulin.and AN score were lower after treatment.Metformin therapy on obese children with hyperinsulinemia and AN was safe.AN score may be an appropriate non-invasive index monitoring disease prognosis.
