中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2011年
1期
28-31
,共4页
张永奎%刘晓光%竺王玉%周世权%王晔恺%胡晓斐%郑笑娟%赵臣银%袁惠萍
張永奎%劉曉光%竺王玉%週世權%王曄愷%鬍曉斐%鄭笑娟%趙臣銀%袁惠萍
장영규%류효광%축왕옥%주세권%왕엽개%호효비%정소연%조신은%원혜평
甲状腺%碘%流行病学
甲狀腺%碘%流行病學
갑상선%전%류행병학
Thyroid%Iodine%Epidemiology
目的 调查舟山海岛地区居民甲状腺疾病和碘营养状况,分析二者的相互关系.方法 通过整群随机抽样的方法选取了3284名舟山成年居民进行了尿碘检测,并进行流行病学问卷调查、甲状腺B超检查、甲状腺功能测定.结果 舟山海岛地区成年居民尿碘中位数为226.0μg/L,其中城镇居民320.7 μg/L、盐民122.2 μg/L、农民188.9 μg/L、渔民193.6 μg/L、僧侣271.7 μg/L.舟山地区3284名居民弥漫性甲状腺肿、结节性甲状腺肿、胶质性甲状腺肿、甲状腺腺瘤、甲状腺癌、甲状腺功能亢进(甲亢)、亚临床甲亢、甲状腺功能减退(甲减)、亚临床甲减的患病率分别为1.7%、25.3%、8.7%、0.2%、0.4%、0.5%、0.8%、0.03%和1.0%,甲状腺过氧化物酶抗体(TPOAb)阳性率为9.5%.甲状腺疾病患病率女性明显高于男性(P＜0.05),且随年龄的增长而增高(P＜0.05).经logistic回归模型分析甲状腺疾病患病率与年收入、食用海产品、吸烟史、饮酒史、饮茶史、尿碘值等均无明显相关性(P＞0.05).结论 舟山地区居民碘摄入充足,是否实施全民食盐加碘值得商榷;舟山海岛地区甲状腺疾病的患病率较高可能与碘过量有关.
目的 調查舟山海島地區居民甲狀腺疾病和碘營養狀況,分析二者的相互關繫.方法 通過整群隨機抽樣的方法選取瞭3284名舟山成年居民進行瞭尿碘檢測,併進行流行病學問捲調查、甲狀腺B超檢查、甲狀腺功能測定.結果 舟山海島地區成年居民尿碘中位數為226.0μg/L,其中城鎮居民320.7 μg/L、鹽民122.2 μg/L、農民188.9 μg/L、漁民193.6 μg/L、僧侶271.7 μg/L.舟山地區3284名居民瀰漫性甲狀腺腫、結節性甲狀腺腫、膠質性甲狀腺腫、甲狀腺腺瘤、甲狀腺癌、甲狀腺功能亢進(甲亢)、亞臨床甲亢、甲狀腺功能減退(甲減)、亞臨床甲減的患病率分彆為1.7%、25.3%、8.7%、0.2%、0.4%、0.5%、0.8%、0.03%和1.0%,甲狀腺過氧化物酶抗體(TPOAb)暘性率為9.5%.甲狀腺疾病患病率女性明顯高于男性(P＜0.05),且隨年齡的增長而增高(P＜0.05).經logistic迴歸模型分析甲狀腺疾病患病率與年收入、食用海產品、吸煙史、飲酒史、飲茶史、尿碘值等均無明顯相關性(P＞0.05).結論 舟山地區居民碘攝入充足,是否實施全民食鹽加碘值得商榷;舟山海島地區甲狀腺疾病的患病率較高可能與碘過量有關.
목적 조사주산해도지구거민갑상선질병화전영양상황,분석이자적상호관계.방법 통과정군수궤추양적방법선취료3284명주산성년거민진행료뇨전검측,병진행류행병학문권조사、갑상선B초검사、갑상선공능측정.결과 주산해도지구성년거민뇨전중위수위226.0μg/L,기중성진거민320.7 μg/L、염민122.2 μg/L、농민188.9 μg/L、어민193.6 μg/L、승려271.7 μg/L.주산지구3284명거민미만성갑상선종、결절성갑상선종、효질성갑상선종、갑상선선류、갑상선암、갑상선공능항진(갑항)、아림상갑항、갑상선공능감퇴(갑감)、아림상갑감적환병솔분별위1.7%、25.3%、8.7%、0.2%、0.4%、0.5%、0.8%、0.03%화1.0%,갑상선과양화물매항체(TPOAb)양성솔위9.5%.갑상선질병환병솔녀성명현고우남성(P＜0.05),차수년령적증장이증고(P＜0.05).경logistic회귀모형분석갑상선질병환병솔여년수입、식용해산품、흡연사、음주사、음다사、뇨전치등균무명현상관성(P＞0.05).결론 주산지구거민전섭입충족,시부실시전민식염가전치득상각;주산해도지구갑상선질병적환병솔교고가능여전과량유관.
Objective To investigate iodine nutrition and thyroid health status among residents in Zhoushan archipelago, and to analyse their relationship.Methods A total of 3 284 residents in Zhoushan archipelago were surveyed by questionnaire and their thyroids were examined by B-mode ultrasound.The levels of urinary iodine and thyroid function were detected.Results The median level of urinary iodine in 3 284 residents was 226.0 μg/L, being 320.7 μg/L in citizens, 188.9 μg/L in farmers, 122.2 μg/L in salt-makers, 193.6 μg/L in fishers, and 271.7 μg/L in buddhist.The prevalence of diffuse goiter, nodular goiter, colloid goiter, thyroid adenoma, thyroid carcinoma, hyperthyroidism, subclinical hyperthyroidism, hypothyroidism, subclinical hypothyroidism, and positve rate of TPOAb were 1.7% ,25.3% ,8.7% ,0.2% ,0.4% ,0.5% ,0.8% ,0.03%,1.0% ,and 9.5% repectively.The prevalence of thyroid diseases was increasing with aging, and higher in women than in men (P＜0.05).There was no significant relationship of the thyroid diseases with seafood, smoking,drinking, and tea (P＞0.05).Conclusions The citizens of Zhoushan archipelago have adequate iodine intake.It is pertinent to discuss Universal Salt Iodization.Excessive iodine intake may contribute to the high prevalence rate of thyroid diseases in Zhoushan.
