CAJ | 학술논문

碳酸锂作为精神性疾病的治疗药物在使用中发现可导致甲状腺功能减退、白细胞增多,因此被移作在一些特殊情况下甲状腺功能亢进症的治疗.当甲状腺功能亢进症患者对硫脲类抗甲状腺药物过敏、无效或合并白细胞减少时,碳酸锂可能是一种值得探索的治疗选择.但在使用中应注意监测血药浓度,选择较小剂量,避免药物的不良反应.
탄산리작위정신성질병적치료약물재사용중발현가도치갑상선공능감퇴、백세포증다,인차피이작재일사특수정황하갑상선공능항진증적치료.당갑상선공능항진증환자대류뇨류항갑상선약물과민、무효혹합병백세포감소시,탄산리가능시일충치득탐색적치료선택.단재사용중응주의감측혈약농도,선택교소제량,피면약물적불량반응.
[Summary] Lithium carbonate has been used as a psychiatric drug with some adverse effects such as hypothyroidism and leukocytosis.The adverse effects have been exploited for the treatment of hyperthyroid patients in particular conditions.It might be an alternative therapy for controlling hyperthyroidism in patients who can not tolerate or do not respond to thionamides or suffer from leukopenic condition.But it is important that monitoring serum lithium level,using smaller dose,and avoiding serious side-effects during the therapy of lithium carbonate should be carried out.