CAJ | 학술논문

目的了解新疆喀什地区碘营养状况,并探讨尿碘水平与甲状腺大小的关系.方法在喀什地区12县市采取抽样调查,砷铈催化分光光度测定尿碘,砷铈氧化还原法测定水碘,直接滴定法检测盐碘,并抽取3个县儿童用B超检查甲状腺各径及容积.结果喀什地区水碘中位数＜10μg/L,属于碘缺乏病病区,随着碘盐覆盖率(98.7％)和碘盐合格率(96.8％)的提高,喀什地区尿碘中位数为177.05 μg/L,总体属碘适量;但不同县之间尿碘频数分布差异较大,有6个县碘缺乏比例＞20％,有5个县碘过量比例＞20％;维吾尔族和汉族、高原和平原、城市与农村儿童碘营养状况均无明显差异;英吉沙、伽师和莎车无甲状腺肿儿童的甲状腺右宽和右厚与尿碘呈正相关(r=0.113,P=0.012;r=0.092,P=0.04).结论新疆喀什地区碘缺乏状态已基本纠正,但不同县市之间需更为细化的补碘方案以防止碘缺乏或碘过量所致的甲状腺疾病.
목적 료해신강객십지구전영양상황,병탐토뇨전수평여갑상선대소적관계.방법 재객십지구12현시채취추양조사,신시최화분광광도측정뇨전,신시양화환원법측정수전,직접적정법검측염전,병추취3개현인동용B초검사갑상선각경급용적.결과 객십지구수전중위수＜10μg/L,속우전결핍병병구,수착전염복개솔(98.7％)화전염합격솔(96.8％)적제고,객십지구뇨전중위수위177.05 μg/L,총체속전괄량;단불동현지간뇨전빈수분포차이교대,유6개현전결핍비례＞20％,유5개현전과량비례＞20％;유오이족화한족、고원화평원、성시여농촌인동전영양상황균무명현차이;영길사、가사화사차무갑상선종인동적갑상선우관화우후여뇨전정정상관(r=0.113,P=0.012;r=0.092,P=0.04).결론 신강객십지구전결핍상태이기본규정,단불동현시지간수경위세화적보전방안이방지전결핍혹전과량소치적갑상선질병.
Objective To investigate the nutritional status of iodine in children in Kashi and to evaluate the relationship between urinary iodine and thyroid size.Methods Twelve counties in Kashi were investigated.Urinary iodine was determined by arsenic-cerium catalytic spectrophotometry,and iodine in water by arsenic-cerium oxidationreduction method,and iodized salt was tested by direct titration.Type B ultrasonography to determine length and thickness of thyroid gland was performed in selective counties.Result The median water iodine was ＜ 10 μg/L,but with the rise of coverage rate and qualified rate of iodized salt,the median urinary iodine became 177.05 μg/L.The frequency distribution was different among different counties,there were 6 counties (＞20％) being iodine deficient,and 5 counties (＞20％) with iodine excess.Moreover,urinau iodine showed no difference between Uygur and Han,upland and plain,city and countryside.Furthermore,urinary iodine was correlated with right lobe width and thickness (r=0.113,P=0.012; r=0.092,P=0.04).Conclusion The iodine deficient situation is basically corrected in Kashi,however a more refined iodine supplement project is needed to prevent thyroid diseases.